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Items: 1 to 20 of 38


Estrogen amplifies pre-existing atopy-associated Th2-bias in an experimental asthma model.

Lauzon-Joset JF, Mincham KT, Abad AP, Short BP, Holt PG, Strickland DH, Leffler J.

Clin Exp Allergy. 2019 Nov 30. doi: 10.1111/cea.13544. [Epub ahead of print]


A method for the generation of large numbers of dendritic cells from CD34+ hematopoietic stem cells from cord blood.

Bedke N, Swindle EJ, Molnar C, Holt PG, Strickland DH, Roberts GC, Morris R, Holgate ST, Davies DE, Blume C.

J Immunol Methods. 2019 Nov 9:112703. doi: 10.1016/j.jim.2019.112703. [Epub ahead of print]


Immunoinflammatory responses to febrile lower respiratory infections in infants display uniquely complex/intense transcriptomic profiles.

Jones AC, Anderson D, Galbraith S, Fantino E, Cardenas DG, Read JF, Serralha M, Holt BJ, Strickland DH, Sly PD, Bosco A, Holt PG.

J Allergy Clin Immunol. 2019 Nov;144(5):1411-1413. doi: 10.1016/j.jaci.2019.07.043. Epub 2019 Aug 19. No abstract available.


Progressive increase of FcεRI expression across several PBMC subsets is associated with atopy and atopic asthma within school-aged children.

Leffler J, Read JF, Jones AC, Mok D, Hollams EM, Laing IA, Le Souef PN, Sly PD, Kusel MMH, de Klerk NH, Bosco A, Holt PG, Strickland DH.

Pediatr Allergy Immunol. 2019 Sep;30(6):646-653. doi: 10.1111/pai.13063. Epub 2019 May 22.


Pregnancy Induces a Steady-State Shift in Alveolar Macrophage M1/M2 Phenotype That Is Associated With a Heightened Severity of Influenza Virus Infection: Mechanistic Insight Using Mouse Models.

Lauzon-Joset JF, Scott NM, Mincham KT, Stumbles PA, Holt PG, Strickland DH.

J Infect Dis. 2019 May 5;219(11):1823-1831. doi: 10.1093/infdis/jiy732.


Personalized Transcriptomics Reveals Heterogeneous Immunophenotypes in Children with Viral Bronchiolitis.

Jones AC, Anderson D, Galbraith S, Fantino E, Gutierrez Cardenas D, Read JF, Serralha M, Holt BJ, Strickland DH, Sly PD, Bosco A, Holt PG.

Am J Respir Crit Care Med. 2019 Jun 15;199(12):1537-1549. doi: 10.1164/rccm.201804-0715OC.


Transplacental immune modulation with a bacterial-derived agent protects against allergic airway inflammation.

Mincham KT, Scott NM, Lauzon-Joset JF, Leffler J, Larcombe AN, Stumbles PA, Robertson SA, Pasquali C, Holt PG, Strickland DH.

J Clin Invest. 2018 Nov 1;128(11):4856-4869. doi: 10.1172/JCI122631. Epub 2018 Oct 2.


Atopy-Dependent and Independent Immune Responses in the Heightened Severity of Atopics to Respiratory Viral Infections: Rat Model Studies.

Lauzon-Joset JF, Jones AC, Mincham KT, Thomas JA, Rosenthal LA, Bosco A, Holt PG, Strickland DH.

Front Immunol. 2018 Aug 13;9:1805. doi: 10.3389/fimmu.2018.01805. eCollection 2018.


Basophil counts in PBMC populations during childhood acute wheeze/asthma are associated with future exacerbations.

Leffler J, Jones AC, Hollams EM, Prastanti F, Le Souëf PN, Holt PG, Bosco A, Laing IA, Strickland DH.

J Allergy Clin Immunol. 2018 Nov;142(5):1639-1641.e5. doi: 10.1016/j.jaci.2018.07.003. Epub 2018 Jul 21. No abstract available.


Immunological Processes Driving IgE Sensitisation and Disease Development in Males and Females.

