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Items: 1 to 20 of 29


Reactive carbonyl compounds impair wound healing by vimentin collapse and loss of the primary cilium.

Rodríguez-Ribera L, Slattery C, Mc Morrow T, Marcos R, Pastor S.

Food Chem Toxicol. 2017 Oct;108(Pt A):128-138. doi: 10.1016/j.fct.2017.07.055. Epub 2017 Jul 29.


Prolyl hydroxylase-1 regulates hepatocyte apoptosis in an NF-κB-dependent manner.

Fitzpatrick SF, Fábián Z, Schaible B, Lenihan CR, Schwarzl T, Rodriguez J, Zheng X, Li Z, Tambuwala MM, Higgins DG, O'Meara Y, Slattery C, Manresa MC, Fraisl P, Bruning U, Baes M, Carmeliet P, Doherty G, von Kriegsheim A, Cummins EP, Taylor CT.

Biochem Biophys Res Commun. 2016 Jun 3;474(3):579-586. doi: 10.1016/j.bbrc.2016.04.085. Epub 2016 Apr 27.


Tacrolimus Modulates TGF-β Signaling to Induce Epithelial-Mesenchymal Transition in Human Renal Proximal Tubule Epithelial Cells.

Bennett J, Cassidy H, Slattery C, Ryan MP, McMorrow T.

J Clin Med. 2016 Apr 26;5(5). pii: E50. doi: 10.3390/jcm5050050.


Cystine accumulation attenuates insulin release from the pancreatic β-cell due to elevated oxidative stress and decreased ATP levels.

McEvoy B, Sumayao R, Slattery C, McMorrow T, Newsholme P.

J Physiol. 2015 Dec 1;593(23):5167-82. doi: 10.1113/JP271237. Epub 2015 Nov 18.


New developments concerning the proximal tubule in diabetic nephropathy: in vitro models and mechanisms.

Slyne J, Slattery C, McMorrow T, Ryan MP.

Nephrol Dial Transplant. 2015 Aug;30 Suppl 4:iv60-7. doi: 10.1093/ndt/gfv264. Review.


Urinary biomarkers of chronic allograft nephropathy.

Cassidy H, Slyne J, O'Kelly P, Traynor C, Conlon PJ, Johnston O, Slattery C, Ryan MP, McMorrow T.

Proteomics Clin Appl. 2015 Jun;9(5-6):574-85. doi: 10.1002/prca.201400200.


Chloride channel ClC-5 binds to aspartyl aminopeptidase to regulate renal albumin endocytosis.

Lee A, Slattery C, Nikolic-Paterson DJ, Hryciw DH, Wilk S, Wilk E, Zhang Y, Valova VA, Robinson PJ, Kelly DJ, Poronnik P.

Am J Physiol Renal Physiol. 2015 Apr 1;308(7):F784-92. doi: 10.1152/ajprenal.00322.2014. Epub 2015 Jan 13.


Mechanisms of chemical carcinogenesis in the kidneys.

Radford R, Frain H, Ryan MP, Slattery C, McMorrow T.

Int J Mol Sci. 2013 Sep 25;14(10):19416-33. doi: 10.3390/ijms141019416. Review.


High-Throughput Proteomic Approaches to the Elucidation of Potential Biomarkers of Chronic Allograft Injury (CAI).

Cassidy H, Slyne J, Frain H, Slattery C, Ryan MP, McMorrow T.

Proteomes. 2013 Sep 23;1(2):159-179. doi: 10.3390/proteomes1020159. Review.


Sgk-1 is a positive regulator of constitutive albumin uptake in renal proximal tubule cells.

Hryciw DH, Kruger WA, Briffa JF, Slattery C, Bolithon A, Lee A, Poronnik P.

Cell Physiol Biochem. 2012;30(5):1215-26. doi: 10.1159/000343313. Epub 2012 Oct 15.


Oxidative stress induced by potassium bromate exposure results in altered tight junction protein expression in renal proximal tubule cells.

