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Complementarity of modified NUTRIC score with or without C-reactive protein and subjective global assessment in predicting mortality in critically ill patients.

Oliveira ML, Heyland DK, Silva FM, Rabito EI, Rosa M, Tarnowski MDS, Fernandes D, Marcadenti A.

Rev Bras Ter Intensiva. 2019 Oct-Dec;31(4):490-496. doi: 10.5935/0103-507X.20190086. Portuguese, English.


Lessening Organ dysfunction with VITamin C (LOVIT): protocol for a randomized controlled trial.

Masse MH, Ménard J, Sprague S, Battista MC, Cook DJ, Guyatt GH, Heyland DK, Kanji S, Pinto R, Day AG, Cohen D, Annane D, McGuinness S, Parke R, Carr A, Arabi Y, Vijayaraghavan BKT, D'Aragon F, Carbonneau É, Maslove D, Hunt M, Rochwerg B, Millen T, Chassé M, Lebrasseur M, Archambault P, Deblois E, Drouin C, Lellouche F, Lizotte P, Watpool I, Porteous R, Clarke F, Marinoff N, Belley-Côté É, Bolduc B, Walker S, Iazzetta J, Adhikari NKJ, Lamontagne F; Canadian Critical Care Trials Group.

Trials. 2020 Jan 8;21(1):42. doi: 10.1186/s13063-019-3834-1.


Promotion of Regular Oesophageal Motility to Prevent Regurgitation and Enhance Nutrition Intake in Long-Stay ICU Patients. A Multicenter, Phase II, Sham-Controlled, Randomized Trial: The PROPEL Study.

Heyland DK, Marquis F, Lamontagne F, Albert M, Turgeon AF, Khwaja KA, Garland A, Hall R, Chapman MG, Kutsiogannis DJ, Martin C, Sessler DI, Day AG.

Crit Care Med. 2020 Jan 6. doi: 10.1097/CCM.0000000000004176. [Epub ahead of print]


The plasma peptides of breast versus ovarian cancer.

Dufresne J, Bowden P, Thavarajah T, Florentinus-Mefailoski A, Chen ZZ, Tucholska M, Norzin T, Ho MT, Phan M, Mohamed N, Ravandi A, Stanton E, Slutsky AS, Dos Santos CC, Romaschin A, Marshall JC, Addison C, Malone S, Heyland D, Scheltens P, Killestein J, Teunissen C, Diamandis EP, Siu KWM, Marshall JG.

Clin Proteomics. 2019 Dec 23;16:43. doi: 10.1186/s12014-019-9262-0. eCollection 2019.


A Multicenter Study to Identify Clinician Barriers to Participating in Goals of Care Discussions in Long-term Care.

Siu HYH, Elston D, Arora N, Vahrmeyer A, Kaasalainen S, Chidwick P, Howard M, Heyland DK.

J Am Med Dir Assoc. 2019 Oct 28. pii: S1525-8610(19)30638-3. doi: 10.1016/j.jamda.2019.08.022. [Epub ahead of print]


Supporting shared decision-making about cardiopulmonary resuscitation using a video-based decision-support intervention in a hospital setting: a multisite before-after pilot study.

You JJ, Jayaraman D, Swinton M, Jiang X, Heyland DK.

CMAJ Open. 2019 Oct 25;7(4):E630-E637. doi: 10.9778/cmajo.20190022. Print 2019 Oct-Dec.


Decision support intervention (Plan Well Guide) for patients and their substitute decision-makers to improve engagement in advance care planning: protocol for a randomised trial.

Howard M, Slaven M, Bernard C, Borhan S, Elston D, Arora N, Tan A, Heyland DK.

BMJ Open. 2019 Sep 20;9(9):e027897. doi: 10.1136/bmjopen-2018-027897.


Brief English and Spanish Survey Detects Change in Response to Advance Care Planning Interventions.

Shi Y, Barnes DE, Boscardin J, You JJ, Heyland DK, Volow AM, Howard M, Sudore RL.

J Pain Symptom Manage. 2019 Dec;58(6):1068-1074.e5. doi: 10.1016/j.jpainsymman.2019.09.004. Epub 2019 Sep 18.


Primary care clinicians' confidence, willingness participation and perceptions of roles in advance care planning discussions with patients: a multi-site survey.

Howard M, Langevin J, Bernard C, Tan A, Klein D, Slaven M, Barwich D, Elston D, Arora N, Heyland DK.

