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Items: 15


Aggregatibacter actinomycetemcomitans LtxA Hijacks Endocytic Trafficking Pathways in Human Lymphocytes.

Lally ET, Boesze-Battaglia K, Dhingra A, Gomez NM, Lora J, Mitchell CH, Giannakakis A, Fahim SA, Benz R, Balashova N.

Pathogens. 2020 Jan 21;9(2). pii: E74. doi: 10.3390/pathogens9020074.


Cytotoxic activity of Kingella kingae RtxA toxin depends on post-translational acylation of lysine residues and cholesterol binding.

Osickova A, Balashova N, Masin J, Sulc M, Roderova J, Wald T, Brown AC, Koufos E, Chang EH, Giannakakis A, Lally ET, Osicka R.

Emerg Microbes Infect. 2018 Nov 7;7(1):178. doi: 10.1038/s41426-018-0179-x.


Membrane localization of the Repeats-in-Toxin (RTX) Leukotoxin (LtxA) produced by Aggregatibacter actinomycetemcomitans.

Brown AC, Boesze-Battaglia K, Balashova NV, Mas Gómez N, Speicher K, Tang HY, Duszyk ME, Lally ET.

PLoS One. 2018 Oct 18;13(10):e0205871. doi: 10.1371/journal.pone.0205871. eCollection 2018.


Aggregatibacter actinomycetemcomitans leukotoxin causes activation of lymphocyte function-associated antigen 1.

Nygren P, Balashova N, Brown AC, Kieba I, Dhingra A, Boesze-Battaglia K, Lally ET.

Cell Microbiol. 2019 Mar;21(3):e12967. doi: 10.1111/cmi.12967. Epub 2018 Nov 28.


Aggregatibacter actinomycetemcomitans Leukotoxin Is Delivered to Host Cells in an LFA-1-Indepdendent Manner When Associated with Outer Membrane Vesicles.

Nice JB, Balashova NV, Kachlany SC, Koufos E, Krueger E, Lally ET, Brown AC.

Toxins (Basel). 2018 Oct 13;10(10). pii: E414. doi: 10.3390/toxins10100414.


Generation of a recombinant Aggregatibacter actinomycetemcomitans RTX toxin in Escherichia coli.

Balashova N, Giannakakis A, Brown AC, Koufos E, Benz R, Arakawa T, Tang HY, Lally ET.

Gene. 2018 Sep 25;672:106-114. doi: 10.1016/j.gene.2018.06.003. Epub 2018 Jun 4.


Trends in Susceptibility to Aggressive Periodontal Disease.

Shahabuddin N, Boesze-Battaglia K, Lally ET.

Int J Dent Oral Health. 2016;2(4). doi: 10.16966/2378-7090.197. Epub 2016 Apr 25.


Aggregatibacter actinomycetemcomitans leukotoxin utilizes a cholesterol recognition/amino acid consensus site for membrane association.

Brown AC, Balashova NV, Epand RM, Epand RF, Bragin A, Kachlany SC, Walters MJ, Du Y, Boesze-Battaglia K, Lally ET.

J Biol Chem. 2013 Aug 9;288(32):23607-21. doi: 10.1074/jbc.M113.486654. Epub 2013 Jun 21.


Aggregatibacter actinomycetemcomitans leukotoxin cytotoxicity occurs through bilayer destabilization.

Brown AC, Boesze-Battaglia K, Du Y, Stefano FP, Kieba IR, Epand RF, Kakalis L, Yeagle PL, Epand RM, Lally ET.

Cell Microbiol. 2012 Jun;14(6):869-81. doi: 10.1111/j.1462-5822.2012.01762.x. Epub 2012 Mar 28.


Aggregatibacter actinomycetemcomitans leukotoxin requires beta-sheets 1 and 2 of the human CD11a beta-propeller for cytotoxicity.

Kieba IR, Fong KP, Tang HY, Hoffman KE, Speicher DW, Klickstein LB, Lally ET.

Cell Microbiol. 2007 Nov;9(11):2689-99. Epub 2007 Jun 24.


Actinobacillus actinomycetemcomitans leukotoxin requires lipid microdomains for target cell cytotoxicity.

Fong KP, Pacheco CM, Otis LL, Baranwal S, Kieba IR, Harrison G, Hersh EV, Boesze-Battaglia K, Lally ET.

Cell Microbiol. 2006 Nov;8(11):1753-67. Epub 2006 Jul 7.


Update on cyclooxygenase inhibitors: has a third COX isoform entered the fray?

Hersh EV, Lally ET, Moore PA.

Curr Med Res Opin. 2005 Aug;21(8):1217-26. Review.


The Microbiology of Early-Onset Periodontitis: Association of Highly Toxic Actinobacillus actinomycetemcomitans Strains With Localized Juvenile Periodontitis.

Zambon JJ, Haraszthy VI, Hariharan G, Lally ET, Demuth DR.

J Periodontol. 1996 Mar;67 Suppl 3S:282-290. doi: 10.1902/jop.1996.67.3s.282.


Structure/Function Aspects of Actinobacillus actinomycetemcomitans Leukotoxin.

Lally ET, Kieba IR, Golub EE, Lear JD, Tanaka JC.

J Periodontol. 1996 Mar;67 Suppl 3S:298-308. doi: 10.1902/jop.1996.67.3s.298.


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