Limonciel A, Wilmes A, Aschauer L, Radford R, Bloch KM, McMorrow T, Pfaller W, van Delft JH, Slattery C, Ryan MP, Lock EA, Jennings P.

Arch Toxicol. 2012 Nov;86(11):1741-51. doi: 10.1007/s00204-012-0897-0. Epub 2012 Jul 4.


The role of MAPK in drug-induced kidney injury.

Cassidy H, Radford R, Slyne J, O'Connell S, Slattery C, Ryan MP, McMorrow T.

J Signal Transduct. 2012;2012:463617. doi: 10.1155/2012/463617. Epub 2012 Mar 12.


Sirolimus enhances cyclosporine a-induced cytotoxicity in human renal glomerular mesangial cells.

O'Connell S, Slattery C, Ryan MP, McMorrow T.

J Transplant. 2012;2012:980910. doi: 10.1155/2012/980910. Epub 2012 Jan 23.


Carcinogens induce loss of the primary cilium in human renal proximal tubular epithelial cells independently of effects on the cell cycle.

Radford R, Slattery C, Jennings P, Blacque O, Pfaller W, Gmuender H, Van Delft J, Ryan MP, McMorrow T.

Am J Physiol Renal Physiol. 2012 Apr 15;302(8):F905-16. doi: 10.1152/ajprenal.00427.2011. Epub 2012 Jan 18. Erratum in: Am J Physiol Renal Physiol. 2013 Sep 1;305(5):F796. Blaque, Oliver [corrected to Blacque, Oliver].


Cyclosporine A--induced oxidative stress in human renal mesangial cells: a role for ERK 1/2 MAPK signaling.

O'Connell S, Tuite N, Slattery C, Ryan MP, McMorrow T.

Toxicol Sci. 2012 Mar;126(1):101-13. doi: 10.1093/toxsci/kfr330. Epub 2011 Dec 6.


Transcriptomic alterations induced by Ochratoxin A in rat and human renal proximal tubular in vitro models and comparison to a rat in vivo model.

Jennings P, Weiland C, Limonciel A, Bloch KM, Radford R, Aschauer L, McMorrow T, Wilmes A, Pfaller W, Ahr HJ, Slattery C, Lock EA, Ryan MP, Ellinger-Ziegelbauer H.

Arch Toxicol. 2012 Apr;86(4):571-89. doi: 10.1007/s00204-011-0780-4. Epub 2011 Nov 29.


TGF-β1 mediates sirolimus and cyclosporine A-induced alteration of barrier function in renal epithelial cells via a noncanonical ERK1/2 signaling pathway.

Martin-Martin N, Slattery C, McMorrow T, Ryan MP.

Am J Physiol Renal Physiol. 2011 Dec;301(6):F1281-92. doi: 10.1152/ajprenal.00188.2010. Epub 2011 Aug 31.


Identification of novel indicators of cyclosporine A nephrotoxicity in a CD-1 mouse model.

O'Connell S, Slattery C, Ryan MP, McMorrow T.

Toxicol Appl Pharmacol. 2011 Apr 15;252(2):201-10. doi: 10.1016/j.taap.2011.02.015. Epub 2011 Feb 23.


Na+-H+ exchanger regulatory factor 1 (NHERF1) PDZ scaffold binds an internal binding site in the scavenger receptor megalin.

Slattery C, Jenkin KA, Lee A, Simcocks AC, McAinch AJ, Poronnik P, Hryciw DH.

Cell Physiol Biochem. 2011;27(2):171-8. doi: 10.1159/000325219. Epub 2011 Feb 11.


Metabolic response to low-level toxicant exposure in a novel renal tubule epithelial cell system.

Ellis JK, Athersuch TJ, Cavill R, Radford R, Slattery C, Jennings P, McMorrow T, Ryan MP, Ebbels TM, Keun HC.

Mol Biosyst. 2011 Jan;7(1):247-57. doi: 10.1039/c0mb00146e. Epub 2010 Nov 19.


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