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Items: 19

1.

Efficient CRISPR/Cas9 Gene Editing in Uncultured Naive Mouse T Cells for In Vivo Studies.

Nüssing S, House IG, Kearney CJ, Chen AXY, Vervoort SJ, Beavis PA, Oliaro J, Johnstone RW, Trapani JA, Parish IA.

J Immunol. 2020 Mar 9. pii: ji1901396. doi: 10.4049/jimmunol.1901396. [Epub ahead of print]

PMID:
32152070
2.

The Immuno-Modulatory Effects of Inhibitor of Apoptosis Protein Antagonists in Cancer Immunotherapy.

Michie J, Kearney CJ, Hawkins ED, Silke J, Oliaro J.

Cells. 2020 Jan 14;9(1). pii: E207. doi: 10.3390/cells9010207. Review.

3.

Natural Killer Cells Suppress T Cell-Associated Tumor Immune Evasion.

Freeman AJ, Vervoort SJ, Ramsbottom KM, Kelly MJ, Michie J, Pijpers L, Johnstone RW, Kearney CJ, Oliaro J.

Cell Rep. 2019 Sep 10;28(11):2784-2794.e5. doi: 10.1016/j.celrep.2019.08.017.

4.

Protection from EAE in DOCK8 mutant mice occurs despite increased Th17 cell frequencies in the periphery.

Wilson AS, Law HD, Knobbe-Thomsen CB, Kearney CJ, Oliaro J, Binsfeld C, Burgio G, Starrs L, Brenner D, Randall KL, Brüstle A.

Eur J Immunol. 2019 May;49(5):770-781. doi: 10.1002/eji.201847960. Epub 2019 Feb 20.

PMID:
30729501
5.

Antagonism of IAPs Enhances CAR T-cell Efficacy.

Michie J, Beavis PA, Freeman AJ, Vervoort SJ, Ramsbottom KM, Narasimhan V, Lelliott EJ, Lalaoui N, Ramsay RG, Johnstone RW, Silke J, Darcy PK, Voskoboinik I, Kearney CJ, Oliaro J.

Cancer Immunol Res. 2019 Feb;7(2):183-192. doi: 10.1158/2326-6066.CIR-18-0428. Epub 2019 Jan 16.

6.

Tumor immune evasion arises through loss of TNF sensitivity.

Kearney CJ, Vervoort SJ, Hogg SJ, Ramsbottom KM, Freeman AJ, Lalaoui N, Pijpers L, Michie J, Brown KK, Knight DA, Sutton V, Beavis PA, Voskoboinik I, Darcy PK, Silke J, Trapani JA, Johnstone RW, Oliaro J.

Sci Immunol. 2018 May 18;3(23). pii: eaar3451. doi: 10.1126/sciimmunol.aar3451.

PMID:
29776993
7.

Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1's Cytotoxic Potential.

Feltham R, Jamal K, Tenev T, Liccardi G, Jaco I, Domingues CM, Morris O, John SW, Annibaldi A, Widya M, Kearney CJ, Clancy D, Elliott PR, Glatter T, Qiao Q, Thompson AJ, Nesvizhskii A, Schmidt A, Komander D, Wu H, Martin S, Meier P.

Cell Rep. 2018 Apr 10;23(2):470-484. doi: 10.1016/j.celrep.2018.03.054.

8.

DOCK8 Drives Src-Dependent NK Cell Effector Function.

Kearney CJ, Vervoort SJ, Ramsbottom KM, Freeman AJ, Michie J, Peake J, Casanova JL, Picard C, Tangye SG, Ma CS, Johnstone RW, Randall KL, Oliaro J.

J Immunol. 2017 Aug 9. pii: ji1700751. doi: 10.4049/jimmunol.1700751. [Epub ahead of print]

PMID:
28794229
9.

PD-L1 and IAPs co-operate to protect tumors from cytotoxic lymphocyte-derived TNF.

Kearney CJ, Lalaoui N, Freeman AJ, Ramsbottom KM, Silke J, Oliaro J.

Cell Death Differ. 2017 Oct;24(10):1705-1716. doi: 10.1038/cdd.2017.94. Epub 2017 Jun 30.

10.

DOCK8 regulates signal transduction events to control immunity.

Kearney CJ, Randall KL, Oliaro J.

Cell Mol Immunol. 2017 May;14(5):406-411. doi: 10.1038/cmi.2017.9. Epub 2017 Apr 3. Review.

11.

An Inflammatory Perspective on Necroptosis.

Kearney CJ, Martin SJ.

Mol Cell. 2017 Mar 16;65(6):965-973. doi: 10.1016/j.molcel.2017.02.024. Review.

12.

Loss of DNAM-1 ligand expression by acute myeloid leukemia cells renders them resistant to NK cell killing.

Kearney CJ, Ramsbottom KM, Voskoboinik I, Darcy PK, Oliaro J.

Oncoimmunology. 2016 Jun 27;5(8):e1196308. doi: 10.1080/2162402X.2016.1196308. eCollection 2016 Aug.

13.

The Role of the immunological Synapse Formed by Cytotoxic Lymphocytes in Immunodeficiency and Anti-Tumor immunity.

Kearney CJ, Brennan AJ, Darcy PK, Oliaro J.

Crit Rev Immunol. 2015;35(4):325-47. Review.

PMID:
26757394
14.

A chromatin-independent role of Polycomb-like 1 to stabilize p53 and promote cellular quiescence.

Brien GL, Healy E, Jerman E, Conway E, Fadda E, O'Donovan D, Krivtsov AV, Rice AM, Kearney CJ, Flaus A, McDade SS, Martin SJ, McLysaght A, O'Connell DJ, Armstrong SA, Bracken AP.

Genes Dev. 2015 Nov 1;29(21):2231-43. doi: 10.1101/gad.267930.115. Epub 2015 Oct 22.

15.

Diverse Activators of the NLRP3 Inflammasome Promote IL-1β Secretion by Triggering Necrosis.

Cullen SP, Kearney CJ, Clancy DM, Martin SJ.

Cell Rep. 2015 Jun 16;11(10):1535-48. doi: 10.1016/j.celrep.2015.05.003. Epub 2015 May 28.

16.

RIPK1 can function as an inhibitor rather than an initiator of RIPK3-dependent necroptosis.

Kearney CJ, Cullen SP, Clancy D, Martin SJ.

FEBS J. 2014 Nov;281(21):4921-34. doi: 10.1111/febs.13034. Epub 2014 Oct 4.

17.

Inflammatory outcomes of apoptosis, necrosis and necroptosis.

Davidovich P, Kearney CJ, Martin SJ.

Biol Chem. 2014 Oct;395(10):1163-71. doi: 10.1515/hsz-2014-0164. Review.

PMID:
25153241
18.

Fas/CD95-induced chemokines can serve as "find-me" signals for apoptotic cells.

Cullen SP, Henry CM, Kearney CJ, Logue SE, Feoktistova M, Tynan GA, Lavelle EC, Leverkus M, Martin SJ.

Mol Cell. 2013 Mar 28;49(6):1034-48. doi: 10.1016/j.molcel.2013.01.025. Epub 2013 Feb 21.

19.

Inhibitor of apoptosis proteins (IAPs) and their antagonists regulate spontaneous and tumor necrosis factor (TNF)-induced proinflammatory cytokine and chemokine production.

Kearney CJ, Sheridan C, Cullen SP, Tynan GA, Logue SE, Afonina IS, Vucic D, Lavelle EC, Martin SJ.

J Biol Chem. 2013 Feb 15;288(7):4878-90. doi: 10.1074/jbc.M112.422410. Epub 2012 Dec 28.

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