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Items: 1 to 20 of 34

1.

The Effect of Silymarin Flavonolignans and Their Sulfated Conjugates on Platelet Aggregation and Blood Vessels Ex Vivo.

Pourová J, Applová L, Macáková K, Vopršalová M, Migkos T, Bentanachs R, Biedermann D, Petrásková L, Tvrdý V, Hrubša M, Karlíčková J, Křen V, Valentová K, Mladěnka P.

Nutrients. 2019 Sep 24;11(10). pii: E2286. doi: 10.3390/nu11102286.

2.

Antioxidant, Anti-Inflammatory, and Multidrug Resistance Modulation Activity of Silychristin Derivatives.

Viktorová J, Dobiasová S, Řehořová K, Biedermann D, Káňová K, Šeborová K, Václavíková R, Valentová K, Ruml T, Křen V, Macek T.

Antioxidants (Basel). 2019 Aug 14;8(8). pii: E303. doi: 10.3390/antiox8080303.

3.

Preparation of Retinoyl-Flavonolignan Hybrids and Their Antioxidant Properties.

Chambers CS, Biedermann D, Valentová K, Petrásková L, Viktorová J, Kuzma M, Křen V.

Antioxidants (Basel). 2019 Jul 23;8(7). pii: E236. doi: 10.3390/antiox8070236.

4.

Chemoenzymatic Synthesis and Radical Scavenging of Sulfated Hydroxytyrosol, Tyrosol, and Acetylated Derivatives.

Begines P, Biedermann D, Valentová K, Petrásková L, Pelantová H, Maya I, Fernández-Bolaños JG, Křen V.

J Agric Food Chem. 2019 Jul 3;67(26):7281-7288. doi: 10.1021/acs.jafc.9b01065. Epub 2019 Jun 25.

PMID:
31198027
5.

A pilot study of the UVA-photoprotective potential of dehydrosilybin, isosilybin, silychristin, and silydianin on human dermal fibroblasts.

Rajnochová Svobodová A, Gabrielová E, Ulrichová J, Zálešák B, Biedermann D, Vostálová J.

Arch Dermatol Res. 2019 Aug;311(6):477-490. doi: 10.1007/s00403-019-01928-7. Epub 2019 May 11.

PMID:
31079190
6.

Defying Multidrug Resistance! Modulation of Related Transporters by Flavonoids and Flavonolignans.

Chambers CS, Viktorová J, Řehořová K, Biedermann D, Turková L, Macek T, Křen V, Valentová K.

J Agric Food Chem. 2019 Apr 3. doi: 10.1021/acs.jafc.9b00694. [Epub ahead of print]

PMID:
30907588
7.

Isolated Silymarin Flavonoids Increase Systemic and Hepatic Bilirubin Concentrations and Lower Lipoperoxidation in Mice.

Šuk J, Jašprová J, Biedermann D, Petrásková L, Valentová K, Křen V, Muchová L, Vítek L.

Oxid Med Cell Longev. 2019 Feb 12;2019:6026902. doi: 10.1155/2019/6026902. eCollection 2019.

8.

Skin Protective Activity of Silymarin and its Flavonolignans.

Vostálová J, Tinková E, Biedermann D, Kosina P, Ulrichová J, Rajnochová Svobodová A.

Molecules. 2019 Mar 14;24(6). pii: E1022. doi: 10.3390/molecules24061022.

9.

Modulation of Skin Inflammatory Response by Active Components of Silymarin.

Juráňová J, Aury-Landas J, Boumediene K, Baugé C, Biedermann D, Ulrichová J, Franková J.

Molecules. 2018 Dec 30;24(1). pii: E123. doi: 10.3390/molecules24010123.

10.

Dermal Delivery of Selected Polyphenols from Silybum marianum. Theoretical and Experimental Study.

Kosina P, Paloncýová M, Svobodová AR, Zálešák B, Biedermann D, Ulrichová J, Vostálová J.

Molecules. 2018 Dec 24;24(1). pii: E61. doi: 10.3390/molecules24010061.

11.

