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Items: 1 to 20 of 58


CRISPR/Cas9-mediated knockin of human factor IX into swine factor IX locus effectively alleviates bleeding in hemophilia B pigs.

Chen J, An B, Yu B, Peng X, Yuan H, Yang Q, Chen X, Yu T, Wang L, Zhang X, Wang H, Zou X, Pang D, Ouyang H, Tang X.

Haematologica. 2020 Jan 23. pii: haematol.2019.224063. doi: 10.3324/haematol.2019.224063. [Epub ahead of print]


Generation of pRSAD2 gene knock-in pig via CRISPR/Cas9 technology.

Xie Z, Jiao H, Xiao H, Jiang Y, Liu Z, Qi C, Zhao D, Jiao S, Yu T, Tang X, Pang D, Ouyang H.

Antiviral Res. 2019 Dec 17;174:104696. doi: 10.1016/j.antiviral.2019.104696. [Epub ahead of print]


Preparation of a new type 2 diabetic miniature pig model via the CRISPR/Cas9 system.

Zou X, Ouyang H, Yu T, Chen X, Pang D, Tang X, Chen C.

Cell Death Dis. 2019 Oct 28;10(11):823. doi: 10.1038/s41419-019-2056-5.


Efficient base editing by RNA-guided cytidine base editors (CBEs) in pigs.

Yuan H, Yu T, Wang L, Yang L, Zhang Y, Liu H, Li M, Tang X, Liu Z, Li Z, Lu C, Chen X, Pang D, Ouyang H.

Cell Mol Life Sci. 2019 Jul 13. doi: 10.1007/s00018-019-03205-2. [Epub ahead of print]


Porcine HMGCR Inhibits Porcine Circovirus Type 2 Infection by Directly Interacting with the Viral Proteins.

Ouyang T, Niu G, Zhang Y, Liu X, Zhang X, Zhang S, Geng Y, Pang D, Ouyang H, Ren L.

Viruses. 2019 Jun 11;11(6). pii: E544. doi: 10.3390/v11060544.


Biomimetic Octopus-like Particles for Ultraspecific Capture and Detection of Pathogens.

Lv D, Jiao H, Dong J, Sheng L, Liu J, Dong H, Su A, Zhang M, Xia Z, Oswald JT, Pang D, Liu J, Ouyang H.

ACS Appl Mater Interfaces. 2019 Jun 26;11(25):22164-22170. doi: 10.1021/acsami.9b05666. Epub 2019 Jun 12.


Abnormality of hepatic triglyceride metabolism in ApcMin/+ mice with colon cancer cachexia.

Yu B, Zhang M, Chen J, Wang L, Peng X, Zhang X, Wang H, Wang A, Zhao D, Pang D, OuYang H, Tang X.

Life Sci. 2019 Jun 15;227:201-211. doi: 10.1016/j.lfs.2019.04.041. Epub 2019 Apr 17.


Magnetic Multiarm Scaffold for the One-Step Purification of Epitope-Specific Neutralizing Antibodies.

Lv D, Dong H, Su A, Qin Y, Dong J, Ma L, Li J, Jiao H, Zhang M, Pang D, Liu J, Ouyang H.

Anal Chem. 2019 May 7;91(9):6172-6179. doi: 10.1021/acs.analchem.9b00769. Epub 2019 Apr 26.


Human cells are permissive for the productive infection of porcine circovirus type 2 in vitro.

Liu X, Ouyang T, Ouyang H, Liu X, Niu G, Huo W, Yin W, Pang D, Ren L.

Sci Rep. 2019 Apr 4;9(1):5638. doi: 10.1038/s41598-019-42210-0.


Data Mining and Validation of AMPK Pathway as a Novel Candidate Role Affecting Intramuscular Fat Content in Pigs.

Yao C, Pang D, Lu C, Xu A, Huang P, Ouyang H, Yu H.

Animals (Basel). 2019 Apr 1;9(4). pii: E137. doi: 10.3390/ani9040137.


Development of Whole-Porcine Monoclonal Antibodies with Potent Neutralization Activity against Classical Swine Fever Virus from Single B Cells.

