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Items: 1 to 20 of 144

1.

New insights into the opening of the occluded ligand-binding pocket of Sigma1 receptor: binding of a novel bivalent RC-33 derivative.

Rossino G, Orellana I, Caballero J, Schepmann D, Wünsch B, Rui M, Rossi D, Gonzalez-Avendaño M, Collina S, Vergara-Jaque A.

J Chem Inf Model. 2019 Dec 6. doi: 10.1021/acs.jcim.9b00649. [Epub ahead of print]

PMID:
31809025
2.

ALS-Associated SOD1(G93A) Decreases SERCA Pump Levels and Increases Store-Operated Ca2+ Entry in Primary Spinal Cord Astrocytes from a Transgenic Mouse Model.

Norante RP, Peggion C, Rossi D, Martorana F, De Mario A, Lia A, Massimino ML, Bertoli A.

Int J Mol Sci. 2019 Oct 17;20(20). pii: E5151. doi: 10.3390/ijms20205151.

3.

Astrocytes in Motor Neuron Diseases.

Valori CF, Guidotti G, Brambilla L, Rossi D.

Adv Exp Med Biol. 2019;1175:227-272. doi: 10.1007/978-981-13-9913-8_10. Review.

PMID:
31583591
4.

Nailfold Capillaroscopy Patterns.

Rossi D, Sciascia S, Roccatello D.

Isr Med Assoc J. 2019 Jul;21(7):497-498. No abstract available.

5.

A novel homozygous mutation in the TRDN gene causes a severe form of pediatric malignant ventricular arrhythmia.

Rossi D, Gigli L, Gamberucci A, Bordoni R, Pietrelli A, Lorenzini S, Pierantozzi E, Peretto G, De Bellis G, Della Bella P, Ferrari M, Sorrentino V, Benedetti S, Sala S, Di Resta C.

Heart Rhythm. 2019 Aug 19. pii: S1547-5271(19)30750-7. doi: 10.1016/j.hrthm.2019.08.018. [Epub ahead of print]

PMID:
31437535
6.

Calcium Homeostasis Is Modified in Skeletal Muscle Fibers of Small Ankyrin1 Knockout Mice.

Pierantozzi E, Szentesi P, Al-Gaadi D, Oláh T, Dienes B, Sztretye M, Rossi D, Sorrentino V, Csernoch L.

Int J Mol Sci. 2019 Jul 9;20(13). pii: E3361. doi: 10.3390/ijms20133361.

7.

Molecular determinants of homo- and heteromeric interactions of Junctophilin-1 at triads in adult skeletal muscle fibers.

Rossi D, Scarcella AM, Liguori E, Lorenzini S, Pierantozzi E, Kutchukian C, Jacquemond V, Messa M, De Camilli P, Sorrentino V.

Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15716-15724. doi: 10.1073/pnas.1820980116. Epub 2019 Jul 17.

PMID:
31315980
8.

Functional Electrical Stimulation: A Possible Strategy to Improve Muscle Function in Central Core Disease?

Iodice P, Boncompagni S, Pietrangelo L, Galli L, Pierantozzi E, Rossi D, Fusella A, Caulo M, Kern H, Sorrentino V, Protasi F.

Front Neurol. 2019 May 29;10:479. doi: 10.3389/fneur.2019.00479. eCollection 2019.

9.

Anti-tumor Efficacy Assessment of the Sigma Receptor Pan Modulator RC-106. A Promising Therapeutic Tool for Pancreatic Cancer.

Tesei A, Cortesi M, Pignatta S, Arienti C, Dondio GM, Bigogno C, Malacrida A, Miloso M, Meregalli C, Chiorazzi A, Carozzi V, Cavaletti G, Rui M, Marra A, Rossi D, Collina S.

Front Pharmacol. 2019 May 14;10:490. doi: 10.3389/fphar.2019.00490. eCollection 2019.

10.

Astrocytes: Emerging Therapeutic Targets in Neurological Disorders.

Valori CF, Guidotti G, Brambilla L, Rossi D.

Trends Mol Med. 2019 Sep;25(9):750-759. doi: 10.1016/j.molmed.2019.04.010. Epub 2019 May 20. Review.

PMID:
31122805
11.

Novel Compounds Targeting the RNA-Binding Protein HuR. Structure-Based Design, Synthesis, and Interaction Studies.

