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Items: 1 to 20 of 48

1.

Metabolic Reprogramming and Vulnerabilities in Cancer.

Lyssiotis CA, Nagrath D.

Cancers (Basel). 2019 Dec 30;12(1). pii: E90. doi: 10.3390/cancers12010090.

2.

Quantifying Metabolic Transfer Mediated by Extracellular Vesicles Using Exo-MFA: An Integrated Empirical and Computational Platform.

Achreja A, Meurs N, Nagrath D.

Methods Mol Biol. 2020;2088:205-221. doi: 10.1007/978-1-0716-0159-4_10.

PMID:
31893376
3.

Liquid Chromatography Methods for Separation of Polar and Charged Intracellular Metabolites for 13C Metabolic Flux Analysis.

Jaiswal D, Mittal A, Nagrath D, Wangikar PP.

Methods Mol Biol. 2020;2088:33-50. doi: 10.1007/978-1-0716-0159-4_3.

PMID:
31893369
4.

Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts.

Bhagat TD, Von Ahrens D, Dawlaty M, Zou Y, Baddour J, Achreja A, Zhao H, Yang L, Patel B, Kwak C, Choudhary GS, Gordon-Mitchell S, Aluri S, Bhattacharyya S, Sahu S, Bhagat P, Yu Y, Bartenstein M, Giricz O, Suzuki M, Sohal D, Gupta S, Guerrero PA, Batra S, Goggins M, Steidl U, Greally J, Agarwal B, Pradhan K, Banerjee D, Nagrath D, Maitra A, Verma A.

Elife. 2019 Nov 1;8. pii: e50663. doi: 10.7554/eLife.50663.

5.

Reactive Oxygen Species in the Tumor Microenvironment: An Overview.

Weinberg F, Ramnath N, Nagrath D.

Cancers (Basel). 2019 Aug 16;11(8). pii: E1191. doi: 10.3390/cancers11081191. Review.

6.

Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism.

Collin de l'Hortet A, Takeishi K, Guzman-Lepe J, Morita K, Achreja A, Popovic B, Wang Y, Handa K, Mittal A, Meurs N, Zhu Z, Weinberg F, Salomon M, Fox IJ, Deng CX, Nagrath D, Soto-Gutierrez A.

Cell Metab. 2019 Aug 6;30(2):385-401.e9. doi: 10.1016/j.cmet.2019.06.017.

PMID:
31390551
7.

Regulation of protein metabolism in cancer.

Han C, Lu X, Nagrath D.

Mol Cell Oncol. 2018 May 10;5(5):e1285384. doi: 10.1080/23723556.2017.1285384. eCollection 2018.

8.

The key role of extracellular vesicles in the metastatic process.

Zhao H, Achreja A, Iessi E, Logozzi M, Mizzoni D, Di Raimo R, Nagrath D, Fais S.

Biochim Biophys Acta Rev Cancer. 2018 Jan;1869(1):64-77. doi: 10.1016/j.bbcan.2017.11.005. Epub 2017 Nov 24. Review.

9.

Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development.

Xiao ZD, Han L, Lee H, Zhuang L, Zhang Y, Baddour J, Nagrath D, Wood CG, Gu J, Wu X, Liang H, Gan B.

Nat Commun. 2017 Oct 4;8(1):783. doi: 10.1038/s41467-017-00902-z.

10.

Nitric Oxide: The Forgotten Child of Tumor Metabolism.

Salimian Rizi B, Achreja A, Nagrath D.

Trends Cancer. 2017 Sep;3(9):659-672. doi: 10.1016/j.trecan.2017.07.005. Epub 2017 Aug 18. Review.

11.

The role of stromal cancer-associated fibroblasts in pancreatic cancer.

von Ahrens D, Bhagat TD, Nagrath D, Maitra A, Verma A.

J Hematol Oncol. 2017 Mar 28;10(1):76. doi: 10.1186/s13045-017-0448-5. Review.

12.

Glutaminolysis: A Hallmark of Cancer Metabolism.

