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Items: 16

1.

Global Proteome of LonP1+/- Mouse Embryonal Fibroblasts Reveals Impact on Respiratory Chain, but No Interdependence between Eral1 and Mitoribosomes.

Key J, Kohli A, Bárcena C, López-Otín C, Heidler J, Wittig I, Auburger G.

Int J Mol Sci. 2019 Sep 12;20(18). pii: E4523. doi: 10.3390/ijms20184523.

2.

Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice.

Bárcena C, Valdés-Mas R, Mayoral P, Garabaya C, Durand S, Rodríguez F, Fernández-García MT, Salazar N, Nogacka AM, Garatachea N, Bossut N, Aprahamian F, Lucia A, Kroemer G, Freije JMP, Quirós PM, López-Otín C.

Nat Med. 2019 Aug;25(8):1234-1242. doi: 10.1038/s41591-019-0504-5. Epub 2019 Jul 22.

PMID:
31332389
3.

Mitochondrial LonP1 protects cardiomyocytes from ischemia/reperfusion injury in vivo.

Venkatesh S, Li M, Saito T, Tong M, Rashed E, Mareedu S, Zhai P, Bárcena C, López-Otín C, Yehia G, Sadoshima J, Suzuki CK.

J Mol Cell Cardiol. 2019 Mar;128:38-50. doi: 10.1016/j.yjmcc.2018.12.017. Epub 2019 Jan 6.

PMID:
30625302
4.

Methionine restriction for improving progeria: another autophagy-inducing anti-aging strategy?

Bárcena C, López-Otín C, Kroemer G.

Autophagy. 2019 Mar;15(3):558-559. doi: 10.1080/15548627.2018.1533059. Epub 2018 Oct 18.

5.

Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism.

Bárcena C, Quirós PM, Durand S, Mayoral P, Rodríguez F, Caravia XM, Mariño G, Garabaya C, Fernández-García MT, Kroemer G, Freije JMP, López-Otín C.

Cell Rep. 2018 Aug 28;24(9):2392-2403. doi: 10.1016/j.celrep.2018.07.089.

6.

Mitohormesis, an Antiaging Paradigm.

Bárcena C, Mayoral P, Quirós PM.

Int Rev Cell Mol Biol. 2018;340:35-77. doi: 10.1016/bs.ircmb.2018.05.002. Epub 2018 Jun 21. Review.

PMID:
30072093
7.

A fruitful liaison of ZSCAN10 and ROS on the road to rejuvenation.

Bárcena C, López-Otín C.

Nat Cell Biol. 2017 Aug 31;19(9):1012-1013. doi: 10.1038/ncb3602.

PMID:
28855729
8.

Autophagy couteracts weight gain, lipotoxicity and pancreatic β-cell death upon hypercaloric pro-diabetic regimens.

Fernández ÁF, Bárcena C, Martínez-García GG, Tamargo-Gómez I, Suárez MF, Pietrocola F, Castoldi F, Esteban L, Sierra-Filardi E, Boya P, López-Otín C, Kroemer G, Mariño G.

Cell Death Dis. 2017 Aug 3;8(8):e2970. doi: 10.1038/cddis.2017.373.

9.

Interruption of progerin-lamin A/C binding ameliorates Hutchinson-Gilford progeria syndrome phenotype.

Lee SJ, Jung YS, Yoon MH, Kang SM, Oh AY, Lee JH, Jun SY, Woo TG, Chun HY, Kim SK, Chung KJ, Lee HY, Lee K, Jin G, Na MK, Ha NC, Bárcena C, Freije JM, López-Otín C, Song GY, Park BJ.

J Clin Invest. 2016 Oct 3;126(10):3879-3893. doi: 10.1172/JCI84164. Epub 2016 Sep 12.

10.

Novel LMNA mutations cause an aggressive atypical neonatal progeria without progerin accumulation.

Soria-Valles C, Carrero D, Gabau E, Velasco G, Quesada V, Bárcena C, Moens M, Fieggen K, Möhrcken S, Owens M, Puente DA, Asensio Ó, Loeys B, Pérez A, Benoit V, Wuyts W, Lévy N, Hennekam RC, De Sandre-Giovannoli A, López-Otín C.

J Med Genet. 2016 Nov;53(11):776-785. doi: 10.1136/jmedgenet-2015-103695. Epub 2016 Jun 22.

PMID:
27334370
11.

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.

Konermann S, Brigham MD, Trevino AE, Joung J, Abudayyeh OO, Barcena C, Hsu PD, Habib N, Gootenberg JS, Nishimasu H, Nureki O, Zhang F.

Nature. 2015 Jan 29;517(7536):583-8. doi: 10.1038/nature14136. Epub 2014 Dec 10.

12.

Lon protease: A key enzyme controlling mitochondrial bioenergetics in cancer.

Quirós PM, Bárcena C, López-Otín C.

Mol Cell Oncol. 2014 Dec 31;1(4):e968505. doi: 10.4161/23723548.2014.968505. eCollection 2014 Oct-Dec.

13.

ATP-dependent Lon protease controls tumor bioenergetics by reprogramming mitochondrial activity.

Quirós PM, Español Y, Acín-Pérez R, Rodríguez F, Bárcena C, Watanabe K, Calvo E, Loureiro M, Fernández-García MS, Fueyo A, Vázquez J, Enríquez JA, López-Otín C.

Cell Rep. 2014 Jul 24;8(2):542-56. doi: 10.1016/j.celrep.2014.06.018. Epub 2014 Jul 10.

14.

Exome sequencing identifies a novel mutation in PIK3R1 as the cause of SHORT syndrome.

Bárcena C, Quesada V, De Sandre-Giovannoli A, Puente DA, Fernández-Toral J, Sigaudy S, Baban A, Lévy N, Velasco G, López-Otín C.

BMC Med Genet. 2014 May 2;15:51. doi: 10.1186/1471-2350-15-51.

15.

Detection of nuclear envelope alterations in senescence.

Bárcena C, Osorio FG, Freije JM.

Methods Mol Biol. 2013;965:243-51. doi: 10.1007/978-1-62703-239-1_16.

PMID:
23296663
16.

Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response.

Osorio FG, Bárcena C, Soria-Valles C, Ramsay AJ, de Carlos F, Cobo J, Fueyo A, Freije JM, López-Otín C.

Genes Dev. 2012 Oct 15;26(20):2311-24. doi: 10.1101/gad.197954.112. Epub 2012 Sep 26.

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