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Items: 1 to 20 of 54


Flavonolignans: One Step Further in the Broad-Spectrum Approach of Cancer.

Antal DS, Ardelean F, Avram S, Pavel IZ, Danciu C, Soica C, Dehelean C.

Anticancer Agents Med Chem. 2020 Jan 23. doi: 10.2174/1871520620666200124112649. [Epub ahead of print]


Development of Nanoparticulate Formulations with Biomedical Applications Related to Cancer.

Soica CM.

Curr Med Chem. 2019;26(35):6438-6439. doi: 10.2174/092986732635191112162427. No abstract available.


Cannabidiol-from Plant to Human Body: A Promising Bioactive Molecule with Multi-Target Effects in Cancer.

Kis B, Ifrim FC, Buda V, Avram S, Pavel IZ, Antal D, Paunescu V, Dehelean CA, Ardelean F, Diaconeasa Z, Soica C, Danciu C.

Int J Mol Sci. 2019 Nov 25;20(23). pii: E5905. doi: 10.3390/ijms20235905. Review.


Fe3O4@C Matrix with Tailorable Adsorption Capacities for Paracetamol and Acetylsalicylic Acid: Synthesis, Characterization, and Kinetic Modeling.

Moacă EA, Mihali CV, Macaşoi IG, Racoviceanu Băbuţă R, Şoica C, Dehelean CA, Păcurariu C, Florescu S.

Molecules. 2019 May 3;24(9). pii: E1727. doi: 10.3390/molecules24091727.


Gold Nanoparticles as Targeted Delivery Systems and Theranostic Agents in Cancer Therapy.

Mioc A, Mioc M, Ghiulai R, Voicu M, Racoviceanu R, Trandafirescu C, Dehelean C, Coricovac D, Soica C.

Curr Med Chem. 2019;26(35):6493-6513. doi: 10.2174/0929867326666190506123721. Review.


A Comprehensive Assessment of Apigenin as an Antiproliferative, Proapoptotic, Antiangiogenic and Immunomodulatory Phytocompound.

Ghițu A, Schwiebs A, Radeke HH, Avram S, Zupko I, Bor A, Pavel IZ, Dehelean CA, Oprean C, Bojin F, Farcas C, Soica C, Duicu O, Danciu C.

Nutrients. 2019 Apr 16;11(4). pii: E858. doi: 10.3390/nu11040858.


Cocrystal Formation of Betulinic Acid and Ascorbic Acid: Synthesis, Physico-Chemical Assessment, Antioxidant, and Antiproliferative Activity.

Nicolov M, Ghiulai RM, Voicu M, Mioc M, Duse AO, Roman R, Ambrus R, Zupko I, Moaca EA, Coricovac DE, Farcas C, Racoviceanu RM, Danciu C, Dehelean CA, Soica C.

Front Chem. 2019 Feb 21;7:92. doi: 10.3389/fchem.2019.00092. eCollection 2019.


Phytochemical Characterization and Evaluation of the Antimicrobial, Antiproliferative and Pro-Apoptotic Potential of Ephedra alata Decne. Hydroalcoholic Extract against the MCF-7 Breast Cancer Cell Line.

Danciu C, Muntean D, Alexa E, Farcas C, Oprean C, Zupko I, Bor A, Minda D, Proks M, Buda V, Hancianu M, Cioanca O, Soica C, Popescu S, Dehelean CA.

Molecules. 2018 Dec 20;24(1). pii: E13. doi: 10.3390/molecules24010013.


Botanical Therapeutics: Phytochemical Screening and Biological Assessment of Chamomile, Parsley and Celery Extracts against A375 Human Melanoma and Dendritic Cells.

Danciu C, Zupko I, Bor A, Schwiebs A, Radeke H, Hancianu M, Cioanca O, Alexa E, Oprean C, Bojin F, Soica C, Paunescu V, Dehelean CA.

Int J Mol Sci. 2018 Nov 16;19(11). pii: E3624. doi: 10.3390/ijms19113624.


Ethinylestradiol and Levonorgestrel as Active Agents in Normal Skin, and Pathological Conditions Induced by UVB Exposure: In Vitro and In Ovo Assessments.

Coricovac D, Farcas C, Nica C, Pinzaru I, Simu S, Stoian D, Soica C, Proks M, Avram S, Navolan D, Dumitru C, Popovici RA, Dehelean CA.

