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Items: 1 to 20 of 72

1.

The Plasma Factor XIII Heterotetrameric Complex Structure: Unexpected Unequal Pairing within a Symmetric Complex.

Singh S, Nazabal A, Kaniyappan S, Pellequer JL, Wolberg AS, Imhof D, Oldenburg J, Biswas A.

Biomolecules. 2019 Nov 21;9(12). pii: E765. doi: 10.3390/biom9120765.

2.

Structural insights into heme binding to IL-36α proinflammatory cytokine.

Wißbrock A, Goradia NB, Kumar A, Paul George AA, Kühl T, Bellstedt P, Ramachandran R, Hoffmann P, Galler K, Popp J, Neugebauer U, Hampel K, Zimmermann B, Adam S, Wiendl M, Krönke G, Hamza I, Heinemann SH, Frey S, Hueber AJ, Ohlenschläger O, Imhof D.

Sci Rep. 2019 Nov 15;9(1):16893. doi: 10.1038/s41598-019-53231-0.

3.

Structure functional insights into calcium binding during the activation of coagulation factor XIII A.

Singh S, Dodt J, Volkers P, Hethershaw E, Philippou H, Ivaskevicius V, Imhof D, Oldenburg J, Biswas A.

Sci Rep. 2019 Aug 5;9(1):11324. doi: 10.1038/s41598-019-47815-z.

4.

NMR experiments on the transient interaction of the intrinsically disordered N-terminal peptide of cystathionine-β-synthase with heme.

Kumar A, Bellstedt P, Wiedemann C, Wißbrock A, Imhof D, Ramachandran R, Ohlenschläger O.

J Magn Reson. 2019 Nov;308:106561. doi: 10.1016/j.jmr.2019.07.048. Epub 2019 Jul 16.

PMID:
31345774
5.

Effect of Conformational Diversity on the Bioactivity of µ-Conotoxin PIIIA Disulfide Isomers.

Paul George AA, Heimer P, Leipold E, Schmitz T, Kaufmann D, Tietze D, Heinemann SH, Imhof D.

Mar Drugs. 2019 Jul 2;17(7). pii: E390. doi: 10.3390/md17070390.

6.

Coagulation Factor XIIIa Inhibitor Tridegin: On the Role of Disulfide Bonds for Folding, Stability, and Function.

Bäuml CA, Schmitz T, Paul George AA, Sudarsanam M, Hardes K, Steinmetzer T, Holle LA, Wolberg AS, Pötzsch B, Oldenburg J, Biswas A, Imhof D.

J Med Chem. 2019 Apr 11;62(7):3513-3523. doi: 10.1021/acs.jmedchem.8b01982. Epub 2019 Mar 21.

PMID:
30852892
7.

1H, 13C, and 15N resonance assignments of the cytokine interleukin-36β isoform-2.

Kumar A, Wißbrock A, Bellstedt P, Lang A, Ramachandran R, Wiedemann C, Imhof D, Ohlenschläger O.

Biomol NMR Assign. 2019 Apr;13(1):155-161. doi: 10.1007/s12104-018-09869-4. Epub 2019 Feb 13.

PMID:
30758717
8.

The molecular basis of transient heme-protein interactions: analysis, concept and implementation.

Wißbrock A, Paul George AA, Brewitz HH, Kühl T, Imhof D.

Biosci Rep. 2019 Jan 30;39(1). pii: BSR20181940. doi: 10.1042/BSR20181940. Print 2019 Jan 31. Review.

9.

Insights into the Folding of Disulfide-Rich μ-Conotoxins.

Paul George AA, Heimer P, Maaß A, Hamaekers J, Hofmann-Apitius M, Biswas A, Imhof D.

ACS Omega. 2018 Oct 31;3(10):12330-12340. doi: 10.1021/acsomega.8b01465. Epub 2018 Oct 1.

10.

Synthesis and Structure Determination of µ-Conotoxin PIIIA Isomers with Different Disulfide Connectivities.

Heimer P, Schmitz T, Bäuml CA, Imhof D.

J Vis Exp. 2018 Oct 2;(140). doi: 10.3791/58368.

PMID:
30346393
11.

