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Items: 1 to 20 of 40

1.

Speculations on the evolution of humoral adaptive immunity.

Horton MB, Hawkins ED, Heinzel S, Hodgkin PD.

Immunol Cell Biol. 2020 Mar 5. doi: 10.1111/imcb.12323. [Epub ahead of print]

PMID:
32133683
2.

Development and survival of MYC-driven lymphomas require the MYC antagonist MNT to curb MYC-induced apoptosis.

Nguyen HV, Vandenberg CJ, Ng AP, Robati MR, Anstee NS, Rimes J, Hawkins ED, Cory S.

Blood. 2020 Mar 26;135(13):1019-1031. doi: 10.1182/blood.2019003014.

3.

The Immuno-Modulatory Effects of Inhibitor of Apoptosis Protein Antagonists in Cancer Immunotherapy.

Michie J, Kearney CJ, Hawkins ED, Silke J, Oliaro J.

Cells. 2020 Jan 14;9(1). pii: E207. doi: 10.3390/cells9010207. Review.

4.

Plasmacytoid dendritic cells from parent strains of the NZB/W F1 lupus mouse contribute different characteristics to autoimmune propensity.

Zhan Y, Kong I, Chopin M, Macri C, Zhang JG, Xie J, Nutt SL, O'Keeffe M, Hawkins ED, Morand EF, Lew AM.

Immunol Cell Biol. 2020 Mar;98(3):203-214. doi: 10.1111/imcb.12313. Epub 2020 Feb 5.

PMID:
31916630
5.

Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease.

Lalaoui N, Boyden SE, Oda H, Wood GM, Stone DL, Chau D, Liu L, Stoffels M, Kratina T, Lawlor KE, Zaal KJM, Hoffmann PM, Etemadi N, Shield-Artin K, Biben C, Tsai WL, Blake MD, Kuehn HS, Yang D, Anderton H, Silke N, Wachsmuth L, Zheng L, Moura NS, Beck DB, Gutierrez-Cruz G, Ombrello AK, Pinto-Patarroyo GP, Kueh AJ, Herold MJ, Hall C, Wang H, Chae JJ, Dmitrieva NI, McKenzie M, Light A, Barham BK, Jones A, Romeo TM, Zhou Q, Aksentijevich I, Mullikin JC, Gross AJ, Shum AK, Hawkins ED, Masters SL, Lenardo MJ, Boehm M, Rosenzweig SD, Pasparakis M, Voss AK, Gadina M, Kastner DL, Silke J.

Nature. 2020 Jan;577(7788):103-108. doi: 10.1038/s41586-019-1828-5. Epub 2019 Dec 11.

PMID:
31827281
6.

PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia.

McRae HM, Garnham AL, Hu Y, Witkowski MT, Corbett MA, Dixon MP, May RE, Sheikh BN, Chiang W, Kueh AJ, Nguyen TA, Man K, Gloury R, Aubrey BJ, Policheni A, Di Rago L, Alexander WS, Gray DHD, Strasser A, Hawkins ED, Wilcox S, Gécz J, Kallies A, McCormack MP, Smyth GK, Voss AK, Thomas T.

Blood. 2019 Apr 18;133(16):1729-1741. doi: 10.1182/blood-2018-07-860726. Epub 2019 Feb 12.

7.

The haematopoietic stem cell niche: a new player in cardiovascular disease?

Al-Sharea A, Lee MKS, Purton LE, Hawkins ED, Murphy AJ.

Cardiovasc Res. 2019 Feb 1;115(2):277-291. doi: 10.1093/cvr/cvy308. Review.

PMID:
30590405
8.

Regulatory T Cells Suppress Effector T Cell Proliferation by Limiting Division Destiny.

Dowling MR, Kan A, Heinzel S, Marchingo JM, Hodgkin PD, Hawkins ED.

Front Immunol. 2018 Oct 30;9:2461. doi: 10.3389/fimmu.2018.02461. eCollection 2018.

9.

Defining the in vivo characteristics of acute myeloid leukemia cells behavior by intravital imaging.

Duarte D, Amarteifio S, Ang H, Kong IY, Ruivo N, Pruessner G, Hawkins ED, Lo Celso C.

Immunol Cell Biol. 2019 Feb;97(2):229-235. doi: 10.1111/imcb.12216. Epub 2018 Dec 13.

10.

Genetic regulation of antibody responsiveness to immunization in substrains of BALB/c mice.

Poyntz HC, Jones A, Jauregui R, Young W, Gestin A, Mooney A, Lamiable O, Altermann E, Schmidt A, Gasser O, Weyrich L, Jolly CJ, Linterman MA, Gros GL, Hawkins ED, Forbes-Blom E.

Immunol Cell Biol. 2019 Jan;97(1):39-53. doi: 10.1111/imcb.12199. Epub 2018 Oct 14.

11.

Constitutive overexpression of TNF in BPSM1 mice causes iBALT and bone marrow nodular lymphocytic hyperplasia.

Seillet C, Carr E, Lacey D, Stutz MD, Pellegrini M, Whitehead L, Rimes J, Hawkins ED, Roediger B, Belz GT, Bouillet P.

