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Items: 1 to 20 of 34

1.

The landscape of myeloid and astrocyte phenotypes in acute multiple sclerosis lesions.

Park C, Ponath G, Levine-Ritterman M, Bull E, Swanson EC, De Jager PL, Segal BM, Pitt D.

Acta Neuropathol Commun. 2019 Aug 12;7(1):130. doi: 10.1186/s40478-019-0779-2.

2.

Multiplexed imaging of immune cells in staged multiple sclerosis lesions by mass cytometry.

Ramaglia V, Sheikh-Mohamed S, Legg K, Park C, Rojas OL, Zandee S, Fu F, Ornatsky O, Swanson EC, Pitt D, Prat A, McKee TD, Gommerman JL.

Elife. 2019 Aug 1;8. pii: e48051. doi: 10.7554/eLife.48051.

3.

Quantitative susceptibility mapping identifies inflammation in a subset of chronic multiple sclerosis lesions.

Kaunzner UW, Kang Y, Zhang S, Morris E, Yao Y, Pandya S, Hurtado Rua SM, Park C, Gillen KM, Nguyen TD, Wang Y, Pitt D, Gauthier SA.

Brain. 2019 Jan 1;142(1):133-145. doi: 10.1093/brain/awy296.

PMID:
30561514
4.

Enhanced astrocyte responses are driven by a genetic risk allele associated with multiple sclerosis.

Ponath G, Lincoln MR, Levine-Ritterman M, Park C, Dahlawi S, Mubarak M, Sumida T, Airas L, Zhang S, Isitan C, Nguyen TD, Raine CS, Hafler DA, Pitt D.

Nat Commun. 2018 Dec 17;9(1):5337. doi: 10.1038/s41467-018-07785-8.

5.

Astrocytes play a crucial role in the formation and evolution of MS lesions - Yes.

Pitt D, Ponath G.

Mult Scler. 2019 Jan;25(1):15-17. doi: 10.1177/1352458518793026. Epub 2018 Aug 23. No abstract available.

PMID:
30136895
6.

Magnetic susceptibility increases as diamagnetic molecules breakdown: Myelin digestion during multiple sclerosis lesion formation contributes to increase on QSM.

Deh K, Ponath GD, Molvi Z, Parel GT, Gillen KM, Zhang S, Nguyen TD, Spincemaille P, Ma Y, Gupta A, Gauthier SA, Pitt D, Wang Y.

J Magn Reson Imaging. 2018 Nov;48(5):1281-1287. doi: 10.1002/jmri.25997. Epub 2018 Mar 8.

PMID:
29517817
7.

Significance and In Vivo Detection of Iron-Laden Microglia in White Matter Multiple Sclerosis Lesions.

Gillen KM, Mubarak M, Nguyen TD, Pitt D.

Front Immunol. 2018 Feb 19;9:255. doi: 10.3389/fimmu.2018.00255. eCollection 2018. Review.

8.

The Role of Astrocytes in Multiple Sclerosis.

Ponath G, Park C, Pitt D.

Front Immunol. 2018 Feb 19;9:217. doi: 10.3389/fimmu.2018.00217. eCollection 2018. Review.

9.

Myeloid cell plasticity in the evolution of central nervous system autoimmunity.

Giles DA, Washnock-Schmid JM, Duncker PC, Dahlawi S, Ponath G, Pitt D, Segal BM.

Ann Neurol. 2018 Jan;83(1):131-141. doi: 10.1002/ana.25128. Epub 2018 Jan 14.

10.

Podoplanin is a negative regulator of Th17 inflammation.

Nylander AN, Ponath GD, Axisa PP, Mubarak M, Tomayko M, Kuchroo VK, Pitt D, Hafler DA.

JCI Insight. 2017 Sep 7;2(17). pii: 92321. doi: 10.1172/jci.insight.92321. eCollection 2017 Sep 7.

11.

