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Items: 1 to 20 of 54

1.

Erratum: Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes.

Mariño E, Richards JL, McLeod KH, Stanley D, Yap YA, Knight J, McKenzie C, Kranich J, Oliveira AC, Rossello FJ, Krishnamurthy B, Nefzger CM, Macia L, Thorburn A, Baxter AG, Morahan G, Wong LH, Polo JM, Moore RJ, Lockett TJ, Clarke JM, Topping DL, Harrison LC, Mackay CR.

Nat Immunol. 2017 Oct 18;18(11):1271. doi: 10.1038/ni1117-1271c.

PMID:
29044240
2.

Dietary Propolis Ameliorates Dextran Sulfate Sodium-Induced Colitis and Modulates the Gut Microbiota in Rats Fed a Western Diet.

Wang K, Jin X, You M, Tian W, Le Leu RK, Topping DL, Conlon MA, Wu L, Hu F.

Nutrients. 2017 Aug 14;9(8). pii: E875. doi: 10.3390/nu9080875.

3.

Erratum: Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes.

Mariño E, Richards JL, McLeod KH, Stanley D, Yap YA, Knight J, McKenzie C, Kranich J, Oliveira AC, Rossello FJ, Krishnamurthy B, Nefzger CM, Macia L, Thorburn A, Baxter AG, Morahan G, Wong LH, Polo JM, Moore RJ, Lockett TJ, Clarke JM, Topping DL, Harrison LC, Mackay CR.

Nat Immunol. 2017 Jul 19;18(8):951. doi: 10.1038/ni0817-951c. No abstract available.

PMID:
28722715
4.

Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes.

Mariño E, Richards JL, McLeod KH, Stanley D, Yap YA, Knight J, McKenzie C, Kranich J, Oliveira AC, Rossello FJ, Krishnamurthy B, Nefzger CM, Macia L, Thorburn A, Baxter AG, Morahan G, Wong LH, Polo JM, Moore RJ, Lockett TJ, Clarke JM, Topping DL, Harrison LC, Mackay CR.

Nat Immunol. 2017 May;18(5):552-562. doi: 10.1038/ni.3713. Epub 2017 Mar 27. Erratum in: Nat Immunol. 2017 Jul 19;18(8):951. Erratum in: Nat Immunol. 2017 Oct 18;18(11):1271.

PMID:
28346408
5.

Targeted delivery of short-chain fatty acids to the human large bowel.

Topping DL.

Am J Clin Nutr. 2016 Jul;104(1):1-2. doi: 10.3945/ajcn.116.137711. Epub 2016 Jun 22. No abstract available.

PMID:
27334235
6.

High wholegrain barley β-glucan lowers food intake but does not alter small intestinal macronutrient digestibility in ileorectostomised rats.

Belobrajdic DP, Hino S, Kondo T, Jobling SA, Morell MK, Topping DL, Morita T, Bird AR.

Int J Food Sci Nutr. 2016 Sep;67(6):678-85. doi: 10.1080/09637486.2016.1194811. Epub 2016 Jun 9.

PMID:
27282074
7.

Polyphenol-Rich Propolis Extracts Strengthen Intestinal Barrier Function by Activating AMPK and ERK Signaling.

Wang K, Jin X, Chen Y, Song Z, Jiang X, Hu F, Conlon MA, Topping DL.

Nutrients. 2016 May 7;8(5). pii: E272. doi: 10.3390/nu8050272.

8.

Dietary polysaccharides and polyphenols can promote health by influencing gut microbiota populations.

Conlon MA, Topping DL.

Food Funct. 2016 Apr;7(4):1730. doi: 10.1039/c6fo90009g. No abstract available.

PMID:
27068450
9.

Soluble arabinoxylan alters digesta flow and protein digestion of red meat-containing diets in pigs.

Zhang D, Williams BA, Mikkelsen D, Li X, Keates HL, Lisle AT, Collins HM, Fincher GB, Bird AR, Topping DL, Gidley MJ, Bryden WL.

Nutrition. 2015 Sep;31(9):1141-7. doi: 10.1016/j.nut.2015.03.006. Epub 2015 Apr 7.

PMID:
26233873
10.

Butyrylated starch intake can prevent red meat-induced O6-methyl-2-deoxyguanosine adducts in human rectal tissue: a randomised clinical trial.

Le Leu RK, Winter JM, Christophersen CT, Young GP, Humphreys KJ, Hu Y, Gratz SW, Miller RB, Topping DL, Bird AR, Conlon MA.