Int J Mol Sci. 2018 Nov 14;19(11). pii: E3600. doi: 10.3390/ijms19113600.


Betulin silver nanoparticles qualify as efficient antimelanoma agents in in vitro and in vivo studies.

Danciu C, Pinzaru I, Coricovac D, Andrica F, Sizemore I, Dehelean C, Baderca F, Lazureanu V, Soica C, Mioc M, Radeke H.

Eur J Pharm Biopharm. 2019 Jan;134:1-19. doi: 10.1016/j.ejpb.2018.11.006. Epub 2018 Nov 7.


Pharmaceutical Mixtures: Still A Concern For Human And Environmental Health.

Simu GM, Atchana J, Soica CM, Coricovac DE, Simu SC, Dehelean CA.

Curr Med Chem. 2018 Nov 7. doi: 10.2174/0929867325666181108094222. [Epub ahead of print]


Design, Synthesis and Biological Activity Evaluation of S-Substituted 1H-5-Mercapto-1,2,4-Triazole Derivatives as Antiproliferative Agents in Colorectal Cancer.

Mioc M, Avram S, Bercean V, Kurunczi L, Ghiulai RM, Oprean C, Coricovac DE, Dehelean C, Mioc A, Balan-Porcarasu M, Tatu C, Soica C.

Front Chem. 2018 Aug 23;6:373. doi: 10.3389/fchem.2018.00373. eCollection 2018.


The Cytotoxic Effects of Betulin-Conjugated Gold Nanoparticles as Stable Formulations in Normal and Melanoma Cells.

Mioc M, Pavel IZ, Ghiulai R, Coricovac DE, Farcaş C, Mihali CV, Oprean C, Serafim V, Popovici RA, Dehelean CA, Shtilman MI, Tsatsakis AM, Şoica C.

Front Pharmacol. 2018 May 3;9:429. doi: 10.3389/fphar.2018.00429. eCollection 2018.


Rutin and Its Cyclodextrin Inclusion Complexes: Physico-chemical Evaluation and in vitro Activity on B164A5 Murine Melanoma Cell Line.

Corina D, Florina B, Iulia P, Cristina D, Rita A, Alexandra P, Virgil P, Hancianu M, Daliana M, Codruta S.

Curr Pharm Biotechnol. 2017;18(13):1067-1077. doi: 10.2174/1389201019666180209165523.


Total phenolic content, FTIR analysis, and antiproliferative evaluation of lupin seeds harvest from western Romania.

Danciu C, Pavel IZ, Babuta R, Ersilia A, Pop G, Soica C, Dehelean C, Radulov I, Oana S.

Ann Agric Environ Med. 2017 Dec 23;24(4):726-731. doi: 10.26444/aaem/80795. Epub 2017 Dec 22.


Stable PEG-coated silver nanoparticles - A comprehensive toxicological profile.

Pinzaru I, Coricovac D, Dehelean C, Moacă EA, Mioc M, Baderca F, Sizemore I, Brittle S, Marti D, Calina CD, Tsatsakis AM, Şoica C.

Food Chem Toxicol. 2018 Jan;111:546-556. doi: 10.1016/j.fct.2017.11.051. Epub 2017 Dec 2.


Natural Compounds in the Chemoprevention of Malignant Melanoma.

Danciu C, Soica C, Antal D, Alexa E, Pavel IZ, Ghiulai R, Ardelean F, Babuta RM, Popescu A, Dehelean CA.

Anticancer Agents Med Chem. 2018;18(5):631-644. doi: 10.2174/1871520617666171121142522. Review.


Main Isoflavones Found in Dietary Sources as Natural Anti-inflammatory Agents.

Danciu C, Avram S, Pavel IZ, Ghiulai R, Dehelean CA, Ersilia A, Minda D, Petrescu C, Moaca EA, Soica C.

Curr Drug Targets. 2018;19(7):841-853. doi: 10.2174/1389450118666171109150731. Review.


Effects of ursolic and oleanolic on SK‑MEL‑2 melanoma cells: In vitro and in vivo assays.

Caunii A, Oprean C, Cristea M, Ivan A, Danciu C, Tatu C, Paunescu V, Marti D, Tzanakakis G, Spandidos DA, Tsatsakis A, Susan R, Soica C, Avram S, Dehelean C.

Int J Oncol. 2017 Dec;51(6):1651-1660. doi: 10.3892/ijo.2017.4160. Epub 2017 Oct 16.

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