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Items: 1 to 20 of 46

1.

Marine-Derived Natural Lead Compound Disulfide-Linked Dimer Psammaplin A: Biological Activity and Structural Modification.

Jing Q, Hu X, Ma Y, Mu J, Liu W, Xu F, Li Z, Bai J, Hua H, Li D.

Mar Drugs. 2019 Jun 27;17(7). pii: E384. doi: 10.3390/md17070384. Review.

2.

Hydrogen sulfide donating ent-kaurane and spirolactone-type 6,7-seco-ent-kaurane derivatives: Design, synthesis and antiproliferative properties.

Li H, Gao X, Huang X, Wang X, Xu S, Uchita T, Gao M, Xu J, Hua H, Li D.

Eur J Med Chem. 2019 Sep 15;178:446-457. doi: 10.1016/j.ejmech.2019.06.016. Epub 2019 Jun 6.

PMID:
31202992
3.

A pair of new enantiomers of xanthones from the stems and leaves of Cratoxylum cochinchinense.

Jia C, Gong C, Chen H, Pu J, Li D, Li Z, Hua H.

Chin Med. 2019 Mar 29;14:14. doi: 10.1186/s13020-019-0235-z. eCollection 2019.

4.

Effective enmein-type mimics of clinical candidate HAO472: Design, synthesis and biological evaluation.

Hu X, Bai Z, Qiao J, Li H, Xu S, Wang X, Xu Y, Xu J, Hua H, Li D.

Eur J Med Chem. 2019 Jun 1;171:169-179. doi: 10.1016/j.ejmech.2019.03.046. Epub 2019 Mar 21.

PMID:
30921757
5.

New benzyl-aporphine alkaloids from Thalictrum cultratum.

Kang W, Li J, Li D, Li Z, Chen S, Hua H, Bai J.

Nat Prod Res. 2018 Dec 22:1-4. doi: 10.1080/14786419.2018.1523160. [Epub ahead of print]

PMID:
30580597
6.

Bioactive Natural Spirolactone-Type 6,7-seco-ent-Kaurane Diterpenoids and Synthetic Derivatives.

Li H, Jiao R, Mu J, Xu S, Li X, Wang X, Li Z, Xu J, Hua H, Li D.

Molecules. 2018 Nov 8;23(11). pii: E2914. doi: 10.3390/molecules23112914. Review.

7.

Antiproliferative Effects of Alkaloid Evodiamine and Its Derivatives.

Hu X, Li D, Chu C, Li X, Wang X, Jia Y, Hua H, Xu F.

Int J Mol Sci. 2018 Oct 30;19(11). pii: E3403. doi: 10.3390/ijms19113403. Review.

8.

Hydrogen sulfide releasing enmein-type diterpenoid derivatives as apoptosis inducers through mitochondria-related pathways.

Xu F, Gao X, Li H, Xu S, Li X, Hu X, Li Z, Xu J, Hua H, Li D.

Bioorg Chem. 2019 Feb;82:192-203. doi: 10.1016/j.bioorg.2018.10.002. Epub 2018 Oct 8.

PMID:
30326401
9.

Synthesis of scutellarein derivatives with antiproliferative activity and selectivity through the intrinsic pathway.

Han T, Wang Y, Wang M, Li X, Cheng K, Gao X, Li Z, Bai J, Hua H, Li D.

Eur J Med Chem. 2018 Oct 5;158:493-501. doi: 10.1016/j.ejmech.2018.09.047. Epub 2018 Sep 18.

PMID:
30243153
10.

Bioactive enmein-type 6,7-seco-ent-kaurane diterpenoids: natural products, synthetic derivatives and apoptosis related mechanism.

Li H, Sun B, Wang M, Hu X, Gao X, Xu S, Xu Y, Xu J, Hua H, Li D.

Arch Pharm Res. 2018 Nov;41(11):1051-1061. doi: 10.1007/s12272-018-1078-3. Epub 2018 Sep 21. Review.

