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Items: 1 to 20 of 27


Biochemical and molecular characterization of the hyaluronidase from Bothrops atrox Peruvian snake venom.

Vivas-Ruiz DE, Gonzalez-Kozlova EE, Delgadillo J, Palermo PM, Sandoval GA, Lazo F, Rodríguez E, Chávez-Olórtegui C, Yarlequé A, Sanchez EF.

Biochimie. 2019 Jul;162:33-45. doi: 10.1016/j.biochi.2019.03.022. Epub 2019 Apr 1.


Direct Fibrinolytic Snake Venom Metalloproteinases Affecting Hemostasis: Structural, Biochemical Features and Therapeutic Potential.

Sanchez EF, Flores-Ortiz RJ, Alvarenga VG, Eble JA.

Toxins (Basel). 2017 Dec 5;9(12). pii: E392. doi: 10.3390/toxins9120392. Review.


Biochemical, biological and molecular characterization of an L-Amino acid oxidase (LAAO) purified from Bothrops pictus Peruvian snake venom.

Lazo F, Vivas-Ruiz DE, Sandoval GA, Rodríguez EF, Kozlova EEG, Costal-Oliveira F, Chávez-Olórtegui C, Severino R, Yarlequé A, Sanchez EF.

Toxicon. 2017 Dec 1;139:74-86. doi: 10.1016/j.toxicon.2017.10.001. Epub 2017 Oct 9.


Neutralization of toxicological activities of medically-relevant Bothrops snake venoms and relevant toxins by two polyvalent bothropic antivenoms produced in Peru and Brazil.

Estevao-Costa MI, Gontijo SS, Correia BL, Yarleque A, Vivas-Ruiz D, Rodrigues E, Chávez-Olortegui C, Oliveira LS, Sanchez EF.

Toxicon. 2016 Nov;122:67-77. doi: 10.1016/j.toxicon.2016.09.010. Epub 2016 Sep 15.


Molecular characterization of Lys49 and Asp49 phospholipases A₂from snake venom and their antiviral activities against Dengue virus.

Cecilio AB, Caldas S, Oliveira RA, Santos AS, Richardson M, Naumann GB, Schneider FS, Alvarenga VG, Estevão-Costa MI, Fuly AL, Eble JA, Sanchez EF.

Toxins (Basel). 2013 Oct 15;5(10):1780-98. doi: 10.3390/toxins5101780.


Antivenom effects of 1,2,3-triazoles against Bothrops jararaca and Lachesis muta snakes.

Domingos TF, Moura Lde A, Carvalho C, Campos VR, Jordão AK, Cunha AC, Ferreira VF, de Souza MC, Sanchez EF, Fuly AL.

Biomed Res Int. 2013;2013:294289. doi: 10.1155/2013/294289. Epub 2013 Apr 22.


Coagulant thrombin-like enzyme (barnettobin) from Bothrops barnetti venom: molecular sequence analysis of its cDNA and biochemical properties.

Vivas-Ruiz DE, Sandoval GA, Mendoza J, Inga RR, Gontijo S, Richardson M, Eble JA, Yarleque A, Sanchez EF.

Biochimie. 2013 Jul;95(7):1476-86. doi: 10.1016/j.biochi.2013.03.015. Epub 2013 Apr 9.


The thrombolytic action of a proteolytic fraction (P1G10) from Carica candamarcensis.

Bilheiro RP, Braga AD, Filho ML, Carvalho-Tavares J, Agero U, Carvalho Md, Sanchez EF, Salas CE, Lopes MT.

Thromb Res. 2013 Apr;131(4):e175-82. doi: 10.1016/j.thromres.2013.01.028. Epub 2013 Mar 6.


Exploring the proteomes of the venoms of the Peruvian pit vipers Bothrops atrox, B. barnetti and B. pictus.

Kohlhoff M, Borges MH, Yarleque A, Cabezas C, Richardson M, Sanchez EF.

J Proteomics. 2012 Apr 3;75(7):2181-95. doi: 10.1016/j.jprot.2012.01.020. Epub 2012 Jan 24.


Role of collagens and perlecan in microvascular stability: exploring the mechanism of capillary vessel damage by snake venom metalloproteinases.

Escalante T, Ortiz N, Rucavado A, Sanchez EF, Richardson M, Fox JW, Gutiérrez JM.

PLoS One. 2011;6(12):e28017. doi: 10.1371/journal.pone.0028017. Epub 2011 Dec 8.


