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Items: 1 to 20 of 103

1.

Mechanisms of Incorporation for D-Amino Acid Probes That Target Peptidoglycan Biosynthesis.

Kuru E, Radkov A, Meng X, Egan A, Alvarez L, Dowson A, Booher G, Breukink E, Roper DI, Cava F, Vollmer W, Brun Y, VanNieuwenhze MS.

ACS Chem Biol. 2019 Dec 5. doi: 10.1021/acschembio.9b00664. [Epub ahead of print]

PMID:
31743648
2.

Plasticity of Escherichia coli cell wall metabolism promotes fitness and antibiotic resistance across environmental conditions.

Mueller EA, Egan AJ, Breukink E, Vollmer W, Levin PA.

Elife. 2019 Apr 9;8. pii: e40754. doi: 10.7554/eLife.40754.

3.

Towards the Native Binding Modes of Antibiotics that Target Lipid II.

Medeiros-Silva J, Jekhmane S, Breukink E, Weingarth M.

Chembiochem. 2019 Jul 15;20(14):1731-1738. doi: 10.1002/cbic.201800796. Epub 2019 May 22. Review.

4.

Peptidoglycan Remodeling Enables Escherichia coli To Survive Severe Outer Membrane Assembly Defect.

Morè N, Martorana AM, Biboy J, Otten C, Winkle M, Serrano CKG, Montón Silva A, Atkinson L, Yau H, Breukink E, den Blaauwen T, Vollmer W, Polissi A.

MBio. 2019 Feb 5;10(1). pii: e02729-18. doi: 10.1128/mBio.02729-18.

5.

Publisher Correction: Z-ring membrane anchors associate with cell wall synthases to initiate bacterial cell division.

Pazos M, Peters K, Casanova M, Palacios P, VanNieuwenhze M, Breukink E, Vicente M, Vollmer W.

Nat Commun. 2019 Jan 30;10(1):591. doi: 10.1038/s41467-019-08410-y.

6.

Regulation of the Peptidoglycan Polymerase Activity of PBP1b by Antagonist Actions of the Core Divisome Proteins FtsBLQ and FtsN.

Boes A, Olatunji S, Breukink E, Terrak M.

MBio. 2019 Jan 8;10(1). pii: e01912-18. doi: 10.1128/mBio.01912-18.

7.

Correction: Bacillus subtilis MraY in detergent-free system of nanodiscs wrapped by styrene-maleic acid copolymers.

Liu Y, Moura ECCM, Dörr JM, Scheidelaar S, Heger M, Egmond MR, Killian JA, Mohammadi T, Breukink E.

PLoS One. 2018 Dec 27;13(12):e0210135. doi: 10.1371/journal.pone.0210135. eCollection 2018.

8.

Z-ring membrane anchors associate with cell wall synthases to initiate bacterial cell division.

Pazos M, Peters K, Casanova M, Palacios P, VanNieuwenhze M, Breukink E, Vicente M, Vollmer W.

Nat Commun. 2018 Nov 30;9(1):5090. doi: 10.1038/s41467-018-07559-2. Erratum in: Nat Commun. 2019 Jan 30;10(1):591.

9.

Bacillus subtilis MraY in detergent-free system of nanodiscs wrapped by styrene-maleic acid copolymers.

Liu Y, Moura ECCM, Dörr JM, Scheidelaar S, Heger M, Egmond MR, Killian JA, Mohammadi T, Breukink E.

PLoS One. 2018 Nov 5;13(11):e0206692. doi: 10.1371/journal.pone.0206692. eCollection 2018. Erratum in: PLoS One. 2018 Dec 27;13(12):e0210135.

10.

High-resolution NMR studies of antibiotics in cellular membranes.

Medeiros-Silva J, Jekhmane S, Paioni AL, Gawarecka K, Baldus M, Swiezewska E, Breukink E, Weingarth M.

Nat Commun. 2018 Sep 27;9(1):3963. doi: 10.1038/s41467-018-06314-x.

11.

