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Items: 1 to 20 of 27

1.

Sertraline Delivered in Phosphatidylserine Liposomes Is Effective in an Experimental Model of Visceral Leishmaniasis.

Romanelli MM, da Costa-Silva TA, Cunha-Junior E, Dias Ferreira D, Guerra JM, Galisteo AJ Jr, Pinto EG, Barbosa LRS, Torres-Santos EC, Tempone AG.

Front Cell Infect Microbiol. 2019 Oct 29;9:353. doi: 10.3389/fcimb.2019.00353. eCollection 2019.

2.

Evaluation of Novel Chalcone-Thiosemicarbazones Derivatives as Potential Anti-Leishmania amazonensis Agents and Its HSA Binding Studies.

Mendes EP, Goulart CM, Chaves OA, Faiões VDS, Canto-Carvalho MM, Machado GC, Torres-Santos EC, Echevarria A.

Biomolecules. 2019 Oct 23;9(11). pii: E643. doi: 10.3390/biom9110643.

3.

Oral pentamidine-loaded poly(d,l-lactic-co-glycolic) acid nanoparticles: an alternative approach for leishmaniasis treatment.

Valle IV, Machado ME, Araújo CDCB, da Cunha-Junior EF, da Silva Pacheco J, Torres-Santos EC, da Silva LCRP, Cabral LM, do Carmo FA, Sathler PC.

Nanotechnology. 2019 Nov 8;30(45):455102. doi: 10.1088/1361-6528/ab373e. Epub 2019 Jul 31.

PMID:
31365912
4.

Miltefosine-Lopinavir Combination Therapy Against Leishmania infantum Infection: In vitro and in vivo Approaches.

Rebello KM, Andrade-Neto VV, Gomes CRB, de Souza MVN, Branquinha MH, Santos ALS, Torres-Santos EC, d'Avila-Levy CM.

Front Cell Infect Microbiol. 2019 Jun 28;9:229. doi: 10.3389/fcimb.2019.00229. eCollection 2019.

5.

Second-generation pterocarpanquinones: synthesis and antileishmanial activity.

Faiões VDS, da Frota LCRM, Cunha-Junior EF, Barcellos JCF, Da Silva T, Netto CD, Da-Silva SAG, da Silva AJM, Costa PRR, Torres-Santos EC.

J Venom Anim Toxins Incl Trop Dis. 2018 Nov 29;24:35. doi: 10.1186/s40409-018-0174-7. eCollection 2018.

6.

Leishmanicidal Activity of Withanolides from Aureliana Fasciculata var. Fasciculata.

Lima SCM, Pacheco JDS, Marques AM, Veltri ERP, Almeida-Lafetá RC, Figueiredo MR, Kaplan MAC, Torres-Santos EC.

Molecules. 2018 Nov 30;23(12). pii: E3160. doi: 10.3390/molecules23123160.

7.

Anti-Mycobacterium tuberculosis activity of essential oil and 6,7-dehydroroyleanone isolated from leaves of Tetradenia riparia (Hochst.) Codd (Lamiaceae).

Baldin VP, Scodro RBL, Lopes-Ortiz MA, de Almeida AL, Gazim ZC, Ferarrese L, Faiões VDS, Torres-Santos EC, Pires CTA, Caleffi-Ferracioli KR, Siqueira VLD, Cortez DAG, Cardoso RF.

Phytomedicine. 2018 Aug 1;47:34-39. doi: 10.1016/j.phymed.2018.04.043. Epub 2018 Apr 24.

8.

Lopinavir, an HIV-1 peptidase inhibitor, induces alteration on the lipid metabolism of Leishmania amazonensis promastigotes.

Rebello KM, Andrade-Neto VV, Zuma AA, Motta MCM, Gomes CRB, de Souza MVN, Atella GC, Branquinha MH, Santos ALS, Torres-Santos EC, d'Avila-Levy CM.

Parasitology. 2018 Sep;145(10):1304-1310. doi: 10.1017/S0031182018000823. Epub 2018 May 28.

9.

Original antileishmanial hits: Variations around amidoximes.

Tabélé C, Faiões VDS, Grimaud F, Torres-Santos EC, Khoumeri O, Curti C, Vanelle P.

Eur J Med Chem. 2018 Mar 25;148:154-164. doi: 10.1016/j.ejmech.2018.02.029. Epub 2018 Feb 10.

PMID:
29459275
10.

Leishmaniasis treatment: update of possibilities for drug repurposing.

Andrade-Neto VV, Cunha-Junior EF, Dos Santos Faioes V, Pereira TM, Silva RL, Leon LL, Torres-Santos EC.

Front Biosci (Landmark Ed). 2018 Jan 1;23:967-996. Review.

PMID:
28930585
11.

Cyclobenzaprine Raises ROS Levels in Leishmania infantum and Reduces Parasite Burden in Infected Mice.