Yang L, Venneti S, Nagrath D.

Annu Rev Biomed Eng. 2017 Jun 21;19:163-194. doi: 10.1146/annurev-bioeng-071516-044546. Epub 2017 Mar 8. Review.

PMID:
28301735
13.

Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma.

Ju HQ, Ying H, Tian T, Ling J, Fu J, Lu Y, Wu M, Yang L, Achreja A, Chen G, Zhuang Z, Wang H, Nagrath D, Yao J, Hung MC, DePinho RA, Huang P, Xu RH, Chiao PJ.

Nat Commun. 2017 Feb 24;8:14437. doi: 10.1038/ncomms14437.

14.

Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer.

Dey P, Baddour J, Muller F, Wu CC, Wang H, Liao WT, Lan Z, Chen A, Gutschner T, Kang Y, Fleming J, Satani N, Zhao D, Achreja A, Yang L, Lee J, Chang E, Genovese G, Viale A, Ying H, Draetta G, Maitra A, Wang YA, Nagrath D, DePinho RA.

Nature. 2017 Feb 2;542(7639):119-123. doi: 10.1038/nature21052. Epub 2017 Jan 18.

15.

Exo-MFA - A 13C metabolic flux analysis framework to dissect tumor microenvironment-secreted exosome contributions towards cancer cell metabolism.

Achreja A, Zhao H, Yang L, Yun TH, Marini J, Nagrath D.

Metab Eng. 2017 Sep;43(Pt B):156-172. doi: 10.1016/j.ymben.2017.01.001. Epub 2017 Jan 11.

PMID:
28087332
16.

Amplification of USP13 drives ovarian cancer metabolism.

Han C, Yang L, Choi HH, Baddour J, Achreja A, Liu Y, Li Y, Li J, Wan G, Huang C, Ji G, Zhang X, Nagrath D, Lu X.

Nat Commun. 2016 Nov 28;7:13525. doi: 10.1038/ncomms13525.

17.

Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth.

Yang L, Achreja A, Yeung TL, Mangala LS, Jiang D, Han C, Baddour J, Marini JC, Ni J, Nakahara R, Wahlig S, Chiba L, Kim SH, Morse J, Pradeep S, Nagaraja AS, Haemmerle M, Kyunghee N, Derichsweiler M, Plackemeier T, Mercado-Uribe I, Lopez-Berestein G, Moss T, Ram PT, Liu J, Lu X, Mok SC, Sood AK, Nagrath D.

Cell Metab. 2016 Nov 8;24(5):685-700. doi: 10.1016/j.cmet.2016.10.011.

18.

Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism.

Zhao H, Yang L, Baddour J, Achreja A, Bernard V, Moss T, Marini JC, Tudawe T, Seviour EG, San Lucas FA, Alvarez H, Gupta S, Maiti SN, Cooper L, Peehl D, Ram PT, Maitra A, Nagrath D.

Elife. 2016 Feb 27;5:e10250. doi: 10.7554/eLife.10250.

19.

Role of Increased n-acetylaspartate Levels in Cancer.

Zand B, Previs RA, Zacharias NM, Rupaimoole R, Mitamura T, Nagaraja AS, Guindani M, Dalton HJ, Yang L, Baddour J, Achreja A, Hu W, Pecot CV, Ivan C, Wu SY, McCullough CR, Gharpure KM, Shoshan E, Pradeep S, Mangala LS, Rodriguez-Aguayo C, Wang Y, Nick AM, Davies MA, Armaiz-Pena G, Liu J, Lutgendorf SK, Baggerly KA, Eli MB, Lopez-Berestein G, Nagrath D, Bhattacharya PK, Sood AK.

J Natl Cancer Inst. 2016 Jan 26;108(6):djv426. doi: 10.1093/jnci/djv426.

20.

Linking omentum and ovarian cancer: NO.

Rizi BS, Nagrath D.

Oncoscience. 2015 Sep 14;2(10):797-8. eCollection 2015. No abstract available.

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