Fam Pract. 2019 Sep 19. pii: cmz050. doi: 10.1093/fampra/cmz050. [Epub ahead of print]


Phase 3 Pilot Randomized Controlled Trial Comparing Early Trophic Enteral Nutrition With "No Enteral Nutrition" in Mechanically Ventilated Patients With Septic Shock.

Patel JJ, Kozeniecki M, Peppard WJ, Peppard SR, Zellner-Jones S, Graf J, Szabo A, Heyland DK.

JPEN J Parenter Enteral Nutr. 2019 Sep 19. doi: 10.1002/jpen.1706. [Epub ahead of print]


Effects of Vitamin C on Organ Function in Cardiac Surgery Patients: A Systematic Review and Meta-Analysis.

Hill A, Clasen KC, Wendt S, Majoros ÁG, Stoppe C, Adhikari NKJ, Heyland DK, Benstoem C.

Nutrients. 2019 Sep 4;11(9). pii: E2103. doi: 10.3390/nu11092103.


Family satisfaction with critical care in the UK: a multicentre cohort study.

Ferrando P, Gould DW, Walmsley E, Richards-Belle A, Canter R, Saunders S, Harrison DA, Harvey S, Heyland DK, Hinton L, McColl E, Richardson A, Richardson M, Wright SE, Rowan KM.

BMJ Open. 2019 Aug 20;9(8):e028956. doi: 10.1136/bmjopen-2019-028956.


Enteral Nutrition in Shock: Less May Be More.

Patel JJ, Heyland DK, Rice TW.

Crit Care Med. 2019 Sep;47(9):e794-e795. doi: 10.1097/CCM.0000000000003797. No abstract available.


Nutrition and Exercise in Critical Illness Trial (NEXIS Trial): a protocol of a multicentred, randomised controlled trial of combined cycle ergometry and amino acid supplementation commenced early during critical illness.

Heyland DK, Day A, Clarke GJ, Hough CT, Files DC, Mourtzakis M, Deutz N, Needham DM, Stapleton R.

BMJ Open. 2019 Jul 31;9(7):e027893. doi: 10.1136/bmjopen-2018-027893.


Nutrition support in cardiac surgery patients: Be calm and feed on!

Stoppe C, Whitlock R, Arora RC, Heyland DK.

J Thorac Cardiovasc Surg. 2019 Oct;158(4):1103-1108. doi: 10.1016/j.jtcvs.2019.02.132. Epub 2019 May 7. No abstract available.


Reply-letter to the editor-harm associated with higher energy intake in patients with Low-mNUTRIC score should not be ignored.

Chourdakis M, Heyland DK.

Clin Nutr. 2019 Oct;38(5):2474-2475. doi: 10.1016/j.clnu.2019.04.027. Epub 2019 May 2. No abstract available.


How to achieve nutrition goals by actual nutrition guidelines.

Stoppe C, Preiser JC, Heyland D.

Crit Care. 2019 Jun 13;23(1):216. doi: 10.1186/s13054-019-2502-x. No abstract available.


Do We Have Clinical Equipoise (or Uncertainty) About How Much Protein to Provide to Critically Ill Patients?

Patel JJ, Rice T, Compher C, Heyland DK.

Nutr Clin Pract. 2019 Jun 7. doi: 10.1002/ncp.10320. [Epub ahead of print]


A multicenter, randomized, double-blind study of ulimorelin and metoclopramide in the treatment of critically ill patients with enteral feeding intolerance: PROMOTE trial.

Heyland DK, van Zanten ARH, Grau-Carmona T, Evans D, Beishuizen A, Schouten J, Hoiting O, Bordejé ML, Krell K, Klein DJ, Gonzalez J, Perez A, Brown R, James J, Harris MS; Investigators of the PROMOTE LP101-CL-201 Trial.

Intensive Care Med. 2019 May;45(5):647-656. doi: 10.1007/s00134-019-05593-2. Epub 2019 May 6.


Trends in site of death and health care utilization at the end of life: a population-based cohort study.

Hill AD, Stukel TA, Fu L, Scales DC, Laupacis A, Rubenfeld GD, Wunsch H, Downar J, Rockwood K, Heyland DK, Sinha SK, Zimmermann C, Gandhi S, Myers J, Ross HJ, Kozak JF, Berry S, Dev SP, La Delfa I, Fowler RA.

CMAJ Open. 2019 Apr 26;7(2):E306-E315. doi: 10.9778/cmajo.20180097. Print 2019 Apr-Jun.

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