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Items: 1 to 20 of 115

1.

Hypoxia and Innate Immunity: Keeping Up with the HIFsters.

Colgan SP, Furuta GT, Taylor CT.

Annu Rev Immunol. 2020 Jan 21. doi: 10.1146/annurev-immunol-100819-121537. [Epub ahead of print]

PMID:
31961750
2.

Mucosal inflammation downregulates PHD1 expression promoting a barrier-protective HIF-1α response in ulcerative colitis patients.

Brown E, Rowan C, Strowitzki MJ, Fagundes RR, Faber KN, Güntsch A, Halligan DN, Kugler J, Jones F, Lee CT, Doherty G, Taylor CT.

FASEB J. 2020 Jan 16. doi: 10.1096/fj.201902103R. [Epub ahead of print]

PMID:
31944416
3.

The Shc protein Rai enhances T-cell survival under hypoxia.

Criscuoli M, Ulivieri C, Filippi I, Monaci S, Guerrini G, Crifò B, De Tommaso D, Pelicci G, Baldari CT, Taylor CT, Carraro F, Naldini A.

J Cell Physiol. 2020 Jan 15. doi: 10.1002/jcp.29461. [Epub ahead of print]

PMID:
31944299
4.

The putative bacterial oxygen sensor Pseudomonas prolyl hydroxylase (PPHD) suppresses antibiotic resistance and pathogenicity in Pseudomonas aeruginosa.

Schaible B, Crifo B, Schaffer K, Taylor CT.

J Biol Chem. 2020 Jan 31;295(5):1195-1201. doi: 10.1074/jbc.RA119.010033. Epub 2019 Dec 11.

PMID:
31826919
5.

Prolyl Hydroxylase Inhibition Mitigates Pouchitis.

Harnoss JM, Gebhardt JM, Radhakrishnan P, Leowardi C, Burmeister J, Halligan DN, Yuan S, Kennel KB, Strowitzki MJ, Schaible A, Lasitschka F, Taylor CT, Schneider M.

Inflamm Bowel Dis. 2020 Jan 6;26(2):192-205. doi: 10.1093/ibd/izz218.

PMID:
31618435
6.

Mechanisms and Consequences of Oxygen and Carbon Dioxide Sensing in Mammals.

Cummins EP, Strowitzki MJ, Taylor CT.

Physiol Rev. 2020 Jan 1;100(1):463-488. doi: 10.1152/physrev.00003.2019. Epub 2019 Sep 20.

PMID:
31539306
7.

Hypoxia-inducible factor hydroxylase inhibition enhances the protective effects of cyclosporine in colitis.

Halligan DN, Khan MN, Brown E, Rowan CR, Coulter IS, Doherty GA, Tambuwala MM, Taylor CT.

Am J Physiol Gastrointest Liver Physiol. 2019 Aug 1;317(2):G90-G97. doi: 10.1152/ajpgi.00049.2019. Epub 2019 May 9.

PMID:
31070931
8.

Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?

Strowitzki MJ, Cummins EP, Taylor CT.

Cells. 2019 Apr 26;8(5). pii: E384. doi: 10.3390/cells8050384. Review.

9.

Hydroxylase Inhibition Selectively Induces Cell Death in Monocytes.

Crifo B, Schaible B, Brown E, Halligan DN, Scholz CC, Fitzpatrick SF, Kirwan A, Roche HM, Criscuoli M, Naldini A, Giffney H, Crean D, Blanco A, Cavadas MA, Cummins EP, Fabian Z, Taylor CT.

J Immunol. 2019 Mar 1;202(5):1521-1530. doi: 10.4049/jimmunol.1800912. Epub 2019 Jan 30.

PMID:
30700584
10.

Increased Virulence of Bloodstream Over Peripheral Isolates of P. aeruginosa Identified Through Post-transcriptional Regulation of Virulence Factors.

Hickey C, Schaible B, Nguyen S, Hurley D, Srikumar S, Fanning S, Brown E, Crifo B, Matallanas D, McClean S, Taylor CT, Schaffer K.

Front Cell Infect Microbiol. 2018 Oct 26;8:357. doi: 10.3389/fcimb.2018.00357. eCollection 2018.

11.

Pharmacologic inhibition of hypoxia-inducible factor (HIF)-hydroxylases ameliorates allergic contact dermatitis.

Manresa MC, Smith L, Casals-Diaz L, Fagundes RR, Brown E, Radhakrishnan P, Murphy SJ, Crifo B, Strowitzki MJ, Halligan DN, van den Bogaard EH, Niehues H, Schneider M, Taylor CT, Steinhoff M.

Allergy. 2019 Apr;74(4):753-766. doi: 10.1111/all.13655. Epub 2018 Dec 12.

PMID:
30394557
12.

The PHD1 oxygen sensor in health and disease.

Kennel KB, Burmeister J, Schneider M, Taylor CT.

J Physiol. 2018 Sep;596(17):3899-3913. doi: 10.1113/JP275327. Epub 2018 Mar 5. Review.

13.

Acquisition of Temporal HIF Transcriptional Activity Using a Secreted Luciferase Assay.

Cavadas MAS, Taylor CT, Cheong A.

Methods Mol Biol. 2018;1742:37-44. doi: 10.1007/978-1-4939-7665-2_4.

PMID:
29330788
14.

Genetic Knockdown and Pharmacologic Inhibition of Hypoxia-Inducible Factor (HIF) Hydroxylases.

Pickel C, Taylor CT, Scholz CC.

Methods Mol Biol. 2018;1742:1-14. doi: 10.1007/978-1-4939-7665-2_1.

PMID:
29330785
15.

Hypoxia in the Gut.

Taylor CT.

Cell Mol Gastroenterol Hepatol. 2017 Sep 19;5(1):61-62. doi: 10.1016/j.jcmgh.2017.09.005. eCollection 2018. No abstract available.

16.

Hypoxia-sensitive pathways in intestinal inflammation.

Brown E, Taylor CT.

J Physiol. 2018 Aug;596(15):2985-2989. doi: 10.1113/JP274350. Epub 2017 Nov 28. Review.

17.

Regulation of immunity and inflammation by hypoxia in immunological niches.

Taylor CT, Colgan SP.

Nat Rev Immunol. 2017 Dec;17(12):774-785. doi: 10.1038/nri.2017.103. Epub 2017 Oct 3. Review.

18.

Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses.

Sadiku P, Willson JA, Dickinson RS, Murphy F, Harris AJ, Lewis A, Sammut D, Mirchandani AS, Ryan E, Watts ER, Thompson AAR, Marriott HM, Dockrell DH, Taylor CT, Schneider M, Maxwell PH, Chilvers ER, Mazzone M, Moral V, Pugh CW, Ratcliffe PJ, Schofield CJ, Ghesquiere B, Carmeliet P, Whyte MK, Walmsley SR.

J Clin Invest. 2017 Sep 1;127(9):3407-3420. doi: 10.1172/JCI90848. Epub 2017 Aug 14.

19.

Hypoxia Inducible Factor (HIF) Hydroxylases as Regulators of Intestinal Epithelial Barrier Function.

Manresa MC, Taylor CT.

Cell Mol Gastroenterol Hepatol. 2017 Feb 20;3(3):303-315. doi: 10.1016/j.jcmgh.2017.02.004. eCollection 2017 May. Review.

20.

Determinants of hypoxia-inducible factor activity in the intestinal mucosa.

Fagundes RR, Taylor CT.

J Appl Physiol (1985). 2017 Nov 1;123(5):1328-1334. doi: 10.1152/japplphysiol.00203.2017. Epub 2017 Apr 13. Review.

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