Clinical quantitative susceptibility mapping (QSM): Biometal imaging and its emerging roles in patient care.

Wang Y, Spincemaille P, Liu Z, Dimov A, Deh K, Li J, Zhang Y, Yao Y, Gillen KM, Wilman AH, Gupta A, Tsiouris AJ, Kovanlikaya I, Chiang GC, Weinsaft JW, Tanenbaum L, Chen W, Zhu W, Chang S, Lou M, Kopell BH, Kaplitt MG, Devos D, Hirai T, Huang X, Korogi Y, Shtilbans A, Jahng GH, Pelletier D, Gauthier SA, Pitt D, Bush AI, Brittenham GM, Prince MR.

J Magn Reson Imaging. 2017 Oct;46(4):951-971. doi: 10.1002/jmri.25693. Epub 2017 Mar 10. Review.

12.

Myelin phagocytosis by astrocytes after myelin damage promotes lesion pathology.

Ponath G, Ramanan S, Mubarak M, Housley W, Lee S, Sahinkaya FR, Vortmeyer A, Raine CS, Pitt D.

Brain. 2017 Feb;140(2):399-413. doi: 10.1093/brain/aww298. Epub 2016 Dec 21.

13.

CNS demyelination and enhanced myelin-reactive responses after ipilimumab treatment.

Cao Y, Nylander A, Ramanan S, Goods BA, Ponath G, Zabad R, Chiang VL, Vortmeyer AO, Hafler DA, Pitt D.

Neurology. 2016 Apr 19;86(16):1553-6. doi: 10.1212/WNL.0000000000002594. Epub 2016 Mar 16. No abstract available.

14.

Analysis of miRNA in Normal Appearing White Matter to Identify Altered CNS Pathways in Multiple Sclerosis.

Guerau-de-Arellano M, Liu Y, Meisen WH, Pitt D, Racke MK, Lovett-Racke AE.

J Autoimmune Disord. 2015;1(1). pii: 6.

15.

Iron in Multiple Sclerosis and Its Noninvasive Imaging with Quantitative Susceptibility Mapping.

Stüber C, Pitt D, Wang Y.

Int J Mol Sci. 2016 Jan 14;17(1). pii: E100. doi: 10.3390/ijms17010100. Review.

16.

Biomarkers in multiple sclerosis.

Housley WJ, Pitt D, Hafler DA.

Clin Immunol. 2015 Nov;161(1):51-8. doi: 10.1016/j.clim.2015.06.015. Epub 2015 Jul 2. Review.

PMID:
26143623
17.

Concise review: modeling multiple sclerosis with stem cell biological platforms: toward functional validation of cellular and molecular phenotypes in inflammation-induced neurodegeneration.

Orack JC, Deleidi M, Pitt D, Mahajan K, Nicholas JA, Boster AL, Racke MK, Comabella M, Watanabe F, Imitola J.

Stem Cells Transl Med. 2015 Mar;4(3):252-60. doi: 10.5966/sctm.2014-0133. Epub 2015 Jan 15. Review.

18.

Quantitative susceptibility mapping (QSM) of white matter multiple sclerosis lesions: Interpreting positive susceptibility and the presence of iron.

Wisnieff C, Ramanan S, Olesik J, Gauthier S, Wang Y, Pitt D.

Magn Reson Med. 2015 Aug;74(2):564-70. doi: 10.1002/mrm.25420. Epub 2014 Aug 18.

19.

B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes.

Stern JN, Yaari G, Vander Heiden JA, Church G, Donahue WF, Hintzen RQ, Huttner AJ, Laman JD, Nagra RM, Nylander A, Pitt D, Ramanan S, Siddiqui BA, Vigneault F, Kleinstein SH, Hafler DA, O'Connor KC.

Sci Transl Med. 2014 Aug 6;6(248):248ra107. doi: 10.1126/scitranslmed.3008879.

20.

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