Insights into mechanism and functional consequences of heme binding to hemolysin-activating lysine acyltransferase HlyC from Escherichia coli.

Peherstorfer S, Brewitz HH, Paul George AA, Wißbrock A, Adam JM, Schmitt L, Imhof D.

Biochim Biophys Acta Gen Subj. 2018 Sep;1862(9):1964-1972. doi: 10.1016/j.bbagen.2018.06.012. Epub 2018 Jun 15.

PMID:
29908817
12.

Deciphering Specificity Determinants for FR900359-Derived Gq α Inhibitors Based on Computational and Structure-Activity Studies.

Reher R, Kühl T, Annala S, Benkel T, Kaufmann D, Nubbemeyer B, Odhiambo JP, Heimer P, Bäuml CA, Kehraus S, Crüsemann M, Kostenis E, Tietze D, König GM, Imhof D.

ChemMedChem. 2018 Aug 20;13(16):1634-1643. doi: 10.1002/cmdc.201800304. Epub 2018 Jul 3.

PMID:
29873888
13.

Quantification of amino acids and peptides in an ionic liquid based aqueous two-phase system by LC-MS analysis.

Oppermann S, Oppermann C, Böhm M, Kühl T, Imhof D, Kragl U.

AMB Express. 2018 Apr 25;8(1):66. doi: 10.1186/s13568-018-0596-1.

14.

HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130.

Göder A, Emmerich C, Nikolova T, Kiweler N, Schreiber M, Kühl T, Imhof D, Christmann M, Heinzel T, Schneider G, Krämer OH.

Nat Commun. 2018 Feb 22;9(1):764. doi: 10.1038/s41467-018-03096-0.

15.

Heme interaction of the intrinsically disordered N-terminal peptide segment of human cystathionine-β-synthase.

Kumar A, Wißbrock A, Goradia N, Bellstedt P, Ramachandran R, Imhof D, Ohlenschläger O.

Sci Rep. 2018 Feb 6;8(1):2474. doi: 10.1038/s41598-018-20841-z.

16.

Conformational μ-Conotoxin PIIIA Isomers Revisited: Impact of Cysteine Pairing on Disulfide-Bond Assignment and Structure Elucidation.

Heimer P, Tietze AA, Bäuml CA, Resemann A, Mayer FJ, Suckau D, Ohlenschläger O, Tietze D, Imhof D.

Anal Chem. 2018 Mar 6;90(5):3321-3327. doi: 10.1021/acs.analchem.7b04854. Epub 2018 Feb 8.

PMID:
29397705
17.

Lack of beta-arrestin signaling in the absence of active G proteins.

Grundmann M, Merten N, Malfacini D, Inoue A, Preis P, Simon K, Rüttiger N, Ziegler N, Benkel T, Schmitt NK, Ishida S, Müller I, Reher R, Kawakami K, Inoue A, Rick U, Kühl T, Imhof D, Aoki J, König GM, Hoffmann C, Gomeza J, Wess J, Kostenis E.

Nat Commun. 2018 Jan 23;9(1):341. doi: 10.1038/s41467-017-02661-3.

18.

New insights into the mechanism of nickel superoxide degradation from studies of model peptides.

Tietze D, Sartorius J, Koley Seth B, Herr K, Heimer P, Imhof D, Mollenhauer D, Buntkowsky G.

Sci Rep. 2017 Dec 8;7(1):17194. doi: 10.1038/s41598-017-17446-3.

19.

CO-independent modification of K+ channels by tricarbonyldichlororuthenium(II) dimer (CORM-2).

Gessner G, Sahoo N, Swain SM, Hirth G, Schönherr R, Mede R, Westerhausen M, Brewitz HH, Heimer P, Imhof D, Hoshi T, Heinemann SH.

Eur J Pharmacol. 2017 Nov 15;815:33-41. doi: 10.1016/j.ejphar.2017.10.006. Epub 2017 Oct 5.

20.

A Tough Nut to Crack: Intracellular Detection and Quantification of Heme in Malaria Parasites by a Genetically Encoded Protein Sensor.

Wißbrock A, Imhof D.

Chembiochem. 2017 Aug 17;18(16):1561-1564. doi: 10.1002/cbic.201700274. Epub 2017 Jul 5.

PMID:
28547798

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