The Fluorescent D-Amino Acid NADA as a Tool to Study the Conditional Activity of Transpeptidases in Escherichia coli.

Montón Silva A, Otten C, Biboy J, Breukink E, VanNieuwenhze M, Vollmer W, den Blaauwen T.

Front Microbiol. 2018 Sep 4;9:2101. doi: 10.3389/fmicb.2018.02101. eCollection 2018.

12.

Structure of the essential peptidoglycan amidotransferase MurT/GatD complex from Streptococcus pneumoniae.

Morlot C, Straume D, Peters K, Hegnar OA, Simon N, Villard AM, Contreras-Martel C, Leisico F, Breukink E, Gravier-Pelletier C, Le Corre L, Vollmer W, Pietrancosta N, Håvarstein LS, Zapun A.

Nat Commun. 2018 Aug 9;9(1):3180. doi: 10.1038/s41467-018-05602-w.

13.

Coupling of polymerase and carrier lipid phosphatase prevents product inhibition in peptidoglycan synthesis.

Hernández-Rocamora VM, Otten CF, Radkov A, Simorre JP, Breukink E, VanNieuwenhze M, Vollmer W.

Cell Surf. 2018 Jun;2:1-13. doi: 10.1016/j.tcsw.2018.04.002.

14.

Induced conformational changes activate the peptidoglycan synthase PBP1B.

Egan AJF, Maya-Martinez R, Ayala I, Bougault CM, Banzhaf M, Breukink E, Vollmer W, Simorre JP.

Mol Microbiol. 2018 Nov;110(3):335-356. doi: 10.1111/mmi.14082. Epub 2018 Oct 25.

15.

Plantaricin NC8 from Lactobacillus plantarum causes cell membrane disruption to Micrococcus luteus without targeting lipid II.

Jiang H, Tang X, Zhou Q, Zou J, Li P, Breukink E, Gu Q.

Appl Microbiol Biotechnol. 2018 Sep;102(17):7465-7473. doi: 10.1007/s00253-018-9182-3. Epub 2018 Jul 7.

PMID:
29982926
16.

Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II binding.

Parmar A, Iyer A, Prior SH, Lloyd DG, Leng Goh ET, Vincent CS, Palmai-Pallag T, Bachrati CZ, Breukink E, Madder A, Lakshminarayanan R, Taylor EJ, Singh I.

Chem Sci. 2017 Dec 1;8(12):8183-8192. doi: 10.1039/c7sc03241b. Epub 2017 Oct 5.

17.

De novo identification of lipid II binding lipopeptides with antibacterial activity against vancomycin-resistant bacteria.

't Hart P, Wood TM, Tehrani KHME, van Harten RM, Śleszyńska M, Rentero Rebollo I, Hendrickx APA, Willems RJL, Breukink E, Martin NI.

Chem Sci. 2017 Dec 1;8(12):7991-7997. doi: 10.1039/c7sc03413j. Epub 2017 Oct 2.

18.

Interplay between Penicillin-binding proteins and SEDS proteins promotes bacterial cell wall synthesis.

Leclercq S, Derouaux A, Olatunji S, Fraipont C, Egan AJ, Vollmer W, Breukink E, Terrak M.

Sci Rep. 2017 Feb 24;7:43306. doi: 10.1038/srep43306.

19.

Defining the molecular structure of teixobactin analogues and understanding their role in antibacterial activities.

Parmar A, Prior SH, Iyer A, Vincent CS, Van Lysebetten D, Breukink E, Madder A, Taylor EJ, Singh I.

Chem Commun (Camb). 2017 Feb 7;53(12):2016-2019. doi: 10.1039/c6cc09490b.

PMID:
28124045
20.

Substitutions in PBP2b from β-Lactam-resistant Streptococcus pneumoniae Have Different Effects on Enzymatic Activity and Drug Reactivity.

Calvez P, Breukink E, Roper DI, Dib M, Contreras-Martel C, Zapun A.

J Biol Chem. 2017 Feb 17;292(7):2854-2865. doi: 10.1074/jbc.M116.764696. Epub 2017 Jan 6.

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