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Items: 1 to 20 of 92

1.

An Enteric-Coated Polyelectrolyte Nanocomplex Delivers Insulin in Rat Intestinal Instillations when Combined with a Permeation Enhancer.

Sladek S, McCartney F, Eskander M, Dunne DJ, Santos-Martinez MJ, Benetti F, Tajber L, Brayden DJ.

Pharmaceutics. 2020 Mar 12;12(3). pii: E259. doi: 10.3390/pharmaceutics12030259.

2.

Silica-Coated Nanoparticles with a Core of Zinc, l-Arginine, and a Peptide Designed for Oral Delivery.

Hristov D, McCartney F, Beirne J, Mahon E, Reid S, Bhattacharjee S, Penarier G, Werner U, Bazile D, Brayden DJ.

ACS Appl Mater Interfaces. 2020 Jan 8;12(1):1257-1269. doi: 10.1021/acsami.9b16104. Epub 2019 Dec 18.

PMID:
31802658
3.

Evaluation of Sucrose Laurate as an Intestinal Permeation Enhancer for Macromolecules: Ex Vivo and In Vivo Studies.

McCartney F, Rosa M, Brayden DJ.

Pharmaceutics. 2019 Oct 31;11(11). pii: E565. doi: 10.3390/pharmaceutics11110565.

4.

Labrasol® is an efficacious intestinal permeation enhancer across rat intestine: Ex vivo and in vivo rat studies.

McCartney F, Jannin V, Chevrier S, Boulghobra H, Hristov DR, Ritter N, Miolane C, Chavant Y, Demarne F, Brayden DJ.

J Control Release. 2019 Sep 28;310:115-126. doi: 10.1016/j.jconrel.2019.08.008. Epub 2019 Aug 8.

PMID:
31401199
5.

Stomaching Drug Delivery.

Brayden DJ, Baird AW.

N Engl J Med. 2019 Apr 25;380(17):1671-1673. doi: 10.1056/NEJMcibr1901766. No abstract available.

PMID:
31018074
6.

Intestinal Permeation Enhancers for Oral Delivery of Macromolecules: A Comparison between Salcaprozate Sodium (SNAC) and Sodium Caprate (C10).

Twarog C, Fattah S, Heade J, Maher S, Fattal E, Brayden DJ.

Pharmaceutics. 2019 Feb 13;11(2). pii: E78. doi: 10.3390/pharmaceutics11020078. Review.

7.

Application of Permeation Enhancers in Oral Delivery of Macromolecules: An Update.

Maher S, Brayden DJ, Casettari L, Illum L.

Pharmaceutics. 2019 Jan 19;11(1). pii: E41. doi: 10.3390/pharmaceutics11010041. Review.

8.

Effect of Overencapsulation on the Disintegration and Dissolution of Licensed Formulations for Blinding in Randomized Controlled Trials.

Maher S, Walsh SJ, Takyi J, Wakai A, Brayden DJ, Hayden JC.

J Pharm Sci. 2019 Mar;108(3):1227-1235. doi: 10.1016/j.xphs.2018.10.035. Epub 2018 Oct 29.

PMID:
30385287
9.

Physicochemical, pharmacokinetic and pharmacodynamic analyses of amphiphilic cyclodextrin-based nanoparticles designed to enhance intestinal delivery of insulin.

Presas E, McCartney F, Sultan E, Hunger C, Nellen S, V Alvarez C, Werner U, Bazile D, Brayden DJ, O'Driscoll CM.

J Control Release. 2018 Sep 28;286:402-414. doi: 10.1016/j.jconrel.2018.07.045. Epub 2018 Jul 31.

PMID:
30075208
10.

Intra-articular delivery of a nanocomplex comprising salmon calcitonin, hyaluronic acid, and chitosan using an equine model of joint inflammation.

Sladek S, Kearney C, Crean D, Brama PAJ, Tajber L, Fawcett K, Labberte MC, Leggett B, Brayden DJ.

