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Items: 20

1.

Acid sphingomyelinase - a regulator of canonical transient receptor potential channel 6 (TRPC6) activity.

Zeitler S, Ye L, Andreyeva A, Schumacher F, Monti J, Nürnberg B, Nowak G, Kleuser B, Reichel M, Fejtová A, Kornhuber J, Rhein C, Friedland K.

J Neurochem. 2019 Sep;150(6):678-690. doi: 10.1111/jnc.14823. Epub 2019 Aug 22.

PMID:
31310676
2.

Alpha-Synuclein RNA Expression is Increased in Major Depression.

Rotter A, Lenz B, Pitsch R, Richter-Schmidinger T, Kornhuber J, Rhein C.

Int J Mol Sci. 2019 Apr 25;20(8). pii: E2029. doi: 10.3390/ijms20082029.

3.

Immunoregulatory role of acid sphingomyelinase in allergic asthma.

Sopel N, Kölle J, Dumendiak S, Koch S, Reichel M, Rhein C, Kornhuber J, Finotto S.

Immunology. 2019 Apr;156(4):373-383. doi: 10.1111/imm.13035. Epub 2019 Jan 13.

4.

Chronic Psychosocial Stress in Mice Is Associated With Increased Acid Sphingomyelinase Activity in Liver and Serum and With Hepatic C16:0-Ceramide Accumulation.

Reichel M, Rhein C, Hofmann LM, Monti J, Japtok L, Langgartner D, Füchsl AM, Kleuser B, Gulbins E, Hellerbrand C, Reber SO, Kornhuber J.

Front Psychiatry. 2018 Oct 16;9:496. doi: 10.3389/fpsyt.2018.00496. eCollection 2018.

5.

FRET probes for measuring sphingolipid metabolizing enzyme activity.

Mohamed ZH, Rhein C, Saied EM, Kornhuber J, Arenz C.

Chem Phys Lipids. 2018 Nov;216:152-161. doi: 10.1016/j.chemphyslip.2018.09.014. Epub 2018 Sep 24. Review.

PMID:
30261173
6.

Derivatization of common antidepressant drugs increases inhibition of acid sphingomyelinase and reduces induction of phospholipidosis.

Rhein C, Löber S, Gmeiner P, Gulbins E, Tripal P, Kornhuber J.

J Neural Transm (Vienna). 2018 Dec;125(12):1837-1845. doi: 10.1007/s00702-018-1923-z. Epub 2018 Sep 6.

PMID:
30191367
7.

Identification of an acid sphingomyelinase ceramide kinase pathway in the regulation of the chemokine CCL5.

Newcomb B, Rhein C, Mileva I, Ahmad R, Clarke CJ, Snider J, Obeid LM, Hannun YA.

J Lipid Res. 2018 Jul;59(7):1219-1229. doi: 10.1194/jlr.M084202. Epub 2018 May 3.

8.

Alternative splicing of SMPD1 coding for acid sphingomyelinase in major depression.

Rhein C, Reichel M, Kramer M, Rotter A, Lenz B, Mühle C, Gulbins E, Kornhuber J.

J Affect Disord. 2017 Feb;209:10-15. doi: 10.1016/j.jad.2016.09.019. Epub 2016 Sep 28.

PMID:
27866044
9.

Additive sex-specific influence of common non-synonymous DISC1 variants on amygdala, basal ganglia, and white cortical surface area in healthy young adults.

Mühle C, Kreczi J, Rhein C, Richter-Schmidinger T, Alexopoulos P, Doerfler A, Lenz B, Kornhuber J.

Brain Struct Funct. 2017 Mar;222(2):881-894. doi: 10.1007/s00429-016-1253-6. Epub 2016 Jul 1.

PMID:
27369464
10.

Alleged Detrimental Mutations in the SMPD1 Gene in Patients with Niemann-Pick Disease.

Rhein C, Mühle C, Kornhuber J, Reichel M.