Immunol Cell Biol. 2019 Jan;97(1):29-38. doi: 10.1111/imcb.12197. Epub 2018 Sep 8.

12.

Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.

Baell JB, Leaver DJ, Hermans SJ, Kelly GL, Brennan MS, Downer NL, Nguyen N, Wichmann J, McRae HM, Yang Y, Cleary B, Lagiakos HR, Mieruszynski S, Pacini G, Vanyai HK, Bergamasco MI, May RE, Davey BK, Morgan KJ, Sealey AJ, Wang B, Zamudio N, Wilcox S, Garnham AL, Sheikh BN, Aubrey BJ, Doggett K, Chung MC, de Silva M, Bentley J, Pilling P, Hattarki M, Dolezal O, Dennis ML, Falk H, Ren B, Charman SA, White KL, Rautela J, Newbold A, Hawkins ED, Johnstone RW, Huntington ND, Peat TS, Heath JK, Strasser A, Parker MW, Smyth GK, Street IP, Monahan BJ, Voss AK, Thomas T.

Nature. 2018 Aug;560(7717):253-257. doi: 10.1038/s41586-018-0387-5. Epub 2018 Aug 1.

PMID:
30069049
13.

The interplay of leukemia cells and the bone marrow microenvironment.

Duarte D, Hawkins ED, Lo Celso C.

Blood. 2018 Apr 5;131(14):1507-1511. doi: 10.1182/blood-2017-12-784132. Epub 2018 Feb 27. Review.

14.

Excitatory Pathways from the Lateral Habenula Enable Propofol-Induced Sedation.

Gelegen C, Miracca G, Ran MZ, Harding EC, Ye Z, Yu X, Tossell K, Houston CM, Yustos R, Hawkins ED, Vyssotski AL, Dong HL, Wisden W, Franks NP.

Curr Biol. 2018 Feb 19;28(4):580-587.e5. doi: 10.1016/j.cub.2017.12.050. Epub 2018 Feb 1.

15.

Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML.

Duarte D, Hawkins ED, Akinduro O, Ang H, De Filippo K, Kong IY, Haltalli M, Ruivo N, Straszkowski L, Vervoort SJ, McLean C, Weber TS, Khorshed R, Pirillo C, Wei A, Ramasamy SK, Kusumbe AP, Duffy K, Adams RH, Purton LE, Carlin LM, Lo Celso C.

Cell Stem Cell. 2018 Jan 4;22(1):64-77.e6. doi: 10.1016/j.stem.2017.11.006. Epub 2017 Dec 21.

16.

The passive biomechanics of human pelvic collecting lymphatic vessels.

Athanasiou D, Edgar LT, Jafarnejad M, Nixon K, Duarte D, Hawkins ED, Jamalian S, Cunnea P, Lo Celso C, Kobayashi S, Fotopoulou C, Moore JE Jr.

PLoS One. 2017 Aug 21;12(8):e0183222. doi: 10.1371/journal.pone.0183222. eCollection 2017.

17.

Advanced microscopy and imaging techniques in immunology and cell biology.

Hawkins ED.

Immunol Cell Biol. 2017 Jul;95(6):499-500. doi: 10.1038/icb.2017.34. No abstract available.

PMID:
28674412
18.

Click chemistry enables preclinical evaluation of targeted epigenetic therapies.

Tyler DS, Vappiani J, Cañeque T, Lam EYN, Ward A, Gilan O, Chan YC, Hienzsch A, Rutkowska A, Werner T, Wagner AJ, Lugo D, Gregory R, Ramirez Molina C, Garton N, Wellaway CR, Jackson S, MacPherson L, Figueiredo M, Stolzenburg S, Bell CC, House C, Dawson SJ, Hawkins ED, Drewes G, Prinjha RK, Rodriguez R, Grandi P, Dawson MA.

Science. 2017 Jun 30;356(6345):1397-1401. doi: 10.1126/science.aal2066. Epub 2017 Jun 15.

19.

Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene.

Lefebure M, Tothill RW, Kruse E, Hawkins ED, Shortt J, Matthews GM, Gregory GP, Martin BP, Kelly MJ, Todorovski I, Doyle MA, Lupat R, Li J, Schroeder J, Wall M, Craig S, Poortinga G, Cameron D, Bywater M, Kats L, Gearhart MD, Bardwell VJ, Dickins RA, Hannan RD, Papenfuss AT, Johnstone RW.

Nat Commun. 2017 Mar 6;8:14581. doi: 10.1038/ncomms14581.

20.

T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments.

Hawkins ED, Duarte D, Akinduro O, Khorshed RA, Passaro D, Nowicka M, Straszkowski L, Scott MK, Rothery S, Ruivo N, Foster K, Waibel M, Johnstone RW, Harrison SJ, Westerman DA, Quach H, Gribben J, Robinson MD, Purton LE, Bonnet D, Lo Celso C.

Nature. 2016 Oct 27;538(7626):518-522. doi: 10.1038/nature19801. Epub 2016 Oct 17.

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