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Items: 1 to 20 of 261

1.

Letter by Weingärtner et al Regarding Article, "Ezetimibe Lipid-Lowering Trial on Prevention of Atherosclerotic Cardiovascular Disease in 75 or Older (EWTOPIA 75): A Randomized, Controlled Trial".

Weingärtner O, Sijbrands E, Lütjohann D.

Circulation. 2020 Feb 11;141(6):e65-e66. doi: 10.1161/CIRCULATIONAHA.119.043726. Epub 2020 Feb 10. No abstract available.

PMID:
32078427
2.

Optimizing Clinical Cardiovascular Outcomes by a Personalized Approach to Add Ezetimibe to a Statin.

Weingärtner O, Sijbrands EJG, Lütjohann D.

J Am Coll Cardiol. 2020 Jan 7;75(1):128. doi: 10.1016/j.jacc.2019.08.1072. No abstract available.

PMID:
31918825
3.

Interpreting the Benefit of Simvastatin-Ezetimibe in Patients 75 Years or Older.

Weingärtner O, Sijbrands EJG, Lütjohann D.

JAMA Cardiol. 2020 Jan 2. doi: 10.1001/jamacardio.2019.5197. [Epub ahead of print] No abstract available.

PMID:
31895451
4.

Three-dimensional spatially resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progression.

Segovia-Miranda F, Morales-Navarrete H, Kücken M, Moser V, Seifert S, Repnik U, Rost F, Brosch M, Hendricks A, Hinz S, Röcken C, Lütjohann D, Kalaidzidis Y, Schafmayer C, Brusch L, Hampe J, Zerial M.

Nat Med. 2019 Dec;25(12):1885-1893. doi: 10.1038/s41591-019-0660-7. Epub 2019 Dec 2.

PMID:
31792455
5.

Levels of 7alpha-hydroxycholesterol and/or 7alpha-hydroxy-4-cholest-3-one are the optimal biochemical markers for the evaluation of treatment of cerebrotendinous xanthomatosis.

Lütjohann D, Stellaard F, Björkhem I.

J Neurol. 2020 Feb;267(2):572-573. doi: 10.1007/s00415-019-09650-0. Epub 2019 Nov 28. No abstract available.

PMID:
31781930
6.

Edible seaweed-derived constituents: an undisclosed source of neuroprotective compounds.

Schepers M, Martens N, Tiane A, Vanbrabant K, Liu HB, Lütjohann D, Mulder M, Vanmierlo T.

Neural Regen Res. 2020 May;15(5):790-795. doi: 10.4103/1673-5374.268894. Review.

7.

Estimating fetal cholesterol synthesis rates by cord blood analysis in intrauterine growth restriction and normally grown fetuses.

Pecks U, Bornemann V, Klein A, Segger L, Maass N, Alkatout I, Eckmann-Scholz C, Elessawy M, Lütjohann D.

Lipids Health Dis. 2019 Oct 25;18(1):185. doi: 10.1186/s12944-019-1117-1.

8.

Rare dyslipidaemias, from phenotype to genotype to management: a European Atherosclerosis Society task force consensus statement.

Hegele RA, Borén J, Ginsberg HN, Arca M, Averna M, Binder CJ, Calabresi L, Chapman MJ, Cuchel M, von Eckardstein A, Frikke-Schmidt R, Gaudet D, Hovingh GK, Kronenberg F, Lütjohann D, Parhofer KG, Raal FJ, Ray KK, Remaley AT, Stock JK, Stroes ES, Tokgözoğlu L, Catapano AL.

Lancet Diabetes Endocrinol. 2020 Jan;8(1):50-67. doi: 10.1016/S2213-8587(19)30264-5. Epub 2019 Sep 30. Review.

PMID:
31582260
9.

Serum Concentration of Plant Sterol Oxidation Products (POP) Compared to Cholesterol Oxidation Products (COP) after Intake of Oxidized Plant Sterols: A Randomised, Placebo-Controlled, Double-Blind Dose‒Response Pilot Study.

Lin Y, Koppenol WP, Knol D, Vermeer MA, Hiemstra H, Friedrichs S, Lütjohann D, Trautwein EA.

Nutrients. 2019 Sep 30;11(10). pii: E2319. doi: 10.3390/nu11102319.

10.

Need to individualise cholesterol-lowering therapy.

Lütjohann D, Weingärtner O.

Heart. 2019 Aug;105(16):1291-1292. doi: 10.1136/heartjnl-2019-315376. No abstract available.

PMID:
31350368
11.

In vitro effects of sitosterol and sitostanol on mitochondrial respiration in human brown adipocytes, myotubes and hepatocytes.

Nascimento EBM, Konings M, Schaart G, Groen AK, Lütjohann D, van Marken Lichtenbelt WD, Schrauwen P, Plat J.

Eur J Nutr. 2019 Jul 17. doi: 10.1007/s00394-019-02052-y. [Epub ahead of print]

PMID:
31317217
12.

Besnoitia besnoiti infection alters both endogenous cholesterol de novo synthesis and exogenous LDL uptake in host endothelial cells.

Silva LMR, Lütjohann D, Hamid P, Velasquez ZD, Kerner K, Larrazabal C, Failing K, Hermosilla C, Taubert A.

