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Items: 17


A Key Role for Prefrontocortical Small Conductance Calcium-Activated Potassium Channels in Stress Adaptation and Rapid Antidepressant Response.

Bambico FR, Li Z, Creed M, De Gregorio D, Diwan M, Li J, McNeill S, Gobbi G, Raymond R, Nobrega JN.

Cereb Cortex. 2019 Sep 3. pii: bhz187. doi: 10.1093/cercor/bhz187. [Epub ahead of print]


Characterization of the sensory, affective, cognitive, biochemical, and neuronal alterations in a modified chronic constriction injury model of neuropathic pain in mice.

Medeiros P, de Freitas RL, Boccella S, Iannotta M, Belardo C, Mazzitelli M, Romano R, De Gregorio D, Coimbra NC, Palazzo E, Maione S.

J Neurosci Res. 2020 Feb;98(2):338-352. doi: 10.1002/jnr.24501. Epub 2019 Aug 8.


Melatonin MT1 and MT2 Receptors Exhibit Distinct Effects in the Modulation of Body Temperature across the Light/Dark Cycle.

López-Canul M, Min SH, Posa L, De Gregorio D, Bedini A, Spadoni G, Gobbi G, Comai S.

Int J Mol Sci. 2019 May 17;20(10). pii: E2452. doi: 10.3390/ijms20102452.


Melatonin MT1 receptor as a novel target in neuropsychopharmacology: MT1 ligands, pathophysiological and therapeutic implications, and perspectives.

Comai S, Lopez-Canul M, De Gregorio D, Posner A, Ettaoussi M, Guarnieri FC, Gobbi G.

Pharmacol Res. 2019 Jun;144:343-356. doi: 10.1016/j.phrs.2019.04.015. Epub 2019 Apr 25. Review.


d-Lysergic acid diethylamide, psilocybin, and other classic hallucinogens: Mechanism of action and potential therapeutic applications in mood disorders.

De Gregorio D, Enns JP, Nuñez NA, Posa L, Gobbi G.

Prog Brain Res. 2018;242:69-96. doi: 10.1016/bs.pbr.2018.07.008. Epub 2018 Aug 31. Review.


Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain.

De Gregorio D, McLaughlin RJ, Posa L, Ochoa-Sanchez R, Enns J, Lopez-Canul M, Aboud M, Maione S, Comai S, Gobbi G.

Pain. 2019 Jan;160(1):136-150. doi: 10.1097/j.pain.0000000000001386.


Ketones and pain: unexplored role of hydroxyl carboxylic acid receptor type 2 in the pathophysiology of neuropathic pain.

Boccella S, Guida F, De Logu F, De Gregorio D, Mazzitelli M, Belardo C, Iannotta M, Serra N, Nassini R, de Novellis V, Geppetti P, Maione S, Luongo L.

FASEB J. 2019 Jan;33(1):1062-1073. doi: 10.1096/fj.201801033R. Epub 2018 Aug 7.


Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E.

Aguilar-Valles A, Haji N, De Gregorio D, Matta-Camacho E, Eslamizade MJ, Popic J, Sharma V, Cao R, Rummel C, Tanti A, Wiebe S, Nuñez N, Comai S, Nadon R, Luheshi G, Mechawar N, Turecki G, Lacaille JC, Gobbi G, Sonenberg N.

Nat Commun. 2018 Jun 25;9(1):2459. doi: 10.1038/s41467-018-04883-5.


Palmitoylethanolamide Reduces Neuropsychiatric Behaviors by Restoring Cortical Electrophysiological Activity in a Mouse Model of Mild Traumatic Brain Injury.

Guida F, Boccella S, Iannotta M, De Gregorio D, Giordano C, Belardo C, Romano R, Palazzo E, Scafuro MA, Serra N, de Novellis V, Rossi F, Maione S, Luongo L.

Front Pharmacol. 2017 Mar 6;8:95. doi: 10.3389/fphar.2017.00095. eCollection 2017.


Targeting Melatonin MT2 Receptors: A Novel Pharmacological Avenue for Inflammatory and Neuropathic Pain.

Posa L, De Gregorio D, Gobbi G, Comai S.

Curr Med Chem. 2018;25(32):3866-3882. doi: 10.2174/0929867324666170209104926. Review.


d-Lysergic Acid Diethylamide (LSD) as a Model of Psychosis: Mechanism of Action and Pharmacology.

De Gregorio D, Comai S, Posa L, Gobbi G.

Int J Mol Sci. 2016 Nov 23;17(11). pii: E1953. Review.


The hallucinogen d-lysergic diethylamide (LSD) decreases dopamine firing activity through 5-HT1A, D2 and TAAR1 receptors.

De Gregorio D, Posa L, Ochoa-Sanchez R, McLaughlin R, Maione S, Comai S, Gobbi G.

Pharmacol Res. 2016 Nov;113(Pt A):81-91. doi: 10.1016/j.phrs.2016.08.022. Epub 2016 Aug 17.


Genetic deletion of monoacylglycerol lipase leads to impaired cannabinoid receptor CB₁R signaling and anxiety-like behavior.

Imperatore R, Morello G, Luongo L, Taschler U, Romano R, De Gregorio D, Belardo C, Maione S, Di Marzo V, Cristino L.

J Neurochem. 2015 Nov;135(4):799-813. doi: 10.1111/jnc.13267. Epub 2015 Sep 11.


MMPIP, an mGluR7-selective negative allosteric modulator, alleviates pain and normalizes affective and cognitive behavior in neuropathic mice.

Palazzo E, Romano R, Luongo L, Boccella S, De Gregorio D, Giordano ME, Rossi F, Marabese I, Scafuro MA, de Novellis V, Maione S.

Pain. 2015 Jun;156(6):1060-73. doi: 10.1097/j.pain.0000000000000150.


Effects of metabolites of the analgesic agent dipyrone (metamizol) on rostral ventromedial medulla cell activity in mice.

Maione S, Radanova L, De Gregorio D, Luongo L, De Petrocellis L, Di Marzo V, Imming P.

Eur J Pharmacol. 2015 Feb 5;748:115-22. doi: 10.1016/j.ejphar.2014.12.022. Epub 2014 Dec 31.


Dorsal striatum metabotropic glutamate receptor 8 affects nocifensive responses and rostral ventromedial medulla cell activity in neuropathic pain conditions.

Rossi F, Marabese I, De Chiaro M, Boccella S, Luongo L, Guida F, De Gregorio D, Giordano C, de Novellis V, Palazzo E, Maione S.

J Neurophysiol. 2014 Jun 1;111(11):2196-209. doi: 10.1152/jn.00212.2013. Epub 2013 Dec 4.

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