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Items: 11

1.

The 3S Enantiomer Drives Enolase Inhibitory Activity in SF2312 and Its Analogues.

Pisaneschi F, Lin YH, Leonard PG, Satani N, Yan VC, Hammoudi N, Raghavan S, Link TM, K Georgiou D, Czako B, Muller FL.

Molecules. 2019 Jul 9;24(13). pii: E2510. doi: 10.3390/molecules24132510.

2.

A chemical chaperone improves muscle function in mice with a RyR1 mutation.

Lee CS, Hanna AD, Wang H, Dagnino-Acosta A, Joshi AD, Knoblauch M, Xia Y, Georgiou DK, Xu J, Long C, Amano H, Reynolds C, Dong K, Martin JC, Lagor WR, Rodney GG, Sahin E, Sewry C, Hamilton SL.

Nat Commun. 2017 Mar 24;8:14659. doi: 10.1038/ncomms14659.

3.

ENOblock Does Not Inhibit the Activity of the Glycolytic Enzyme Enolase.

Satani N, Lin YH, Hammoudi N, Raghavan S, Georgiou DK, Muller FL.

PLoS One. 2016 Dec 28;11(12):e0168739. doi: 10.1371/journal.pone.0168739. eCollection 2016.

4.

Ca2+ Binding/Permeation via Calcium Channel, CaV1.1, Regulates the Intracellular Distribution of the Fatty Acid Transport Protein, CD36, and Fatty Acid Metabolism.

Georgiou DK, Dagnino-Acosta A, Lee CS, Griffin DM, Wang H, Lagor WR, Pautler RG, Dirksen RT, Hamilton SL.

J Biol Chem. 2015 Sep 25;290(39):23751-65. doi: 10.1074/jbc.M115.643544. Epub 2015 Aug 5.

5.

Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function.

Lee CS, Dagnino-Acosta A, Yarotskyy V, Hanna A, Lyfenko A, Knoblauch M, Georgiou DK, Poché RA, Swank MW, Long C, Ismailov II, Lanner J, Tran T, Dong K, Rodney GG, Dickinson ME, Beeton C, Zhang P, Dirksen RT, Hamilton SL.

Skelet Muscle. 2015 Jan 29;5:4. doi: 10.1186/s13395-014-0027-1. eCollection 2015.

6.

Ligands for FKBP12 increase Ca2+ influx and protein synthesis to improve skeletal muscle function.

Lee CS, Georgiou DK, Dagnino-Acosta A, Xu J, Ismailov II, Knoblauch M, Monroe TO, Ji R, Hanna AD, Joshi AD, Long C, Oakes J, Tran T, Corona BT, Lorca S, Ingalls CP, Narkar VA, Lanner JT, Bayle JH, Durham WJ, Hamilton SL.

J Biol Chem. 2014 Sep 12;289(37):25556-70. doi: 10.1074/jbc.M114.586289. Epub 2014 Jul 22.

7.

AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation.

Lanner JT, Georgiou DK, Dagnino-Acosta A, Ainbinder A, Cheng Q, Joshi AD, Chen Z, Yarotskyy V, Oakes JM, Lee CS, Monroe TO, Santillan A, Dong K, Goodyear L, Ismailov II, Rodney GG, Dirksen RT, Hamilton SL.

Nat Med. 2012 Jan 8;18(2):244-51. doi: 10.1038/nm.2598.

8.

Ryanodine receptors: structure, expression, molecular details, and function in calcium release.

Lanner JT, Georgiou DK, Joshi AD, Hamilton SL.

Cold Spring Harb Perspect Biol. 2010 Nov;2(11):a003996. doi: 10.1101/cshperspect.a003996. Epub 2010 Oct 20. Review.

9.

Determinants in CaV1 channels that regulate the Ca2+ sensitivity of bound calmodulin.

Halling DB, Georgiou DK, Black DJ, Yang G, Fallon JL, Quiocho FA, Pedersen SE, Hamilton SL.

J Biol Chem. 2009 Jul 24;284(30):20041-51. doi: 10.1074/jbc.M109.013326. Epub 2009 May 27.

10.

A fast response mechanism for insulin storage in crystals may involve kink generation by association of 2D clusters.

Georgiou DK, Vekilov PG.

Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1681-6. Epub 2006 Jan 30.

11.

Capillarity effects on crystallization kinetics: insulin.

Reviakine I, Georgiou DK, Vekilov PG.

J Am Chem Soc. 2003 Sep 24;125(38):11684-93.

PMID:
13129373

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