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Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data.

Krebs A, Waldmann T, Wilks MF, Van Vugt-Lussenburg BMA, Van der Burg B, Terron A, Steger-Hartmann T, Ruegg J, Rovida C, Pedersen E, Pallocca G, Luijten M, Leite SB, Kustermann S, Kamp H, Hoeng J, Hewitt P, Herzler M, Hengstler JG, Heinonen T, Hartung T, Hardy B, Gantner F, Fritsche E, Fant K, Ezendam J, Exner T, Dunkern T, Dietrich DR, Coecke S, Busquet F, Braeuning A, Bondarenko O, Bennekou SH, Beilmann M, Leist M.

ALTEX. 2019;36(4):682-699. doi: 10.14573/altex.1909271.


Machine learning prediction of cyanobacterial toxin (microcystin) toxicodynamics in humans.

Altaner S, Jaeger S, Fotler R, Zemskov I, Wittmann V, Schreiber F, Dietrich DR.

ALTEX. 2019 Jul 2. doi: 10.14573/altex.1904031. [Epub ahead of print]


Simultaneous Detection of 14 Microcystin Congeners from Tissue Samples Using UPLC- ESI-MS/MS and Two Different Deuterated Synthetic Microcystins as Internal Standards.

Altaner S, Puddick J, Fessard V, Feurstein D, Zemskov I, Wittmann V, Dietrich DR.

Toxins (Basel). 2019 Jul 2;11(7). pii: E388. doi: 10.3390/toxins11070388.


Functional transepithelial transport measurements to detect nephrotoxicity in vitro using the RPTEC/TERT1 cell line.

Secker PF, Schlichenmaier N, Beilmann M, Deschl U, Dietrich DR.

Arch Toxicol. 2019 Jul;93(7):1965-1978. doi: 10.1007/s00204-019-02469-8. Epub 2019 May 10.


Comparison of Aristolochic acid I derived DNA adduct levels in human renal toxicity models.

Bastek H, Zubel T, Stemmer K, Mangerich A, Beneke S, Dietrich DR.

Toxicology. 2019 May 15;420:29-38. doi: 10.1016/j.tox.2019.03.013. Epub 2019 Mar 30.


Toxic Cyanobacteria in Svalbard: Chemical Diversity of Microcystins Detected Using a Liquid Chromatography Mass Spectrometry Precursor Ion Screening Method.

Kleinteich J, Puddick J, Wood SA, Hildebrand F, Laughinghouse HD IV, Pearce DA, Dietrich DR, Wilmotte A.

Toxins (Basel). 2018 Apr 3;10(4). pii: E147. doi: 10.3390/toxins10040147.


Canagliflozin mediated dual inhibition of mitochondrial glutamate dehydrogenase and complex I: an off-target adverse effect.

Secker PF, Beneke S, Schlichenmaier N, Delp J, Gutbier S, Leist M, Dietrich DR.

Cell Death Dis. 2018 Feb 14;9(2):226. doi: 10.1038/s41419-018-0273-y.


Identification of d-amino acid oxidase and propiverine interaction partners and their potential role in the propiverine-mediated nephropathy.

Maier MY, Luks L, Baudendistel OR, Wittmann V, Dietrich DR.

Chem Biol Interact. 2018 Feb 1;281:69-80. doi: 10.1016/j.cbi.2017.12.023. Epub 2017 Dec 19.


RPTEC/TERT1 cells form highly differentiated tubules when cultured in a 3D matrix.

Secker PF, Luks L, Schlichenmaier N, Dietrich DR.

ALTEX. 2018;35(2):223-234. doi: 10.14573/altex.1710181. Epub 2017 Dec 2.


Further thoughts on limitations, uncertainties and competing interpretations regarding chemical exposures and diabetes.

Bond GG, Dietrich DR.

J Epidemiol Community Health. 2017 Sep;71(9):943. doi: 10.1136/jech-2017-209451. Epub 2017 Jul 8. No abstract available.


Human cost burden of exposure to endocrine disrupting chemicals. A critical review.

Bond GG, Dietrich DR.

Arch Toxicol. 2017 Aug;91(8):2745-2762. doi: 10.1007/s00204-017-1985-y. Epub 2017 May 20. Review.


Understanding renal nuclear protein accumulation: an in vitro approach to explain an in vivo phenomenon.

Luks L, Maier MY, Sacchi S, Pollegioni L, Dietrich DR.

Arch Toxicol. 2017 Nov;91(11):3599-3611. doi: 10.1007/s00204-017-1970-5. Epub 2017 Apr 27.


Adsorption of Ten Microcystin Congeners to Common Laboratory-Ware Is Solvent and Surface Dependent.

Altaner S, Puddick J, Wood SA, Dietrich DR.

Toxins (Basel). 2017 Apr 6;9(4). pii: E129. doi: 10.3390/toxins9040129.


Time-matched analysis of DNA adduct formation and early gene expression as predictive tool for renal carcinogenesis in methylazoxymethanol acetate treated Eker rats.

Klaus V, Bastek H, Damme K, Collins LB, Frötschl R, Benda N, Lutter D, Ellinger-Ziegelbauer H, Swenberg JA, Dietrich DR, Stemmer K.

Arch Toxicol. 2017 Oct;91(10):3427-3438. doi: 10.1007/s00204-017-1953-6. Epub 2017 Mar 27.


Total Synthesis of Microcystin-LF and Derivatives Thereof.

Zemskov I, Altaner S, Dietrich DR, Wittmann V.

J Org Chem. 2017 Apr 7;82(7):3680-3691. doi: 10.1021/acs.joc.7b00175. Epub 2017 Mar 27.


Limitations, uncertainties and competing interpretations regarding chemical exposures and diabetes.

Bond GG, Dietrich DR.

J Epidemiol Community Health. 2017 Sep;71(9):941. doi: 10.1136/jech-2016-208711. Epub 2017 Mar 6. No abstract available.


Trophic state and geographic gradients influence planktonic cyanobacterial diversity and distribution in New Zealand lakes.

Wood SA, Maier MY, Puddick J, Pochon X, Zaiko A, Dietrich DR, Hamilton DP.

FEMS Microbiol Ecol. 2017 Feb;93(2). pii: fiw234. Epub 2016 Nov 16.


Allowing pseudoscience into EU risk assessment processes is eroding public trust in science experts and in science as a whole: The bigger picture.

Dietrich DR, Dekant W, Greim H, Heslop-Harrison P, Berry SC, Boobis A, Hengstler J, Sharpe R.

Chem Biol Interact. 2016 Sep 25;257:1-3. doi: 10.1016/j.cbi.2016.07.023. Epub 2016 Jul 21. No abstract available.


EU safety regulations: Don't mar legislation with pseudoscience.

Dietrich DR.

Nature. 2016 Jul 21;535(7612):355. doi: 10.1038/535355c. No abstract available.


Conflict of interest statements: current dilemma and a possible way forward.

Dietrich DR, Hengstler JG.

Arch Toxicol. 2016 Sep;90(9):2293-2295. doi: 10.1007/s00204-016-1783-y. No abstract available.


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