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Items: 1 to 20 of 47

1.

Glutathione precursors shield the brain from trauma.

Koza L, Linseman DA.

Neural Regen Res. 2019 Oct;14(10):1701-1702. doi: 10.4103/1673-5374.257520. No abstract available.

2.

Neuroprotection Comparison of Rosmarinic Acid and Carnosic Acid in Primary Cultures of Cerebellar Granule Neurons.

Taram F, Ignowski E, Duval N, Linseman DA.

Molecules. 2018 Nov 13;23(11). pii: E2956. doi: 10.3390/molecules23112956.

3.

The cysteine-rich whey protein supplement, Immunocal®, preserves brain glutathione and improves cognitive, motor, and histopathological indices of traumatic brain injury in a mouse model of controlled cortical impact.

Ignowski E, Winter AN, Duval N, Fleming H, Wallace T, Manning E, Koza L, Huber K, Serkova NJ, Linseman DA.

Free Radic Biol Med. 2018 Aug 20;124:328-341. doi: 10.1016/j.freeradbiomed.2018.06.026. Epub 2018 Jun 27.

PMID:
29940352
4.

The Bcl-2 Homology-3 Domain (BH3)-Only Proteins, Bid, DP5/Hrk, and BNip3L, Are Upregulated in Reactive Astrocytes of End-Stage Mutant SOD1 Mouse Spinal Cord.

Duval N, Sumner WA, Andrianakos AG, Gray JJ, Bouchard RJ, Wilkins HM, Linseman DA.

Front Cell Neurosci. 2018 Jan 30;12:15. doi: 10.3389/fncel.2018.00015. eCollection 2018.

5.

Procyanidin B2 Protects Neurons from Oxidative, Nitrosative, and Excitotoxic Stress.

Sutcliffe TC, Winter AN, Punessen NC, Linseman DA.

Antioxidants (Basel). 2017 Oct 13;6(4). pii: E77. doi: 10.3390/antiox6040077.

6.

A Cystine-Rich Whey Supplement (Immunocal®) Provides Neuroprotection from Diverse Oxidative Stress-Inducing Agents In Vitro by Preserving Cellular Glutathione.

Winter AN, Ross EK, Daliparthi V, Sumner WA, Kirchhof DM, Manning E, Wilkins HM, Linseman DA.

Oxid Med Cell Longev. 2017;2017:3103272. doi: 10.1155/2017/3103272. Epub 2017 Aug 15.

7.

Comparison of the Neuroprotective and Anti-Inflammatory Effects of the Anthocyanin Metabolites, Protocatechuic Acid and 4-Hydroxybenzoic Acid.

Winter AN, Brenner MC, Punessen N, Snodgrass M, Byars C, Arora Y, Linseman DA.

Oxid Med Cell Longev. 2017;2017:6297080. doi: 10.1155/2017/6297080. Epub 2017 Jun 27.

8.

An anthocyanin-enriched extract from strawberries delays disease onset and extends survival in the hSOD1G93A mouse model of amyotrophic lateral sclerosis.

Winter AN, Ross EK, Wilkins HM, Stankiewicz TR, Wallace T, Miller K, Linseman DA.

Nutr Neurosci. 2018 Jul;21(6):414-426. doi: 10.1080/1028415X.2017.1297023. Epub 2017 Mar 9.

PMID:
28276271
9.

Chemical basis for the disparate neuroprotective effects of the anthocyanins, callistephin and kuromanin, against nitrosative stress.

Winter AN, Ross EK, Khatter S, Miller K, Linseman DA.

Free Radic Biol Med. 2017 Feb;103:23-34. doi: 10.1016/j.freeradbiomed.2016.12.012. Epub 2016 Dec 13.

PMID:
27986528
10.

Neuroprotection comparison of chlorogenic acid and its metabolites against mechanistically distinct cell death-inducing agents in cultured cerebellar granule neurons.

Taram F, Winter AN, Linseman DA.

Brain Res. 2016 Oct 1;1648(Pt A):69-80. doi: 10.1016/j.brainres.2016.07.028. Epub 2016 Jul 18.

PMID:
27444557
11.

Neuronal apoptosis induced by selective inhibition of Rac GTPase versus global suppression of Rho family GTPases is mediated by alterations in distinct mitogen-activated protein kinase signaling cascades.

Stankiewicz TR, Ramaswami SA, Bouchard RJ, Aktories K, Linseman DA.

J Biol Chem. 2015 Apr 10;290(15):9363-76. doi: 10.1074/jbc.M114.575217. Epub 2015 Feb 9.

12.

Mitochondrial lysates induce inflammation and Alzheimer's disease-relevant changes in microglial and neuronal cells.

Wilkins HM, Carl SM, Weber SG, Ramanujan SA, Festoff BW, Linseman DA, Swerdlow RH.

J Alzheimers Dis. 2015;45(1):305-18. doi: 10.3233/JAD-142334.

13.

C-terminal binding proteins: central players in development and disease.

Stankiewicz TR, Gray JJ, Winter AN, Linseman DA.

Biomol Concepts. 2014 Dec;5(6):489-511. doi: 10.1515/bmc-2014-0027. Review.

PMID:
25429601
14.

Rho family GTPases: key players in neuronal development, neuronal survival, and neurodegeneration.

Stankiewicz TR, Linseman DA.

Front Cell Neurosci. 2014 Oct 7;8:314. doi: 10.3389/fncel.2014.00314. eCollection 2014. Review.

15.

Monitoring of single vesicle cytochrome-c release illuminates BAK as a novel target of Aβ oligomers.

Linseman DA.

Biophys J. 2014 Oct 7;107(7):1491-2. doi: 10.1016/j.bpj.2014.08.012. No abstract available.

16.

Stable over-expression of the 2-oxoglutarate carrier enhances neuronal cell resistance to oxidative stress via Bcl-2-dependent mitochondrial GSH transport.

Wilkins HM, Brock S, Gray JJ, Linseman DA.

J Neurochem. 2014 Jul;130(1):75-86. doi: 10.1111/jnc.12709. Epub 2014 Apr 2.

17.

A Cystine-Rich Whey Supplement (Immunocal(®)) Delays Disease Onset and Prevents Spinal Cord Glutathione Depletion in the hSOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis.

Ross EK, Winter AN, Wilkins HM, Sumner WA, Duval N, Patterson D, Linseman DA.

Antioxidants (Basel). 2014 Dec 12;3(4):843-65. doi: 10.3390/antiox3040843.

18.

C-terminal binding proteins are essential pro-survival factors that undergo caspase-dependent downregulation during neuronal apoptosis.

Stankiewicz TR, Schroeder EK, Kelsey NA, Bouchard RJ, Linseman DA.

Mol Cell Neurosci. 2013 Sep;56:322-332. doi: 10.1016/j.mcn.2013.07.004. Epub 2013 Jul 13.

19.

Mitochondrial glutathione transport is a key determinant of neuronal susceptibility to oxidative and nitrosative stress.

Wilkins HM, Kirchhof D, Manning E, Joseph JW, Linseman DA.

J Biol Chem. 2013 Feb 15;288(7):5091-101. doi: 10.1074/jbc.M112.405738. Epub 2013 Jan 2.

20.

N-terminal cleavage of the mitochondrial fusion GTPase OPA1 occurs via a caspase-independent mechanism in cerebellar granule neurons exposed to oxidative or nitrosative stress.

Gray JJ, Zommer AE, Bouchard RJ, Duval N, Blackstone C, Linseman DA.

Brain Res. 2013 Feb 4;1494:28-43. doi: 10.1016/j.brainres.2012.12.001. Epub 2012 Dec 7.

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