Br J Nutr. 2015 Jul;114(2):220-30. doi: 10.1017/S0007114515001750. Epub 2015 Jun 17.

11.

Lowering of large bowel butyrate levels in healthy populations is unlikely to be beneficial.

Conlon MA, Bird AR, Clarke JM, Le Leu RK, Christophersen CT, Lockett TJ, Topping DL.

J Nutr. 2015 May;145(5):1030-1. doi: 10.3945/jn.114.209460. No abstract available.

PMID:
25934666
12.

Resistant starch alters colonic contractility and expression of related genes in rats fed a Western diet.

Patten GS, Kerr CA, Dunne RA, Shaw JM, Bird AR, Regina A, Morell MK, Lockett TJ, Molloy PL, Abeywardena MY, Topping DL, Conlon MA.

Dig Dis Sci. 2015 Jun;60(6):1624-32. doi: 10.1007/s10620-015-3537-8. Epub 2015 Jan 24.

PMID:
25616610
13.

Butyrylated starch affects colorectal cancer markers beneficially and dose-dependently in genotoxin-treated rats.

Toden S, Lockett TJ, Topping DL, Scherer BL, Watson EJ, Southwood JG, Clarke JM.

Cancer Biol Ther. 2014;15(11):1515-23. doi: 10.4161/15384047.2014.955764.

14.

Dietary manipulation of oncogenic microRNA expression in human rectal mucosa: a randomized trial.

Humphreys KJ, Conlon MA, Young GP, Topping DL, Hu Y, Winter JM, Bird AR, Cobiac L, Kennedy NA, Michael MZ, Le Leu RK.

Cancer Prev Res (Phila). 2014 Aug;7(8):786-95. doi: 10.1158/1940-6207.CAPR-14-0053.

15.

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells.

Furusawa Y, Obata Y, Fukuda S, Endo TA, Nakato G, Takahashi D, Nakanishi Y, Uetake C, Kato K, Kato T, Takahashi M, Fukuda NN, Murakami S, Miyauchi E, Hino S, Atarashi K, Onawa S, Fujimura Y, Lockett T, Clarke JM, Topping DL, Tomita M, Hori S, Ohara O, Morita T, Koseki H, Kikuchi J, Honda K, Hase K, Ohno H.

Nature. 2013 Dec 19;504(7480):446-50. doi: 10.1038/nature12721. Epub 2013 Nov 13. Erratum in: Nature. 2014 Feb 13;506(7487):254.

PMID:
24226770
16.

Butyrylated starch increases colonic butyrate concentration but has limited effects on immunity in healthy physically active individuals.

West NP, Christophersen CT, Pyne DB, Cripps AW, Conlon MA, Topping DL, Kang S, McSweeney CS, Fricker PA, Aguirre D, Clarke JM.

Exerc Immunol Rev. 2013;19:102-19.

17.

Colorectal carcinogenesis: a cellular response to sustained risk environment.

Fung KY, Ooi CC, Zucker MH, Lockett T, Williams DB, Cosgrove LJ, Topping DL.

Int J Mol Sci. 2013 Jun 27;14(7):13525-41. doi: 10.3390/ijms140713525. Review.

18.

A review of the potential mechanisms for the lowering of colorectal oncogenesis by butyrate.

Fung KY, Cosgrove L, Lockett T, Head R, Topping DL.

Br J Nutr. 2012 Sep;108(5):820-31. doi: 10.1017/S0007114512001948. Epub 2012 Jun 7. Review.

PMID:
22676885
19.

Resistant starches protect against colonic DNA damage and alter microbiota and gene expression in rats fed a Western diet.

Conlon MA, Kerr CA, McSweeney CS, Dunne RA, Shaw JM, Kang S, Bird AR, Morell MK, Lockett TJ, Molloy PL, Regina A, Toden S, Clarke JM, Topping DL.

J Nutr. 2012 May;142(5):832-40. doi: 10.3945/jn.111.147660. Epub 2012 Mar 28.

20.

An arabinoxylan-rich fraction from wheat enhances caecal fermentation and protects colonocyte DNA against diet-induced damage in pigs.

Belobrajdic DP, Bird AR, Conlon MA, Williams BA, Kang S, McSweeney CS, Zhang D, Bryden WL, Gidley MJ, Topping DL.

Br J Nutr. 2012 May;107(9):1274-82. doi: 10.1017/S0007114511004338. Epub 2011 Nov 24.

PMID:
22115395

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