Differential Effects of the Flavonolignans Silybin, Silychristin and 2,3-Dehydrosilybin on Mesocestoides vogae Larvae (Cestoda) under Hypoxic and Aerobic In Vitro Conditions.

Hrčková G, Kubašková TM, Benada O, Kofroňová O, Tumová L, Biedermann D.

Molecules. 2018 Nov 16;23(11). pii: E2999. doi: 10.3390/molecules23112999.

12.

Interaction of isolated silymarin flavonolignans with iron and copper.

Tvrdý V, Catapano MC, Rawlik T, Karlíčková J, Biedermann D, Křen V, Mladěnka P, Valentová K.

J Inorg Biochem. 2018 Dec;189:115-123. doi: 10.1016/j.jinorgbio.2018.09.006. Epub 2018 Sep 13.

PMID:
30245273
13.

Sulfated Metabolites of Flavonolignans and 2,3-Dehydroflavonolignans: Preparation and Properties.

Valentová K, Purchartová K, Rydlová L, Roubalová L, Biedermann D, Petrásková L, Křenková A, Pelantová H, Holečková-Moravcová V, Tesařová E, Cvačka J, Vrba J, Ulrichová J, Křen V.

Int J Mol Sci. 2018 Aug 9;19(8). pii: E2349. doi: 10.3390/ijms19082349.

14.

In-Vitro Activity of Silybin and Related Flavonolignans against Leishmania infantum and L. donovani.

Olías-Molero AI, Jiménez-Antón MD, Biedermann D, Corral MJ, Alunda JM.

Molecules. 2018 Jun 27;23(7). pii: E1560. doi: 10.3390/molecules23071560.

15.

Molecular Defects in Cardiac Myofilament Ca2+-Regulation Due to Cardiomyopathy-Linked Mutations Can Be Reversed by Small Molecules Binding to Troponin.

Sheehan A, Messer AE, Papadaki M, Choudhry A, Kren V, Biedermann D, Blagg B, Khandelwal A, Marston SB.

Front Physiol. 2018 Mar 27;9:243. doi: 10.3389/fphys.2018.00243. eCollection 2018.

16.

Metabolism of flavonolignans in human hepatocytes.

Vrba J, Papoušková B, Roubalová L, Zatloukalová M, Biedermann D, Křen V, Valentová K, Ulrichová J, Vacek J.

J Pharm Biomed Anal. 2018 Apr 15;152:94-101. doi: 10.1016/j.jpba.2018.01.048. Epub 2018 Jan 31.

PMID:
29414024
17.

The silymarin composition… and why does it matter???

Chambers CS, Holečková V, Petrásková L, Biedermann D, Valentová K, Buchta M, Křen V.

Food Res Int. 2017 Oct;100(Pt 3):339-353. doi: 10.1016/j.foodres.2017.07.017. Epub 2017 Jul 12. Review.

PMID:
28964357
18.

Quercetin and its analogues: optical and acido-basic properties.

Biler M, Biedermann D, Valentová K, Křen V, Kubala M.

Phys Chem Chem Phys. 2017 Oct 11;19(39):26870-26879. doi: 10.1039/c7cp03845c.

PMID:
28952614
19.

Oxidation of Natural Bioactive Flavonolignan 2,3-Dehydrosilybin: An Electrochemical and Spectral Study.

Sokolová R, Kocábová J, Marhol P, Fiedler J, Biedermann D, Vacek J, Křen V.

J Phys Chem B. 2017 Jul 20;121(28):6841-6846. doi: 10.1021/acs.jpcb.7b04651. Epub 2017 Jul 11.

PMID:
28654289
20.

Flavonolignan 2,3-dehydrosilydianin activates Nrf2 and upregulates NAD(P)H:quinone oxidoreductase 1 in Hepa1c1c7 cells.

Roubalová L, Dinkova-Kostova AT, Biedermann D, Křen V, Ulrichová J, Vrba J.

Fitoterapia. 2017 Jun;119:115-120. doi: 10.1016/j.fitote.2017.04.012. Epub 2017 Apr 24.

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