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Items: 1 to 20 of 27

1.

Synthesis of Isoxazolines by the Electrophilic Chalcogenation of β,γ-Unsaturated Oximes: Fishing Novel Anti-Inflammatory Agents.

Lopes EF, Penteado F, Thurow S, Pinz M, Reis AS, Wilhelm EA, Luchese C, Barcellos T, Dalberto B, Alves D, da Silva MS, Lenardão EJ.

J Org Chem. 2019 Oct 4;84(19):12452-12462. doi: 10.1021/acs.joc.9b01754. Epub 2019 Sep 25.

PMID:
31509698
2.

Synthesis of chitosan derivatives with organoselenium and organosulfur compounds: Characterization, antimicrobial properties and application as biomaterials.

Gularte MS, Anghinoni JM, Abenante L, Voss GT, de Oliveira RL, Vaucher RA, Luchese C, Wilhelm EA, Lenardão EJ, Fajardo AR.

Carbohydr Polym. 2019 Sep 1;219:240-250. doi: 10.1016/j.carbpol.2019.05.040. Epub 2019 May 11.

PMID:
31151522
3.

3-(4-Chlorophenylselanyl)-1-methyl-1H-indole promotes recovery of neuropathic pain and depressive-like behavior induced by partial constriction of the sciatic nerve in mice.

Birmann PT, Sousa FSS, Domingues M, Brüning CA, Vieira BM, Lenardão EJ, Savegnago L.

J Trace Elem Med Biol. 2019 Jul;54:126-133. doi: 10.1016/j.jtemb.2019.04.014. Epub 2019 Apr 24.

PMID:
31109602
4.

Regioselective Synthesis of 1-Sulfanyl- and 1-Selanylindolizines.

Penteado F, Gomes CS, Perin G, Garcia CS, Bortolatto CF, Brüning CA, Lenardão EJ.

J Org Chem. 2019 Jun 7;84(11):7189-7198. doi: 10.1021/acs.joc.9b00871. Epub 2019 May 14.

PMID:
31046283
5.

α-Keto Acids: Acylating Agents in Organic Synthesis.

Penteado F, Lopes EF, Alves D, Perin G, Jacob RG, Lenardão EJ.

Chem Rev. 2019 Apr 16. doi: 10.1021/acs.chemrev.8b00782. [Epub ahead of print]

PMID:
30990680
6.

Effects of a selanylimidazopyridine on the acute restraint stress-induced depressive- and anxiety-like behaviors and biological changes in mice.

Domingues M, Casaril AM, Birmann PT, Bampi SR, Lourenço DA, Vieira BM, Dapper LH, Lenardão EJ, Sonego M, Collares T, Seixas FK, Brüning CA, Savegnago L.

Behav Brain Res. 2019 Jul 2;366:96-107. doi: 10.1016/j.bbr.2019.03.021. Epub 2019 Mar 12.

PMID:
30877027
7.

NMR chiral discrimination of chalcogen containing secondary alcohols.

Marques NBG, Jacob RG, Perin G, Lenardão EJ, Alves D, Silva MS.

Chirality. 2019 Jan;31(1):41-51. doi: 10.1002/chir.23030. Epub 2018 Nov 15.

PMID:
30431670
8.

Selanylimidazopyridine Prevents Lipopolysaccharide-Induced Depressive-Like Behavior in Mice by Targeting Neurotrophins and Inflammatory/Oxidative Mediators.

Domingues M, Casaril AM, Birmann PT, Lourenço DA, Vieira B, Begnini K, Lenardão EJ, Collares T, Seixas FK, Savegnago L.

Front Neurosci. 2018 Jul 19;12:486. doi: 10.3389/fnins.2018.00486. eCollection 2018.

9.

Ultrasound-enhanced Ag-catalyzed decarboxylative coupling between α-keto acids and disulfides for the synthesis of thioesters.

Abenante L, Penteado F, Vieira MM, Perin G, Alves D, Lenardão EJ.

Ultrason Sonochem. 2018 Dec;49:41-46. doi: 10.1016/j.ultsonch.2018.07.014. Epub 2018 Jul 17.

PMID:
30060985
10.

3-(4-Chlorophenylselanyl)-1-methyl-1H-indole, a new selenium compound elicits an antinociceptive and anti-inflammatory effect in mice.

Birmann PT, Sousa FSS, de Oliveira DH, Domingues M, Vieira BM, Lenardão EJ, Savegnago L.