Drug Deliv Transl Res. 2018 Oct;8(5):1421-1435. doi: 10.1007/s13346-018-0557-x.

PMID:
29947020
11.

TNFα-dependent anhedonia and upregulation of hippocampal serotonin transporter activity in a mouse model of collagen-induced arthritis.

Brown E, Mc Veigh CJ, Santos L, Gogarty M, Müller HK, Elfving B, Brayden DJ, Haase J.

Neuropharmacology. 2018 Jul 15;137:211-220. doi: 10.1016/j.neuropharm.2018.04.023. Epub 2018 May 1.

PMID:
29723540
12.

Track analysis of the passage of rhodamine-labeled liposomes across porcine jejunal mucus in a microchannel device.

Bhattacharjee S, Gaspar MM, Scholz D, Almeida AJ, Brayden DJ.

Ther Deliv. 2018 May 1;9(6):419-433. doi: 10.4155/tde-2017-0116.

PMID:
29722632
13.

Sodium caprate enables the blood pressure-lowering effect of Ile-Pro-Pro and Leu-Lys-Pro in spontaneously hypertensive rats by indirectly overcoming PepT1 inhibition.

Gleeson JP, Frías JM, Ryan SM, Brayden DJ.

Eur J Pharm Biopharm. 2018 Jul;128:179-187. doi: 10.1016/j.ejpb.2018.04.021. Epub 2018 Apr 20.

PMID:
29684535
14.

Labrasol® and Salts of Medium-Chain Fatty Acids Can Be Combined in Low Concentrations to Increase the Permeability of a Macromolecule Marker Across Isolated Rat Intestinal Mucosae.

Heade J, Maher S, Bleiel SB, Brayden DJ.

J Pharm Sci. 2018 Jun;107(6):1648-1655. doi: 10.1016/j.xphs.2018.02.012. Epub 2018 Feb 17.

PMID:
29462634
15.

Effects of surfactant-based permeation enhancers on mannitol permeability, histology, and electrogenic ion transport responses in excised rat colonic mucosae.

Maher S, Heade J, McCartney F, Waters S, Bleiel SB, Brayden DJ.

Int J Pharm. 2018 Mar 25;539(1-2):11-22. doi: 10.1016/j.ijpharm.2018.01.008. Epub 2018 Jan 16.

PMID:
29341916
16.

Editorial overview: New technologies: drug delivery and medical devices combinations, more than the sum of the parts.

Brayden DJ, Hirst BH.

Curr Opin Pharmacol. 2017 Oct;36:iv-vii. doi: 10.1016/j.coph.2017.11.007. No abstract available.

PMID:
29246370
17.

Progress in the formulation and delivery of somatostatin analogs for acromegaly.

Fattah S, Brayden DJ.

Ther Deliv. 2017 Oct;8(10):867-878. doi: 10.4155/tde-2017-0064. Review.

PMID:
28944744
18.

Buccal delivery of small molecules and biologics: of mucoadhesive polymers, films, and nanoparticles.

Morales JO, Brayden DJ.

Curr Opin Pharmacol. 2017 Oct;36:22-28. doi: 10.1016/j.coph.2017.07.011. Epub 2017 Aug 8. Review.

PMID:
28800417
19.

A comparison of three Peyer's patch "M-like" cell culture models: particle uptake, bacterial interaction, and epithelial histology.

Ahmad T, Gogarty M, Walsh EG, Brayden DJ.

Eur J Pharm Biopharm. 2017 Oct;119:426-436. doi: 10.1016/j.ejpb.2017.07.013. Epub 2017 Jul 25.

PMID:
28754262
20.

A human intestinal M-cell-like model for investigating particle, antigen and microorganism translocation.

Beloqui A, Brayden DJ, Artursson P, Préat V, des Rieux A.

Nat Protoc. 2017 Jul;12(7):1387-1399. doi: 10.1038/nprot.2017.041. Epub 2017 Jun 15.

PMID:
28617450

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