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Items: 1 to 20 of 57


The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research.

Das S; Extracellular RNA Communication Consortium, Ansel KM, Bitzer M, Breakefield XO, Charest A, Galas DJ, Gerstein MB, Gupta M, Milosavljevic A, McManus MT, Patel T, Raffai RL, Rozowsky J, Roth ME, Saugstad JA, Van Keuren-Jensen K, Weaver AM, Laurent LC.

Cell. 2019 Apr 4;177(2):231-242. doi: 10.1016/j.cell.2019.03.023. Review.


The Membrane-Active Phytopeptide Cycloviolacin O2 Simultaneously Targets HIV-1-infected Cells and Infectious Viral Particles to Potentiate the Efficacy of Antiretroviral Drugs.

Gerlach SL, Chandra PK, Roy U, Gunasekera S, Göransson U, Wimley WC, Braun SE, Mondal D.

Medicines (Basel). 2019 Feb 28;6(1). pii: E33. doi: 10.3390/medicines6010033.


Mesenchymal stem cells are attracted to latent HIV-1-infected cells and enable virus reactivation via a non-canonical PI3K-NFκB signaling pathway.

Chandra PK, Gerlach SL, Wu C, Khurana N, Swientoniewski LT, Abdel-Mageed AB, Li J, Braun SE, Mondal D.

Sci Rep. 2018 Oct 2;8(1):14702. doi: 10.1038/s41598-018-32657-y.


High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer.

Datta A, Kim H, McGee L, Johnson AE, Talwar S, Marugan J, Southall N, Hu X, Lal M, Mondal D, Ferrer M, Abdel-Mageed AB.

Sci Rep. 2018 May 25;8(1):8161. doi: 10.1038/s41598-018-26411-7.


PRL‑3 increases the aggressive phenotype of prostate cancer cells in vitro and its expression correlates with high-grade prostate tumors in patients.

Edwards DR, Moroz K, Zhang H, Mulholland D, Abdel-Mageed AB, Mondal D.

Int J Oncol. 2018 Feb;52(2):402-412. doi: 10.3892/ijo.2017.4208. Epub 2017 Nov 20.


The Antiretroviral Agent Nelfinavir Mesylate: A Potential Therapy for Systemic Sclerosis.

Sanchez CG, Molinski SV, Gongora R, Sosulski M, Fuselier T, MacKinnon SS, Mondal D, Lasky JA.

Arthritis Rheumatol. 2018 Jan;70(1):115-126. doi: 10.1002/art.40326. Epub 2017 Dec 8.


Multimodal actions of the phytochemical sulforaphane suppress both AR and AR-V7 in 22Rv1 cells: Advocating a potent pharmaceutical combination against castration-resistant prostate cancer.

Khurana N, Kim H, Chandra PK, Talwar S, Sharma P, Abdel-Mageed AB, Sikka SC, Mondal D.

Oncol Rep. 2017 Nov;38(5):2774-2786. doi: 10.3892/or.2017.5932. Epub 2017 Aug 30.


Manumycin A suppresses exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration-resistant prostate cancer cells.

Datta A, Kim H, Lal M, McGee L, Johnson A, Moustafa AA, Jones JC, Mondal D, Ferrer M, Abdel-Mageed AB.

Cancer Lett. 2017 Nov 1;408:73-81. doi: 10.1016/j.canlet.2017.08.020. Epub 2017 Aug 24.


An Ex Vivo Tissue Culture Model for Anti-angiogenic Drug Testing.

Azimi MS, Lacey M, Mondal D, Murfee WL.

Methods Mol Biol. 2016;1464:85-95.


Estradiol-ERβ2 signaling axis confers growth and migration of CRPC cells through TMPRSS2-ETV5 gene fusion.

Kim H, Datta A, Talwar S, Saleem SN, Mondal D, Abdel-Mageed AB.

Oncotarget. 2016 Aug 17;8(38):62820-62833. doi: 10.18632/oncotarget.11355. eCollection 2017 Sep 8.


Sulforaphane increases the efficacy of anti-androgens by rapidly decreasing androgen receptor levels in prostate cancer cells.

Khurana N, Talwar S, Chandra PK, Sharma P, Abdel-Mageed AB, Mondal D, Sikka SC.