Leffler J, Stumbles PA, Strickland DH.

Int J Mol Sci. 2018 May 23;19(6). pii: E1554. doi: 10.3390/ijms19061554. Review.


Functional differences in airway dendritic cells determine susceptibility to IgE-sensitization.

Leffler J, Mincham KT, Mok D, Blank F, Holt PG, Stumbles PA, Strickland DH.

Immunol Cell Biol. 2018 Mar;96(3):316-329. doi: 10.1111/imcb.12005. Epub 2018 Feb 2.


A pathogenic role for the integrin CD103 in experimental allergic airways disease.

Fear VS, Lai SP, Zosky GR, Perks KL, Gorman S, Blank F, von Garnier C, Stumbles PA, Strickland DH.

Physiol Rep. 2016 Nov;4(21). pii: e13021. Epub 2016 Nov 15.


Identification and Characterization of a Dendritic Cell Precursor in Parenchymal Lung Tissue.

von Garnier C, Blank F, Rothen-Rutishauser B, Goethert JR, Holt PG, Stumbles PA, Strickland DH.

Am J Respir Cell Mol Biol. 2017 Mar;56(3):353-361. doi: 10.1165/rcmb.2016-0058OC.


Persistent and compartmentalised disruption of dendritic cell subpopulations in the lung following influenza A virus infection.

Strickland DH, Fear V, Shenton S, Wikstrom ME, Zosky G, Larcombe AN, Holt PG, Berry C, von Garnier C, Stumbles PA.

PLoS One. 2014 Nov 14;9(11):e111520. doi: 10.1371/journal.pone.0111520. eCollection 2014.


Connective tissue growth factor is expressed in bone marrow stromal cells and promotes interleukin-7-dependent B lymphopoiesis.

Cheung LC, Strickland DH, Howlett M, Ford J, Charles AK, Lyons KM, Brigstock DR, Goldschmeding R, Cole CH, Alexander WS, Kees UR.

Haematologica. 2014 Jul;99(7):1149-56. doi: 10.3324/haematol.2013.102327. Epub 2014 Apr 11.


Defective respiratory tract immune surveillance in asthma: a primary causal factor in disease onset and progression.

Holt PG, Strickland DH, Hales BJ, Sly PD.

Chest. 2014 Feb;145(2):370-378. doi: 10.1378/chest.13-1341. Review.


Altered immunity and dendritic cell activity in the periphery of mice after long-term engraftment with bone marrow from ultraviolet-irradiated mice.

Ng RL, Scott NM, Strickland DH, Gorman S, Grimbaldeston MA, Norval M, Waithman J, Hart PH.

J Immunol. 2013 Jun 1;190(11):5471-84. doi: 10.4049/jimmunol.1202786. Epub 2013 May 1.


Size-dependent uptake of particles by pulmonary antigen-presenting cell populations and trafficking to regional lymph nodes.

Blank F, Stumbles PA, Seydoux E, Holt PG, Fink A, Rothen-Rutishauser B, Strickland DH, von Garnier C.

Am J Respir Cell Mol Biol. 2013 Jul;49(1):67-77. doi: 10.1165/rcmb.2012-0387OC.


Neonatal antigen-presenting cells are functionally more quiescent in children born under traditional compared with modern environmental conditions.

Lisciandro JG, Prescott SL, Nadal-Sims MG, Devitt CJ, Richmond PC, Pomat W, Siba PM, Holt PG, Strickland DH, van den Biggelaar AH.

J Allergy Clin Immunol. 2012 Nov;130(5):1167-1174.e10. doi: 10.1016/j.jaci.2012.06.005. Epub 2012 Jul 19.


Toward homeostasis: regulatory dendritic cells from the bone marrow of mice with inflammation of the airways and peritoneal cavity.

Scott NM, Ng RL, Strickland DH, Bisley JL, Bazely SA, Gorman S, Norval M, Hart PH.

Am J Pathol. 2012 Aug;181(2):535-47. doi: 10.1016/j.ajpath.2012.04.007. Epub 2012 Jun 5.


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