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Items: 1 to 20 of 147

1.

Novel Methylated DNA Markers Discriminate Advanced Neoplasia in Pancreatic Cysts: Marker Discovery, Tissue Validation, and Cyst Fluid Testing.

Majumder S, Taylor WR, Yab TC, Berger CK, Dukek BA, Cao X, Foote PH, Wu CW, Mahoney DW, Aslanian HR, Fernández-Del Castillo C, Doyle LA, Farrell JJ, Fisher WE, Lee LS, Lee YN, Park W, Rodrigues C, Gould Rothberg BE, Salem RR, Simeone DM, Urs S, Van Buren G, Smyrk TC, Allawi HT, Lidgard GP, Raimondo M, Chari ST, Kendrick ML, Kisiel JB, Topazian MD, Ahlquist DA.

Am J Gastroenterol. 2019 Jul 15. doi: 10.14309/ajg.0000000000000284. [Epub ahead of print]

PMID:
31306149
2.

Metabolic Regulation of Redox Balance in Cancer.

Purohit V, Simeone DM, Lyssiotis CA.

Cancers (Basel). 2019 Jul 8;11(7). pii: E955. doi: 10.3390/cancers11070955. Review.

3.

Multiplex Enrichment and Detection of Rare KRAS Mutations in Liquid Biopsy Samples using Digital Droplet Pre-Amplification.

Pratt ED, Cowan RW, Manning SL, Qiao E, Cameron H, Schradle K, Simeone DM, Zhen DB.

Anal Chem. 2019 Jun 18;91(12):7516-7523. doi: 10.1021/acs.analchem.8b01605. Epub 2019 May 24.

PMID:
31072097
4.

ATDC is required for the initiation of KRAS-induced pancreatic tumorigenesis.

Wang L, Yang H, Zamperone A, Diolaiti D, Palmbos PL, Abel EV, Purohit V, Dolgalev I, Rhim AD, Ljungman M, Hadju CH, Halbrook CJ, Bar-Sagi D, di Magliano MP, Crawford HC, Simeone DM.

Genes Dev. 2019 Jun 1;33(11-12):641-655. doi: 10.1101/gad.323303.118. Epub 2019 May 2.

PMID:
31048544
5.

Pilot Study of Personalized Video Visit Summaries for Patients With Cancer.

Krauss JC, Sahai V, Kirch M, Simeone DM, An L.

JCO Clin Cancer Inform. 2018 Dec;2:1-8. doi: 10.1200/CCI.17.00086.

6.

ATDC mediates a TP63-regulated basal cancer invasive program.

Palmbos PL, Wang Y, Bankhead Iii A, Kelleher AJ, Wang L, Yang H, Ahmet ML, Gumkowski ER, Welling SD, Magnuson B, Leflein J, Lorenzatti Hiles G, Abel EV, Dziubinski ML, Urs S, Day ML, Ljungman ME, Simeone DM.

Oncogene. 2019 May;38(18):3340-3354. doi: 10.1038/s41388-018-0646-9. Epub 2019 Jan 14.

7.

Evaluating Susceptibility to Pancreatic Cancer: ASCO Provisional Clinical Opinion.

Stoffel EM, McKernin SE, Brand R, Canto M, Goggins M, Moravek C, Nagarajan A, Petersen GM, Simeone DM, Yurgelun M, Khorana AA.

J Clin Oncol. 2019 Jan 10;37(2):153-164. doi: 10.1200/JCO.18.01489. Epub 2018 Nov 20.

PMID:
30457921
8.

Pancreatic Microtumors: A Novel 3D Ex Vivo Testing Platform.

Goodwin ML, Urs SK, Simeone DM.

Methods Mol Biol. 2019;1882:73-80. doi: 10.1007/978-1-4939-8879-2_7.

PMID:
30378045
9.

3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer.

Wang Y, Day ML, Simeone DM, Palmbos PL.

J Vis Exp. 2018 Sep 13;(139). doi: 10.3791/58345.

PMID:
30272657
10.

Cyclooxygenase-2 Influences Response to Cotargeting of MEK and CDK4/6 in a Subpopulation of Pancreatic Cancers.

Maust JD, Frankowski-McGregor CL, Bankhead A 3rd, Simeone DM, Sebolt-Leopold JS.

Mol Cancer Ther. 2018 Dec;17(12):2495-2506. doi: 10.1158/1535-7163.MCT-18-0082. Epub 2018 Sep 25.

