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Items: 16

1.

Assessment of the higher order structure of Humira®, Remicade®, Avastin®, Rituxan®, Herceptin®, and Enbrel® by 2D-NMR fingerprinting.

Hodgson DJ, Ghasriani H, Aubin Y.

J Pharm Biomed Anal. 2019 Jan 30;163:144-152. doi: 10.1016/j.jpba.2018.09.056. Epub 2018 Oct 1.

PMID:
30296716
2.

Application of 2D-NMR with room temperature NMR probes for the assessment of the higher order structure of filgrastim.

Brinson RG, Ghasriani H, Hodgson DJ, Adams KM, McEwen I, Freedberg DI, Chen K, Keire DA, Aubin Y, Marino JP.

J Pharm Biomed Anal. 2017 Jul 15;141:229-233. doi: 10.1016/j.jpba.2017.03.063. Epub 2017 Apr 4.

3.

Assessment of the structure of pegylated-recombinant protein therapeutics by the NMR fingerprint assay.

Hodgson DJ, Aubin Y.

J Pharm Biomed Anal. 2017 May 10;138:351-356. doi: 10.1016/j.jpba.2017.01.058. Epub 2017 Feb 16.

PMID:
28254519
4.

Precision and robustness of 2D-NMR for structure assessment of filgrastim biosimilars.

Ghasriani H, Hodgson DJ, Brinson RG, McEwen I, Buhse LF, Kozlowski S, Marino JP, Aubin Y, Keire DA.

Nat Biotechnol. 2016 Feb;34(2):139-41. doi: 10.1038/nbt.3474. No abstract available.

5.

Monitoring Effects of Excipients, Formulation Parameters and Mutations on the High Order Structure of Filgrastim by NMR.

Aubin Y, Hodgson DJ, Thach WB, Gingras G, Sauvé S.

Pharm Res. 2015 Oct;32(10):3365-75. doi: 10.1007/s11095-015-1713-3. Epub 2015 Jun 5.

PMID:
26043856
6.

A single N-acetylgalactosamine residue at threonine 106 modifies the dynamics and structure of interferon α2a around the glycosylation site.

Ghasriani H, Belcourt PJ, Sauvé S, Hodgson DJ, Brochu D, Gilbert M, Aubin Y.

J Biol Chem. 2013 Jan 4;288(1):247-54. doi: 10.1074/jbc.M112.413252. Epub 2012 Nov 26.

7.

Stereochemistry of 10-sulfoxidation catalyzed by a soluble Delta9 desaturase.

Tremblay AE, Tan N, Whittle E, Hodgson DJ, Dawson B, Buist PH, Shanklin J.

Org Biomol Chem. 2010 Mar 21;8(6):1322-8. doi: 10.1039/b921753c. Epub 2010 Jan 7.

PMID:
20204203
8.

Assessment of the effects of pH, formulation and deformulation on the conformation of interferon alpha-2 by NMR.

Panjwani N, Hodgson DJ, Sauvé S, Aubin Y.

J Pharm Sci. 2010 Aug;99(8):3334-42. doi: 10.1002/jps.22105.

PMID:
20186942
9.

NMR assignment of the N-terminal TRAF-like RING zinc finger domain of human FLN29.

Sauvé S, Gingras G, Aubin RA, Hodgson DJ, Aubin Y.

Biomol NMR Assign. 2008 Jun;2(1):33-6. doi: 10.1007/s12104-007-9077-1. Epub 2007 Dec 28.

PMID:
19636918
10.

Synthesis of chiral fluorine-tagged reference standards for the (19)F NMR-based stereochemical analysis of sulfoxides at trace analytical levels.

Tremblay AE, Lao KY, Hodgson DJ, Dawson B, Buist PH.

Bioorg Med Chem Lett. 2009 Sep 1;19(17):5146-50. doi: 10.1016/j.bmcl.2009.07.026. Epub 2009 Jul 10.

PMID:
19632835
11.

In vitro enzymatic oxidation of a fluorine-tagged sulfido substrate analogue: a 19F NMR investigation.

Tremblay AE, Buist PH, Hodgson D, Dawson B, Whittle E, Shanklin J.

Magn Reson Chem. 2006 Jun;44(6):629-32.

PMID:
16534835
12.

Quantitation of hydroxylated byproduct formation in a Saccharomyces cerevisiae Delta9 desaturating system.

Carvalho F, Gauthier LT, Hodgson DJ, Dawson B, Buist PH.

Org Biomol Chem. 2005 Nov 7;3(21):3979-83. Epub 2005 Oct 3.

PMID:
16240017
13.

A micromethod for the stereochemical analysis of fatty acid desaturase-mediated sulfoxidation reactions.

Lao KY, Hodgson DJ, Dawson B, Buist PH.

Bioorg Med Chem Lett. 2005 Jun 2;15(11):2799-802.

PMID:
15911257
14.
15.

Iridium luminophore complexes for unimolecular oxygen sensors.

DeRosa MC, Hodgson DJ, Enright GD, Dawson B, Evans CE, Crutchley RJ.

J Am Chem Soc. 2004 Jun 23;126(24):7619-26. Erratum in: J Am Chem Soc. 2004 Aug 25;126(33):10493.

PMID:
15198610
16.

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