Cunha-Júnior EF, Andrade-Neto VV, Lima ML, da Costa-Silva TA, Galisteo Junior AJ, Abengózar MA, Barbas C, Rivas L, Almeida-Amaral EE, Tempone AG, Torres-Santos EC.

PLoS Negl Trop Dis. 2017 Jan 3;11(1):e0005281. doi: 10.1371/journal.pntd.0005281. eCollection 2017 Jan.

12.

Evaluation of Chemical Composition and Antileishmanial and Antituberculosis Activities of Essential Oils of Piper Species.

Bernuci KZ, Iwanaga CC, Fernandez-Andrade CM, Lorenzetti FB, Torres-Santos EC, Faiões VD, Gonçalves JE, do Amaral W, Deschamps C, Scodro RB, Cardoso RF, Baldin VP, Cortez DA.

Molecules. 2016 Dec 12;21(12). pii: E1698. doi: 10.3390/molecules21121698.

13.

Evaluation of Chemical Composition and Antileishmanial and Antituberculosis Activities of Essential Oils of Piper Species.

Bernuci KZ, Iwanaga CC, Fernadez-Andrade CM, Lorenzetti FB, Torres-Santos EC, Faiões VD, Gonçalves JE, do Amaral W, Deschamps C, Scodro RB, Cardoso RF, Baldin VP, Cortez DA.

Molecules. 2016 Dec 12;21(12). pii: E1698.

14.

Antileishmanial Activity of Ezetimibe: Inhibition of Sterol Biosynthesis, In Vitro Synergy with Azoles, and Efficacy in Experimental Cutaneous Leishmaniasis.

Andrade-Neto VV, Cunha-Júnior EF, Canto-Cavalheiro MM, Atella GC, Fernandes TA, Costa PR, Torres-Santos EC.

Antimicrob Agents Chemother. 2016 Oct 21;60(11):6844-6852. doi: 10.1128/AAC.01545-16. Print 2016 Nov.

15.

Preclinical Studies Evaluating Subacute Toxicity and Therapeutic Efficacy of LQB-118 in Experimental Visceral Leishmaniasis.

Cunha-Júnior EF, Martins TM, Canto-Cavalheiro MM, Marques PR, Portari EA, Coelho MG, Netto CD, Costa PR, Sabino KC, Torres-Santos EC.

Antimicrob Agents Chemother. 2016 May 23;60(6):3794-801. doi: 10.1128/AAC.01787-15. Print 2016 Jun.

16.

Imipramine alters the sterol profile in Leishmania amazonensis and increases its sensitivity to miconazole.

Andrade-Neto VV, Pereira TM, Canto-Cavalheiro Md, Torres-Santos EC.

Parasit Vectors. 2016 Mar 31;9:183. doi: 10.1186/s13071-016-1467-8.

17.

Novel 3,4-methylenedioxyde-6-X-benzaldehyde-thiosemicarbazones: Synthesis and antileishmanial effects against Leishmania amazonensis.

de Melos JL, Torres-Santos EC, Faiões Vdos S, Del Cistia Cde N, Sant'Anna CM, Rodrigues-Santos CE, Echevarria A.

Eur J Med Chem. 2015 Oct 20;103:409-17. doi: 10.1016/j.ejmech.2015.09.009. Epub 2015 Sep 8.

PMID:
26375353
18.

Oral effectiveness of PMIC4, a novel hydroxyethylpiperazine analogue, in Leishmania amazonensis.

Vasconcelos MF, Cunha-Júnior EF, Andrade-Neto VV, Siqueira LM, d'Avila-Levy CM, Moreth M, Cunico W, Souza MV, Gomes CR, Torres-Santos EC.

Int J Parasitol Drugs Drug Resist. 2014 Nov 8;4(3):210-3. doi: 10.1016/j.ijpddr.2014.10.005. eCollection 2014 Dec.

19.

The new pyrazolyltetrazole derivative MSN20 is effective via oral delivery against cutaneous leishmaniasis.

Faiões Vdos S, Dos Santos MS, Bernardino AM, Cunha-Júnior EF, Canto Cavalheiro MM, Torres-Santos EC.

Antimicrob Agents Chemother. 2014 Oct;58(10):6290-3. doi: 10.1128/AAC.02874-14. Epub 2014 Aug 4.

20.

LQB-118, an orally active pterocarpanquinone, induces selective oxidative stress and apoptosis in Leishmania amazonensis.

Ribeiro GA, Cunha-Júnior EF, Pinheiro RO, da-Silva SA, Canto-Cavalheiro MM, da Silva AJ, Costa PR, Netto CD, Melo RC, Almeida-Amaral EE, Torres-Santos EC.

J Antimicrob Chemother. 2013 Apr;68(4):789-99. doi: 10.1093/jac/dks498. Epub 2013 Jan 3.

PMID:
23288404

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