Della Volpe S, Nasti R, Queirolo M, Unver MY, Jumde VK, Dömling A, Vasile F, Potenza D, Ambrosio FA, Costa G, Alcaro S, Zucal C, Provenzani A, Di Giacomo M, Rossi D, Hirsch AKH, Collina S.

ACS Med Chem Lett. 2019 Jan 21;10(4):615-620. doi: 10.1021/acsmedchemlett.8b00600. eCollection 2019 Apr 11.

PMID:
30996806
12.

Peptides in clinical development for the treatment of brain tumors.

Guidotti G, Brambilla L, Rossi D.

Curr Opin Pharmacol. 2019 Aug;47:102-109. doi: 10.1016/j.coph.2019.02.007. Epub 2019 Apr 5. Review.

PMID:
30959356
13.

DHFR Inhibitors: Reading the Past for Discovering Novel Anticancer Agents.

Raimondi MV, Randazzo O, La Franca M, Barone G, Vignoni E, Rossi D, Collina S.

Molecules. 2019 Mar 22;24(6). pii: E1140. doi: 10.3390/molecules24061140. Review.

14.

The use of a microwave-assisted solvent extraction coupled with HPLC-UV/PAD to assess the quality of Marrubium vulgare L. (white horehound) herbal raw material.

Martino E, Della Volpe S, Cavalloro V, Amri B, Kaab LBB, Marrubini G, Rossi D, Collina S.

Phytochem Anal. 2019 Jul;30(4):377-384. doi: 10.1002/pca.2820. Epub 2019 Jan 27.

PMID:
30687967
15.

Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents.

Rui M, Rossino G, Coniglio S, Monteleone S, Scuteri A, Malacrida A, Rossi D, Catenacci L, Sorrenti M, Paolillo M, Curti D, Venturini L, Schepmann D, Wünsch B, Liedl KR, Cavaletti G, Pace V, Urban E, Collina S.

Eur J Med Chem. 2018 Oct 5;158:353-370. doi: 10.1016/j.ejmech.2018.09.010. Epub 2018 Sep 8.

PMID:
30223122
16.

Exploration of ligand binding modes towards the identification of compounds targeting HuR: a combined STD-NMR and Molecular Modelling approach.

Vasile F, Della Volpe S, Ambrosio FA, Costa G, Unver MY, Zucal C, Rossi D, Martino E, Provenzani A, Hirsch AKH, Alcaro S, Potenza D, Collina S.

Sci Rep. 2018 Sep 13;8(1):13780. doi: 10.1038/s41598-018-32084-z.

17.

Dysregulation of Astrocytic HMGB1 Signaling in Amyotrophic Lateral Sclerosis.

Brambilla L, Martorana F, Guidotti G, Rossi D.

Front Neurosci. 2018 Aug 29;12:622. doi: 10.3389/fnins.2018.00622. eCollection 2018.

18.

Studies on enantioselectivity of chiral 4-acetylamino-6-alkyloxy-2-alkylthiopyrimidines acting as antagonists of the human A3 adenosine receptor.

Cosimelli B, Greco G, Laneri S, Novellino E, Sacchi A, Collina S, Rossi D, Cosconati S, Barresi E, Taliani S, Trincavelli ML, Martini C.

Medchemcomm. 2017 Nov 9;9(1):81-86. doi: 10.1039/c7md00375g. eCollection 2018 Jan 1.

19.

Sigma Receptors as Endoplasmic Reticulum Stress "Gatekeepers" and their Modulators as Emerging New Weapons in the Fight Against Cancer.

Tesei A, Cortesi M, Zamagni A, Arienti C, Pignatta S, Zanoni M, Paolillo M, Curti D, Rui M, Rossi D, Collina S.

Front Pharmacol. 2018 Jul 10;9:711. doi: 10.3389/fphar.2018.00711. eCollection 2018. Review.

20.

A Role for GDNF and Soluble APP as Biomarkers of Amyotrophic Lateral Sclerosis Pathophysiology.

Stanga S, Brambilla L, Tasiaux B, Dang AH, Ivanoiu A, Octave JN, Rossi D, van Pesch V, Kienlen-Campard P.

Front Neurol. 2018 May 30;9:384. doi: 10.3389/fneur.2018.00384. eCollection 2018.

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