Dong H, Su A, Lv D, Ma L, Dong J, Guo N, Ren L, Jiao H, Pang D, Ouyan H.

ACS Synth Biol. 2019 May 17;8(5):989-1000. doi: 10.1021/acssynbio.8b00365. Epub 2019 Apr 12.


Cyclodextrin Ameliorates the Progression of Atherosclerosis via Increasing High-Density Lipoprotein Cholesterol Plasma Levels and Anti-inflammatory Effects in Rabbits.

Wang H, Zhang X, Yu B, Peng X, Liu Y, Wang A, Zhao D, Pang D, OuYang H, Tang X.

J Cardiovasc Pharmacol. 2019 May;73(5):334-342. doi: 10.1097/FJC.0000000000000660.


The Possible Role of Complete Loss of Myostatin in Limiting Excessive Proliferation of Muscle Cells (C2C12) via Activation of MicroRNAs.

Huang P, Pang D, Wang K, Xu A, Yao C, Li M, You W, Wang Q, Yu H.

Int J Mol Sci. 2019 Feb 2;20(3). pii: E643. doi: 10.3390/ijms20030643.


CRISPR/Cas9-Mediated Hitchhike Expression of Functional shRNAs at the Porcine miR-17-92 Cluster.

Lu C, Pang D, Li M, Yuan H, Yu T, Huang P, Li J, Chen X, Jiao H, Xie Z, Ouyang H.

Cells. 2019 Feb 1;8(2). pii: E113. doi: 10.3390/cells8020113.


Genetically modified pigs are protected from classical swine fever virus.

Xie Z, Pang D, Yuan H, Jiao H, Lu C, Wang K, Yang Q, Li M, Chen X, Yu T, Chen X, Dai Z, Peng Y, Tang X, Li Z, Wang T, Guo H, Li L, Tu C, Lai L, Ouyang H.

PLoS Pathog. 2018 Dec 13;14(12):e1007193. doi: 10.1371/journal.ppat.1007193. eCollection 2018 Dec.


miR-23b promotes cutaneous wound healing through inhibition of the inflammatory responses by targeting ASK1.

Li H, Han X, Zuo K, Li L, Liu J, Yuan X, Shen Y, Shao M, Pang D, Chu Y, Zhao B.

Acta Biochim Biophys Sin (Shanghai). 2018 Nov 1;50(11):1104-1113. doi: 10.1093/abbs/gmy109.


Immunogenicity evaluation of inactivated virus and purified proteins of porcine circovirus type 2 in mice.

Liu X, Ouyang T, Ma T, Ouyang H, Pang D, Ren L.

BMC Vet Res. 2018 Apr 23;14(1):137. doi: 10.1186/s12917-018-1461-9.


Truncated C-terminus of fibrillin-1 induces Marfanoid-progeroid-lipodystrophy (MPL) syndrome in rabbit.

Chen M, Yao B, Yang Q, Deng J, Song Y, Sui T, Zhou L, Yao H, Xu Y, Ouyang H, Pang D, Li Z, Lai L.

Dis Model Mech. 2018 Apr 9;11(4). pii: dmm031542. doi: 10.1242/dmm.031542.


Site-Specific Fat-1 Knock-In Enables Significant Decrease of n-6PUFAs/n-3PUFAs Ratio in Pigs.

Li M, Ouyang H, Yuan H, Li J, Xie Z, Wang K, Yu T, Liu M, Chen X, Tang X, Jiao H, Pang D.

G3 (Bethesda). 2018 May 4;8(5):1747-1754. doi: 10.1534/g3.118.200114.


Alteration in microRNA-25 expression regulate cardiac function via renin secretion.

Li H, Xie Y, Liu Y, Qi Y, Tang C, Li X, Zuo K, Sun D, Shen Y, Pang D, Chu Y, Zhao B.

Exp Cell Res. 2018 Apr 1;365(1):119-128. doi: 10.1016/j.yexcr.2018.02.029. Epub 2018 Feb 28.


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