Int J Mol Sci. 2015 Jun 15;16(6):13649-52. doi: 10.3390/ijms160613649.

11.

Secretory sphingomyelinase in health and disease.

Kornhuber J, Rhein C, Müller CP, Mühle C.

Biol Chem. 2015 Jun;396(6-7):707-36. doi: 10.1515/hsz-2015-0109. Review.

12.

Brain membrane lipids in major depression and anxiety disorders.

Müller CP, Reichel M, Mühle C, Rhein C, Gulbins E, Kornhuber J.

Biochim Biophys Acta. 2015 Aug;1851(8):1052-65. doi: 10.1016/j.bbalip.2014.12.014. Epub 2014 Dec 24. Review.

13.

Secretion of acid Sphingomyelinase is affected by its polymorphic signal peptide.

Rhein C, Reichel M, Mühle C, Rotter A, Schwab SG, Kornhuber J.

Cell Physiol Biochem. 2014;34(4):1385-401. doi: 10.1159/000366345. Epub 2014 Oct 2.

14.

The common acid sphingomyelinase polymorphism p.G508R is associated with self-reported allergy.

Reichel M, Richter-Schmidinger T, Mühle C, Rhein C, Alexopoulos P, Schwab SG, Gulbins E, Kornhuber J.

Cell Physiol Biochem. 2014;34(1):82-91. doi: 10.1159/000362986. Epub 2014 Jun 16.

15.

Neuroanatomical correlates of intelligence in healthy young adults: the role of basal ganglia volume.

Rhein C, Mühle C, Richter-Schmidinger T, Alexopoulos P, Doerfler A, Kornhuber J.

PLoS One. 2014 Apr 3;9(4):e93623. doi: 10.1371/journal.pone.0093623. eCollection 2014.

16.

The Acid Sphingomyelinase Sequence Variant p.A487V Is Not Associated With Decreased Levels of Enzymatic Activity.

Rhein C, Naumann J, Mühle C, Zill P, Adli M, Hegerl U, Hiemke C, Mergl R, Möller HJ, Reichel M, Kornhuber J.

JIMD Rep. 2013;8:1-6. doi: 10.1007/8904_2012_147. Epub 2012 May 26.

17.

Functional implications of novel human acid sphingomyelinase splice variants.

Rhein C, Tripal P, Seebahn A, Konrad A, Kramer M, Nagel C, Kemper J, Bode J, Mühle C, Gulbins E, Reichel M, Becker CM, Kornhuber J.

PLoS One. 2012;7(4):e35467. doi: 10.1371/journal.pone.0035467. Epub 2012 Apr 27.

18.

Hippocampal volume differences between healthy young apolipoprotein E ε2 and ε4 carriers.

Alexopoulos P, Richter-Schmidinger T, Horn M, Maus S, Reichel M, Sidiropoulos C, Rhein C, Lewczuk P, Doerfler A, Kornhuber J.

J Alzheimers Dis. 2011;26(2):207-10. doi: 10.3233/JAD-2011-110356.

PMID:
21606569
19.

Influence of brain-derived neurotrophic-factor and apolipoprotein E genetic variants on hippocampal volume and memory performance in healthy young adults.

Richter-Schmidinger T, Alexopoulos P, Horn M, Maus S, Reichel M, Rhein C, Lewczuk P, Sidiropoulos C, Kneib T, Perneczky R, Doerfler A, Kornhuber J.

J Neural Transm (Vienna). 2011 Feb;118(2):249-57. doi: 10.1007/s00702-010-0539-8. Epub 2010 Dec 29.

PMID:
21190051
20.

Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications.

Kornhuber J, Tripal P, Reichel M, Mühle C, Rhein C, Muehlbacher M, Groemer TW, Gulbins E.

Cell Physiol Biochem. 2010;26(1):9-20. doi: 10.1159/000315101. Epub 2010 May 18. Review.

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