Cytotoxicity and inhibition of platelet aggregation caused by an l-amino acid oxidase from Bothrops leucurus venom.

Naumann GB, Silva LF, Silva L, Faria G, Richardson M, Evangelista K, Kohlhoff M, Gontijo CM, Navdaev A, de Rezende FF, Eble JA, Sanchez EF.

Biochim Biophys Acta. 2011 Jul;1810(7):683-94. doi: 10.1016/j.bbagen.2011.04.003. Epub 2011 Apr 22.


High resolution analysis of snake venom metalloproteinase (SVMP) peptide bond cleavage specificity using proteome based peptide libraries and mass spectrometry.

Paes Leme AF, Escalante T, Pereira JG, Oliveira AK, Sanchez EF, Gutiérrez JM, Serrano SM, Fox JW.

J Proteomics. 2011 Apr 1;74(4):401-10. doi: 10.1016/j.jprot.2010.12.002. Epub 2010 Dec 13.


The novel metalloproteinase atroxlysin-I from Peruvian Bothrops atrox (Jergón) snake venom acts both on blood vessel ECM and platelets.

Sanchez EF, Schneider FS, Yarleque A, Borges MH, Richardson M, Figueiredo SG, Evangelista KS, Eble JA.

Arch Biochem Biophys. 2010 Apr 1;496(1):9-20. doi: 10.1016/ Epub 2010 Jan 25.


Plumieribetin, a fish lectin homologous to mannose-binding B-type lectins, inhibits the collagen-binding alpha1beta1 integrin.

de Santana Evangelista K, Andrich F, Figueiredo de Rezende F, Niland S, Cordeiro MN, Horlacher T, Castelli R, Schmidt-Hederich A, Seeberger PH, Sanchez EF, Richardson M, Gomes de Figueiredo S, Eble JA.

J Biol Chem. 2009 Dec 11;284(50):34747-59. doi: 10.1074/jbc.M109.002873. Epub 2009 Oct 22.


Synthesis, biological, and theoretical evaluations of new 1,2,3-triazoles against the hemolytic profile of the Lachesis muta snake venom.

Campos VR, Abreu PA, Castro HC, Rodrigues CR, Jordão AK, Ferreira VF, de Souza MC, Santos Fda C, Moura LA, Domingos TS, Carvalho C, Sanchez EF, Fuly AL, Cunha AC.

Bioorg Med Chem. 2009 Nov 1;17(21):7429-34. doi: 10.1016/j.bmc.2009.09.031. Epub 2009 Sep 24.


Structural and functional characterization of a P-III metalloproteinase, leucurolysin-B, from Bothrops leucurus venom.

Sanchez EF, Gabriel LM, Gontijo S, Gremski LH, Veiga SS, Evangelista KS, Eble JA, Richardson M.

Arch Biochem Biophys. 2007 Dec 15;468(2):193-204. Epub 2007 Oct 12.


Effect of mutalysin II on vascular recanalization after thrombosis induction in the ear of the hairless mice model.

Agero U, Arantes RM, Lacerda-Queiroz N, Mesquita ON, Magalhães A, Sanchez EF, Carvalho-Tavares J.

Toxicon. 2007 Oct;50(5):698-706. Epub 2007 Jun 23.


Biochemical characterization and molecular cloning of a plasminogen activator proteinase (LV-PA) from bushmaster snake venom.

Sanchez EF, Felicori LF, Chavez-Olortegui C, Magalhaes HB, Hermogenes AL, Diniz MV, Junqueira-de-Azevedo IL, Magalhaes A, Richardson M.

Biochim Biophys Acta. 2006 Dec;1760(12):1762-71. Epub 2006 Sep 6.


Purification and properties of a coagulant thrombin-like enzyme from the venom of Bothrops leucurus.

Magalhães A, Magalhães HP, Richardson M, Gontijo S, Ferreira RN, Almeida AP, Sanchez EF.

Comp Biochem Physiol A Mol Integr Physiol. 2007 Apr;146(4):565-75. Epub 2006 Feb 14.


Interaction of a plasminogen activator proteinase, LV-PA with human alpha2-macroglobulin.

Hermogenes AL, Richardson M, Magalhaes A, Yarleque A, Rodriguez E, Sanchez EF.

Toxicon. 2006 Mar 15;47(4):490-4. Epub 2006 Feb 3.


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