Sci Rep. 2019 Apr 30;9(1):6650. doi: 10.1038/s41598-019-43153-2.

13.

Low serum lathosterol levels associate with fatal cardiovascular disease and excess all-cause mortality: a prospective cohort study.

Weingärtner O, Lütjohann D, Meyer S, Fuhrmann A, Cremers B, Seiler-Mußler S, Schött HF, Kerksiek A, Friedrichs S, Ulbricht U, Zawada A, Laufs U, Schulze PC, Scheller B, Fliser D, Böhm M, Sijbrands E, Heine GH.

Clin Res Cardiol. 2019 Dec;108(12):1381-1385. doi: 10.1007/s00392-019-01474-2. Epub 2019 Apr 4.

PMID:
30949753
14.

First international descriptive and interventional survey for cholesterol and non-cholesterol sterol determination by gas- and liquid-chromatography-Urgent need for harmonisation of analytical methods.

Lütjohann D, Björkhem I, Friedrichs S, Kerksiek A, Lövgren-Sandblom A, Geilenkeuser WJ, Ahrends R, Andrade I, Ansorena D, Astiasarán I, Baila-Rueda L, Barriuso B, Becker S, Bretillon L, Browne RW, Caccia C, Ceglarek U, Cenarro A, Crick PJ, Fauler G, Garcia-Llatas G, Gray R, Griffiths WJ, Gylling H, Harding S, Helmschrodt C, Iuliano L, Janssen HG, Jones P, Kaipiainen L, Kannenberg F, Lagarda MJ, Leoni V, Lottenberg AM, MacKay DS, Matysik S, McDonald J, Menendez-Carreño M, Myrie SB, Sutti Nunes V, Ostlund RE, Polisecki E, Ramos F, Rideout TC, Schaefer EJ, Schmitz G, Wang Y, Zerbinati C, Diczfalusy U, Schött HF.

J Steroid Biochem Mol Biol. 2019 Jun;190:115-125. doi: 10.1016/j.jsbmb.2019.03.025. Epub 2019 Mar 30.

15.

Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer's disease mouse model.

Bogie J, Hoeks C, Schepers M, Tiane A, Cuypers A, Leijten F, Chintapakorn Y, Suttiyut T, Pornpakakul S, Struik D, Kerksiek A, Liu HB, Hellings N, Martinez-Martinez P, Jonker JW, Dewachter I, Sijbrands E, Walter J, Hendriks J, Groen A, Staels B, Lütjohann D, Vanmierlo T, Mulder M.

Sci Rep. 2019 Mar 20;9(1):4908. doi: 10.1038/s41598-019-41399-4.

16.

The emerging concept of "individualized cholesterol-lowering therapy": A change in paradigm.

Lütjohann D, Stellaard F, Mulder MT, Sijbrands EJG, Weingärtner O.

Pharmacol Ther. 2019 Jul;199:111-116. doi: 10.1016/j.pharmthera.2019.03.004. Epub 2019 Mar 12. Review.

PMID:
30877023
17.

Hydroxypropyl-Beta-Cyclodextrin Reduces Inflammatory Signaling from Monocytes: Possible Implications for Suppression of HIV Chronic Immune Activation.

Matassoli FL, Leão IC, Bezerra BB, Pollard RB, Lütjohann D, Hildreth JEK, Arruda LB.

mSphere. 2018 Nov 7;3(6). pii: e00497-18. doi: 10.1128/mSphere.00497-18.

18.

Bi-allelic Mutations in LSS, Encoding Lanosterol Synthase, Cause Autosomal-Recessive Hypotrichosis Simplex.

Romano MT, Tafazzoli A, Mattern M, Sivalingam S, Wolf S, Rupp A, Thiele H, Altmüller J, Nürnberg P, Ellwanger J, Gambon R, Baumer A, Kohlschmidt N, Metze D, Holdenrieder S, Paus R, Lütjohann D, Frank J, Geyer M, Bertolini M, Kokordelis P, Betz RC.

Am J Hum Genet. 2018 Nov 1;103(5):777-785. doi: 10.1016/j.ajhg.2018.09.011. Epub 2018 Oct 25.

19.

Plasma levels of the oxyphytosterol 7α-hydroxycampesterol are associated with cardiovascular events.

Fuhrmann A, Weingärtner O, Meyer S, Cremers B, Seiler-Mußler S, Schött HF, Kerksiek A, Friedrichs S, Ulbricht U, Zawada AM, Laufs U, Scheller B, Fliser D, Schulze PC, Böhm M, Heine GH, Lütjohann D.

Atherosclerosis. 2018 Dec;279:17-22. doi: 10.1016/j.atherosclerosis.2018.10.010. Epub 2018 Oct 17.

PMID:
30366187
20.

Comment on Tauriainen et al.: Serum, liver and bile sitosterol and sitostanol in obese patients with and without NAFLD.

Plat J, Baumgartner S, Houben T, Vreugdenhil ACE, Mensink RP, Lütjohann D, Shiri-Sverdlov R.

Biosci Rep. 2018 Oct 31;38(5). pii: BSR20180505. doi: 10.1042/BSR20180505. Print 2018 Oct 31.

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