Eur J Pharmacol. 2018 May 15;827:71-79. doi: 10.1016/j.ejphar.2018.03.005. Epub 2018 Mar 10.

PMID:
29535001
11.

Copper Catalysis and Organocatalysis Showing the Way: Synthesis of Selenium-Containing Highly Functionalized 1,2,3-Triazoles.

Alves D, Goldani B, Lenardão EJ, Perin G, Schumacher RF, Paixão MW.

Chem Rec. 2018 May;18(5):527-542. doi: 10.1002/tcr.201700058. Epub 2017 Dec 13. Review.

PMID:
29235236
12.

Selenium-containing indolyl compounds: Kinetics of reaction with inflammation-associated oxidants and protective effect against oxidation of extracellular matrix proteins.

Casaril AM, Ignasiak MT, Chuang CY, Vieira B, Padilha NB, Carroll L, Lenardão EJ, Savegnago L, Davies MJ.

Free Radic Biol Med. 2017 Dec;113:395-405. doi: 10.1016/j.freeradbiomed.2017.10.344. Epub 2017 Oct 18.

13.

Synthesis, Antimicrobial, and Antioxidant Activities of Chalcogen-Containing Nitrone Derivatives from (R)-citronellal.

Ferraz MC, Mano RA, Oliveira DH, Maia DSV, Silva WP, Savegnago L, Lenardão EJ, Jacob RG.

Medicines (Basel). 2017 Jun 10;4(2). pii: E39. doi: 10.3390/medicines4020039.

14.

Synthesis of Terminal Ethynyl Aryl Selenides and Sulfides Based on the Retro-Favorskii Reaction of Hydroxypropargyl Precursors.

Lopes EF, Dalberto BT, Perin G, Alves D, Barcellos T, Lenardão EJ.

Chemistry. 2017 Oct 4;23(55):13760-13765. doi: 10.1002/chem.201702493. Epub 2017 Aug 30.

PMID:
28763120
15.

Ultrasound-promoted copper-catalyzed synthesis of bis-arylselanyl chrysin derivatives with boosted antioxidant and anticancer activities.

Fonseca SF, Padilha NB, Thurow S, Roehrs JA, Savegnago L, de Souza MN, Fronza MG, Collares T, Buss J, Seixas FK, Alves D, Lenardão EJ.

Ultrason Sonochem. 2017 Nov;39:827-836. doi: 10.1016/j.ultsonch.2017.06.007. Epub 2017 Jun 13.

PMID:
28733012
16.

Antidepressant-like effect of a new selenium-containing compound is accompanied by a reduction of neuroinflammation and oxidative stress in lipopolysaccharide-challenged mice.

Casaril AM, Domingues M, Fronza M, Vieira B, Begnini K, Lenardão EJ, Seixas FK, Collares T, Nogueira CW, Savegnago L.

J Psychopharmacol. 2017 Sep;31(9):1263-1273. doi: 10.1177/0269881117711713. Epub 2017 Jun 29.

PMID:
28661258
17.

Glycerol as Precursor of Organoselanyl and Organotellanyl Alkynes.

Lenardão EJ, Borges EL, Stach G, Soares LK, Alves D, Schumacher RF, Bagnoli L, Marini F, Perin G.

Molecules. 2017 Mar 2;22(3). pii: E391. doi: 10.3390/molecules22030391.

18.

Green Hydroselenation of Aryl Alkynes: Divinyl Selenides as a Precursor of Resveratrol.

Perin G, Barcellos AM, Luz EQ, Borges EL, Jacob RG, Lenardão EJ, Sancineto L, Santi C.

Molecules. 2017 Feb 20;22(2). pii: E327. doi: 10.3390/molecules22020327.

19.

Reduction of Selenoamides to Amines Using SmI2-H2O.

Thurow S, Lenardão EJ, Just-Baringo X, Procter DJ.

Org Lett. 2017 Jan 6;19(1):50-53. doi: 10.1021/acs.orglett.6b03325. Epub 2016 Dec 9.

PMID:
27935310
20.

Water and Aqueous Mixtures as Convenient Alternative Media for Organoselenium Chemistry.

Santi C, Jacob RG, Monti B, Bagnoli L, Sancineto L, Lenardão EJ.

Molecules. 2016 Nov 6;21(11). pii: E1482. Review.

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