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Int J Environ Res Public Health. 2011 Aug;8(8):3216-31. doi: 10.3390/ijerph8083216. Epub 2011 Aug 3.

Association of moderate coffee intake with self-reported diabetes among urban Brazilians.

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Núcleo de Nutrição, Laboratório de Bioquímica da Nutrição, Faculdade de Ciências da Saúde, Universidade de Brasília, Campus Universitário Darcy Ribeiro-Asa Norte. CEP 70910-900 Brasília-DF, Brazil.


Coffee has been associated with reductions in the risk of non-communicable chronic diseases (NCCD), including diabetes mellitus. Because differences in food habits are recognizable modifying factors in the epidemiology of diabetes, we studied the association of coffee consumption with type-2 diabetes in a sample of the adult population of the Federal District, Brazil. This cross-sectional study was conducted by telephone interview (n = 1,440). A multivariate analysis was run controlling for socio-behavioural variables, obesity and family antecedents of NCCD. A hierarchical linear regression model and a Poisson regression were used to verify association of type-2 diabetes and coffee intake. The independent variables which remained in the final model, following the hierarchical inclusion levels, were: first level-age and marital status; second level-diabetes and dyslipidaemias in antecedents; third level-cigarette smoking, supplement intake, body mass index; and fourth level-coffee intake (≤100 mL/d, 101 to 400 mL/day, and >400 mL/day). After adjusting hierarchically for the confounding variables, consumers of 100 to 400 mL of coffee/day had a 2.7% higher (p = 0.04) prevalence of not having diabetes than those who drank less than 100 mL of coffee/day. Compared to coffee intake of ≤100 mL/day, adults consuming >400 mL of coffee/day showed no statistically significant difference in the prevalence of diabetes. Thus, moderate coffee intake is favourably associated with self-reported type-2 diabetes in the studied population. This is the first study to show a relationship between coffee drinking and diabetes in a Brazilian population.


body mass index; caffeine; chlorogenic acids; coffee intake; diabetes mellitus

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