PMID:
30254182
11.

Scalable Multiplexed Drug-Combination Screening Platforms Using 3D Microtumor Model for Precision Medicine.

Zhang Z, Chen YC, Urs S, Chen L, Simeone DM, Yoon E.

Small. 2018 Oct;14(42):e1703617. doi: 10.1002/smll.201703617. Epub 2018 Sep 21.

PMID:
30239130
12.

HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties.

Abel EV, Goto M, Magnuson B, Abraham S, Ramanathan N, Hotaling E, Alaniz AA, Kumar-Sinha C, Dziubinski ML, Urs S, Wang L, Shi J, Waghray M, Ljungman M, Crawford HC, Simeone DM.

Elife. 2018 Aug 3;7. pii: e33947. doi: 10.7554/eLife.33947.

13.

SHP2 Inhibition Prevents Adaptive Resistance to MEK Inhibitors in Multiple Cancer Models.

Fedele C, Ran H, Diskin B, Wei W, Jen J, Geer MJ, Araki K, Ozerdem U, Simeone DM, Miller G, Neel BG, Tang KH.

Cancer Discov. 2018 Oct;8(10):1237-1249. doi: 10.1158/2159-8290.CD-18-0444. Epub 2018 Jul 25.

PMID:
30045908
14.

HIF1-alpha Regulates Acinar Cell Function and Response to Injury in Mouse Pancreas.

Park MJ, Iyer S, Xue X, Bragazzi Cunha J, Gu S, Moons D, Pipe SW, Williams JA, Simeone DM, Shah YM, Omary MB.

Gastroenterology. 2018 May;154(6):1630-1634.e3. doi: 10.1053/j.gastro.2018.01.037. Epub 2018 Feb 1.

15.

An academic career in global surgery: a position paper from the Society of University Surgeons Committee on Academic Global Surgery.

Krishnaswami S, Stephens CQ, Yang GP, Nwomeh BC, Swaroop M, Nadler EP, Holterman AX, Simeone DM, Kingham TP, Merchant N, Orloff SL.

Surgery. 2018 Apr;163(4):954-960. doi: 10.1016/j.surg.2017.10.019. Epub 2017 Dec 15. Review.

PMID:
29254606
16.

Usp9x Promotes Survival in Human Pancreatic Cancer and Its Inhibition Suppresses Pancreatic Ductal Adenocarcinoma In Vivo Tumor Growth.

Pal A, Dziubinski M, Di Magliano MP, Simeone DM, Owens S, Thomas D, Peterson L, Potu H, Talpaz M, Donato NJ.

Neoplasia. 2018 Feb;20(2):152-164. doi: 10.1016/j.neo.2017.11.007. Epub 2017 Dec 14.

17.

High-Throughput Microfluidic Labyrinth for the Label-free Isolation of Circulating Tumor Cells.

Lin E, Rivera-Báez L, Fouladdel S, Yoon HJ, Guthrie S, Wieger J, Deol Y, Keller E, Sahai V, Simeone DM, Burness ML, Azizi E, Wicha MS, Nagrath S.

Cell Syst. 2017 Sep 27;5(3):295-304.e4. doi: 10.1016/j.cels.2017.08.012. Epub 2017 Sep 20.

18.

Microfluidic continuum sorting of sub-populations of tumor cells via surface antibody expression levels.

Jack R, Hussain K, Rodrigues D, Zeinali M, Azizi E, Wicha M, Simeone DM, Nagrath S.

Lab Chip. 2017 Mar 29;17(7):1349-1358. doi: 10.1039/c6lc01496h.

PMID:
28294230
19.

A Gastric Glycoform of MUC5AC Is a Biomarker of Mucinous Cysts of the Pancreas.

Sinha J, Cao Z, Dai J, Tang H, Partyka K, Hostetter G, Simeone DM, Feng Z, Allen PJ, Brand RE, Haab BB.

PLoS One. 2016 Dec 19;11(12):e0167070. doi: 10.1371/journal.pone.0167070. eCollection 2016.

20.

Tissue Classification Using Optical Spectroscopy Accurately Differentiates Cancer and Chronic Pancreatitis.

Wilson RH, Chandra M, Scheiman JM, Lee SY, Lee OE, McKenna BJ, Simeone DM, Taylor JM, Mycek MA.

Pancreas. 2017 Feb;46(2):244-251. doi: 10.1097/MPA.0000000000000732.

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