Int J Oncol. 2016 Oct;49(4):1609-19. doi: 10.3892/ijo.2016.3641. Epub 2016 Aug 2.


Tripping on TRIB3 at the junction of health, metabolic dysfunction and cancer.

Mondal D, Mathur A, Chandra PK.

Biochimie. 2016 May;124:34-52. doi: 10.1016/j.biochi.2016.02.005. Epub 2016 Feb 6. Review.


Nelfinavir targets multiple drug resistance mechanisms to increase the efficacy of doxorubicin in MCF-7/Dox breast cancer cells.

Chakravarty G, Mathur A, Mallade P, Gerlach S, Willis J, Datta A, Srivastav S, Abdel-Mageed AB, Mondal D.

Biochimie. 2016 May;124:53-64. doi: 10.1016/j.biochi.2016.01.014. Epub 2016 Feb 1.


Role of MRP transporters in regulating antimicrobial drug inefficacy and oxidative stress-induced pathogenesis during HIV-1 and TB infections.

Roy U, Barber P, Tse-Dinh YC, Batrakova EV, Mondal D, Nair M.

Front Microbiol. 2015 Sep 17;6:948. doi: 10.3389/fmicb.2015.00948. eCollection 2015. Review.


Meeting report: discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium.

Laurent LC, Abdel-Mageed AB, Adelson PD, Arango J, Balaj L, Breakefield X, Carlson E, Carter BS, Majem B, Chen CC, Cocucci E, Danielson K, Courtright A, Das S, Abd Elmageed ZY, Enderle D, Ezrin A, Ferrer M, Freedman J, Galas D, Gandhi R, Huentelman MJ, Van Keuren-Jensen K, Kalani Y, Kim Y, Krichevsky AM, Lai C, Lal-Nag M, Laurent CD, Leonardo T, Li F, Malenica I, Mondal D, Nejad P, Patel T, Raffai RL, Rubio R, Skog J, Spetzler R, Sun J, Tanriverdi K, Vickers K, Wang L, Wang Y, Wei Z, Weiner HL, Wong D, Yan IK, Yeri A, Gould S.

J Extracell Vesicles. 2015 Aug 28;4:26533. doi: 10.3402/jev.v4.26533. eCollection 2015.


Doxorubicin resistance in breast cancer is driven by light at night-induced disruption of the circadian melatonin signal.

Xiang S, Dauchy RT, Hauch A, Mao L, Yuan L, Wren MA, Belancio VP, Mondal D, Frasch T, Blask DE, Hill SM.

J Pineal Res. 2015 Aug;59(1):60-9. doi: 10.1111/jpi.12239. Epub 2015 Apr 20.


Selective targeting of FAK-Pyk2 axis by alpha-naphthoflavone abrogates doxorubicin resistance in breast cancer cells.

Datta A, Bhasin N, Kim H, Ranjan M, Rider B, Abd Elmageed ZY, Mondal D, Agrawal KC, Abdel-Mageed AB.

Cancer Lett. 2015 Jun 28;362(1):25-35. doi: 10.1016/j.canlet.2015.03.009. Epub 2015 Mar 18.


An ex vivo model for anti-angiogenic drug testing on intact microvascular networks.

Azimi MS, Myers L, Lacey M, Stewart SA, Shi Q, Katakam PV, Mondal D, Murfee WL.

PLoS One. 2015 Mar 5;10(3):e0119227. doi: 10.1371/journal.pone.0119227. eCollection 2015.


Subverting ER-stress towards apoptosis by nelfinavir and curcumin coexposure augments docetaxel efficacy in castration resistant prostate cancer cells.

Mathur A, Abd Elmageed ZY, Liu X, Kostochka ML, Zhang H, Abdel-Mageed AB, Mondal D.

PLoS One. 2014 Aug 14;9(8):e103109. doi: 10.1371/journal.pone.0103109. eCollection 2014.


In vivo anticancer synergy mechanism of doxorubicin and verapamil combination treatment is impaired in BALB/c mice with metastatic breast cancer.

McCarthy M, Auda G, Agrawal S, Taylor A, Backstrom Z, Mondal D, Moroz K, Dash S.

Exp Mol Pathol. 2014 Aug;97(1):6-15. doi: 10.1016/j.yexmp.2014.04.013. Epub 2014 Apr 26.


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