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Nutrients. 2018 Aug 25;10(9). pii: E1168. doi: 10.3390/nu10091168.

Flavonoids, Potential Bioactive Compounds, and Non-Shivering Thermogenesis.

Author information

1
Food and Nutritional Sciences, Department of Family and Consumer Sciences, North Carolina Agricultural and Technical State University, Greensboro, NC 27411, USA. hkang@ncat.edu.
2
Department of Food Science and Nutrition, Pukyong National University, Busan, 48513, Korea. sglee1125@pknu.ac.kr.
3
Department of Applied Science and Technology, North Carolina Agricultural and Technical State University, Greensboro, NC 27411, USA. dotieno@aggies.ncat.edu.
4
Food and Nutritional Sciences, Department of Family and Consumer Sciences, North Carolina Agricultural and Technical State University, Greensboro, NC 27411, USA. kha@ncat.edu.

Abstract

Obesity results from the body having either high energy intake or low energy expenditure. Based on this energy equation, scientists have focused on increasing energy expenditure to prevent abnormal fat accumulation. Activating the human thermogenic system that regulates body temperature, particularly non-shivering thermogenesis in either brown or white adipose tissue, has been suggested as a promising solution to increase energy expenditure. Together with the increasing interest in understanding the mechanism by which plant-derived dietary compounds prevent obesity, flavonoids were recently shown to have the potential to regulate non-shivering thermogenesis. In this article, we review the latest research on flavonoid derivatives that increase energy expenditure through non-shivering thermogenesis.

KEYWORDS:

beige adipocytes; brown adipose tissue; flavonoids; non-shivering thermogenesis; obesity

PMID:
30149637
PMCID:
PMC6164844
DOI:
10.3390/nu10091168
[Indexed for MEDLINE]
Free PMC Article

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