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Items: 11

1.

Neuroligin-2-derived peptide-covered polyamidoamine-based (PAMAM) dendrimers enhance pancreatic β-cells' proliferation and functions.

Munder A, Moskovitz Y, Meir A, Kahremany S, Levy L, Kolitz-Domb M, Cohen G, Shtriker E, Viskind O, Lellouche JP, Senderowitz H, Chessler SD, Korshin EE, Ruthstein S, Gruzman A.

Medchemcomm. 2018 Dec 13;10(2):280-293. doi: 10.1039/c8md00419f. eCollection 2019 Feb 1.

PMID:
30881615
2.

Structurally Simple, Readily Available Peptidomimetic 1-Benzyl-5-methyl-4-( n-octylamino)pyrimidin-2(1 H)-one Exhibited Efficient Cardioprotection in a Myocardial Ischemia (MI) Mouse Model.

Trifonov L, Nudelman V, Zhenin M, Matsree E, Afri M, Schmerling B, Cohen G, Jozwiak K, Weitman M, Korshin E, Senderowitz H, Shainberg A, Hochhauser E, Gruzman A.

J Med Chem. 2018 Dec 27;61(24):11309-11326. doi: 10.1021/acs.jmedchem.8b01471. Epub 2018 Dec 11.

PMID:
30507195
3.

An Expedient Synthesis of CMF-019: (S)-5-Methyl-3-{1-(pentan-3-yl)-2- (thiophen-2-ylmethyl)-1H-benzo[d]imidazole-5-carboxamido}hexanoic Acid, a Potent Apelin Receptor (APJ) Agonist.

Trifonov L, Afri M, Palczewski K, Korshin EE, Gruzman A.

Med Chem. 2018;14(7):688-694. doi: 10.2174/1573406414666180412154952.

PMID:
29651942
4.

Convenient access to readily soluble symmetrical dialkyl-substituted α-oligofurans.

Korshin EE, Leitus GM, Bendikov M.

Org Biomol Chem. 2014 Sep 14;12(34):6661-71. doi: 10.1039/c4ob00898g.

PMID:
25030451
5.

Anti-influenza active and low toxic N-phenyl-substituted β-amidoamidines structurally related to natural antibiotic amidinomycin.

Korshin EE, Zakharova LG, Levin YA, Shulaeva MP, Pozdeev OK.

Bioorg Med Chem Lett. 2013 Apr 15;23(8):2357-61. doi: 10.1016/j.bmcl.2013.02.053. Epub 2013 Feb 22.

PMID:
23489622
6.

Silanol-based pincer Pt(II) complexes: synthesis, structure, and unusual reactivity.

Korshin EE, Leitus G, Shimon LJ, Konstantinovski L, Milstein D.

Inorg Chem. 2008 Aug 18;47(16):7177-89. doi: 10.1021/ic800457u. Epub 2008 Jul 19.

PMID:
18637675
7.

Diels-Alder/thiol-olefin co-oxygenation approach to antimalarials incorporating the 2,3-dioxabicyclo[3.3.1]nonane pharmacophore.

O'Neill PM, Verissimo E, Ward SA, Davies J, Korshin EE, Araujo N, Pugh MD, Cristiano ML, Stocks PA, Bachi MD.

Bioorg Med Chem Lett. 2006 Jun 1;16(11):2991-5. Epub 2006 Mar 9.

PMID:
16527481
8.

Total syntheses of Yingzhaosu A and of its C(14)-epimer including the first evaluation of their antimalarial and cytotoxic activities.

Szpilman AM, Korshin EE, Rozenberg H, Bachi MD.

J Org Chem. 2005 Apr 29;70(9):3618-32.

PMID:
15844999
9.

Design and synthesis of endoperoxide antimalarial prodrug models.

O'Neill PM, Stocks PA, Pugh MD, Araujo NC, Korshin EE, Bickley JF, Ward SA, Bray PG, Pasini E, Davies J, Verissimo E, Bachi MD.

Angew Chem Int Ed Engl. 2004 Aug 13;43(32):4193-7. No abstract available.

PMID:
15307085
10.

Efficient stereoselective alkenylation through a homolytic domino reaction involving a 1,5 sulfur-to-carbon translocation.

Korshin EE, Bilokin YV, Zheng H, Bachi MD.

J Am Chem Soc. 2004 Mar 10;126(9):2708-9.

PMID:
14995181
11.

A short synthesis and biological evaluation of potent and nontoxic antimalarial bridged bicyclic beta-sulfonyl-endoperoxides.

Bachi MD, Korshin EE, Hoos R, Szpilman AM, Ploypradith P, Xie S, Shapiro TA, Posner GH.

J Med Chem. 2003 Jun 5;46(12):2516-33.

PMID:
12773055

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