PMID:
30242610
11.

New depsidone and dichromone from the stems of Garcinia paucinervis with antiproliferative activity.

Jia C, Xue J, Li X, Li D, Li Z, Hua H.

J Nat Med. 2019 Jan;73(1):278-282. doi: 10.1007/s11418-018-1247-1. Epub 2018 Sep 4.

PMID:
30182180
12.

Silibinin decreases hepatic glucose production through the activation of gut-brain-liver axis in diabetic rats.

Xu F, Yang J, Negishi H, Sun Y, Li D, Zhang X, Hayashi T, Gao M, Ikeda K, Ikejima T.

Food Funct. 2018 Sep 19;9(9):4926-4935. doi: 10.1039/c8fo00565f.

PMID:
30178798
13.

Identification of flavonolignans from Silybum marianum seeds as allosteric protein tyrosine phosphatase 1B inhibitors.

Qin N, Sasaki T, Li W, Wang J, Zhang X, Li D, Li Z, Cheng M, Hua H, Koike K.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):1283-1291. doi: 10.1080/14756366.2018.1497020.

14.

OsRACK1A, encodes a circadian clock-regulated WD40 protein, negatively affect salt tolerance in rice.

Zhang D, Wang Y, Shen J, Yin J, Li D, Gao Y, Xu W, Liang J.

Rice (N Y). 2018 Aug 2;11(1):45. doi: 10.1186/s12284-018-0232-3.

15.

Diterpenoid lead stevioside and its hydrolysis products steviol and isosteviol: Biological activity and structural modification.

Wang M, Li H, Xu F, Gao X, Li J, Xu S, Zhang D, Wu X, Xu J, Hua H, Li D.

Eur J Med Chem. 2018 Aug 5;156:885-906. doi: 10.1016/j.ejmech.2018.07.052. Epub 2018 Jul 24. Review.

PMID:
30059803
16.

Role of silibinin in the management of diabetes mellitus and its complications.

Chu C, Li D, Zhang S, Ikejima T, Jia Y, Wang D, Xu F.

Arch Pharm Res. 2018 Aug;41(8):785-796. doi: 10.1007/s12272-018-1047-x. Epub 2018 Jul 6. Review.

PMID:
29978427
17.

Antiproliferative hydrogen sulfide releasing evodiamine derivatives and their apoptosis inducing properties.

Hu X, Jiao R, Li H, Wang X, Lyu H, Gao X, Xu F, Li Z, Hua H, Li D.

Eur J Med Chem. 2018 May 10;151:376-388. doi: 10.1016/j.ejmech.2018.04.009. Epub 2018 Apr 4.

PMID:
29635169
18.

Novel hybrids of brefeldin A and nitrogen mustards with improved antiproliferative selectivity: Design, synthesis and antitumor biological evaluation.

Han T, Tian K, Pan H, Liu Y, Xu F, Li Z, Uchita T, Gao M, Hua H, Li D.

Eur J Med Chem. 2018 Apr 25;150:53-63. doi: 10.1016/j.ejmech.2018.02.088. Epub 2018 Mar 1.

PMID:
29524728
19.

Novel enmein-type diterpenoid hybrids coupled with nitrogen mustards: Synthesis of promising candidates for anticancer therapeutics.

Gao X, Li J, Wang M, Xu S, Liu W, Zang L, Li Z, Hua H, Xu J, Li D.

Eur J Med Chem. 2018 Feb 25;146:588-598. doi: 10.1016/j.ejmech.2018.01.069. Epub 2018 Feb 4.

PMID:
29407983
20.

Polysaccharides from Trichosanthes Fructus via Ultrasound-Assisted Enzymatic Extraction Using Response Surface Methodology.

Chen F, Li D, Shen H, Wang C, Li E, Xing H, Guo L, Zhao Q, Shi J, Nguyen H, Liu J.

Biomed Res Int. 2017;2017:6160785. doi: 10.1155/2017/6160785. Epub 2017 Sep 25.

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