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Items: 1 to 20 of 169

1.

Publisher Correction: Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.

Carreras-Sureda A, Jaña F, Urra H, Durand S, Mortenson DE, Sagredo A, Bustos G, Hazari Y, Ramos-Fernández E, Sassano ML, Pihán P, van Vliet AR, González-Quiroz M, Torres AK, Tapia-Rojas C, Kerkhofs M, Vicente R, Kaufman RJ, Inestrosa NC, Gonzalez-Billault C, Wiseman RL, Agostinis P, Bultynck G, Court FA, Kroemer G, Cárdenas JC, Hetz C.

Nat Cell Biol. 2019 Jun 14. doi: 10.1038/s41556-019-0355-9. [Epub ahead of print]

PMID:
31201389
2.

β-catenin aggregation in models of ALS motor neurons: GSK3β inhibition effect and neuronal differentiation.

Pinto C, Medinas DB, Fuentes-Villalobos F, Maripillán J, Castro AF, Martínez AD, Osses N, Hetz C, Henríquez JP.

Neurobiol Dis. 2019 Jun 7;130:104497. doi: 10.1016/j.nbd.2019.104497. [Epub ahead of print]

PMID:
31176720
3.

Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.

Carreras-Sureda A, Jaña F, Urra H, Durand S, Mortenson DE, Sagredo A, Bustos G, Hazari Y, Ramos-Fernández E, Sassano ML, Pihán P, van Vliet AR, González-Quiroz M, Torres AK, Tapia-Rojas C, Kerkhofs M, Vicente R, Kaufman RJ, Inestrosa NC, Gonzalez-Billault C, Wiseman RL, Agostinis P, Bultynck G, Court FA, Kroemer G, Cárdenas JC, Hetz C.

Nat Cell Biol. 2019 Jun;21(6):755-767. doi: 10.1038/s41556-019-0329-y. Epub 2019 May 20. Erratum in: Nat Cell Biol. 2019 Jun 14;:.

PMID:
31110288
4.

Emerging Roles of the Endoplasmic Reticulum Associated Unfolded Protein Response in Cancer Cell Migration and Invasion.

Limia CM, Sauzay C, Urra H, Hetz C, Chevet E, Avril T.

Cancers (Basel). 2019 May 6;11(5). pii: E631. doi: 10.3390/cancers11050631. Review.

5.

Targeting of the unfolded protein response (UPR) as therapy for Parkinson's disease.

Martinez A, Lopez N, Gonzalez C, Hetz C.

Biol Cell. 2019 Jun;111(6):161-168. doi: 10.1111/boc.201800068. Epub 2019 Mar 25. Review.

PMID:
30860281
6.

Brain organoids: a next step for humanized Alzheimer's disease models?

Gerakis Y, Hetz C.

Mol Psychiatry. 2019 Apr;24(4):474-478. doi: 10.1038/s41380-018-0343-7. Epub 2019 Jan 7. No abstract available.

PMID:
30617271
7.

ER stress links aging to sporadic ALS.

Medinas DB, Cabral-Miranda F, Hetz C.

Aging (Albany NY). 2019 Jan 5;11(1):5-6. doi: 10.18632/aging.101705. No abstract available.

8.

Interplay Between the Unfolded Protein Response and Immune Function in the Development of Neurodegenerative Diseases.

García-González P, Cabral-Miranda F, Hetz C, Osorio F.

Front Immunol. 2018 Nov 2;9:2541. doi: 10.3389/fimmu.2018.02541. eCollection 2018. Review.

9.

Cyclosporine A binding to COX-2 reveals a novel signaling pathway that activates the IRE1α unfolded protein response sensor.

Groenendyk J, Paskevicius T, Urra H, Viricel C, Wang K, Barakat K, Hetz C, Kurgan L, Agellon LB, Michalak M.

Sci Rep. 2018 Nov 12;8(1):16678. doi: 10.1038/s41598-018-34891-w.

10.

Publisher Correction: IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A.

Urra H, Henriquez DR, Cánovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, Molina E, Hazari YM, Limia CM, Alvarez-Rojas S, Figueroa R, Vidal RL, Rodriguez DA, Rivera CA, Court FA, Couve A, Qi L, Chevet E, Akai R, Iwawaki T, Concha ML, Glavic Á, Gonzalez-Billault C, Hetz C.

Nat Cell Biol. 2018 Oct;20(10):1228. doi: 10.1038/s41556-018-0186-0.

PMID:
30089843
11.

Endoplasmic reticulum stress leads to accumulation of wild-type SOD1 aggregates associated with sporadic amyotrophic lateral sclerosis.

Medinas DB, Rozas P, Martínez Traub F, Woehlbier U, Brown RH, Bosco DA, Hetz C.

Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8209-8214. doi: 10.1073/pnas.1801109115. Epub 2018 Jul 23.

12.

A new model to study cell-to-cell transfer of αSynuclein in vivo.

Mercado G, López N, Martínez A, Sardi SP, Hetz C.

Biochem Biophys Res Commun. 2018 Sep 10;503(3):1385-1393. doi: 10.1016/j.bbrc.2018.07.053. Epub 2018 Jul 17.

PMID:
30025892
13.

IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A.

Urra H, Henriquez DR, Cánovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, Molina E, Hazari YM, Limia CM, Alvarez-Rojas S, Figueroa R, Vidal RL, Rodriguez DA, Rivera CA, Court FA, Couve A, Qi L, Chevet E, Akai R, Iwawaki T, Concha ML, Glavic Á, Gonzalez-Billault C, Hetz C.

Nat Cell Biol. 2018 Aug;20(8):942-953. doi: 10.1038/s41556-018-0141-0. Epub 2018 Jul 16. Erratum in: Nat Cell Biol. 2018 Oct;20(10):1228.

PMID:
30013108
14.

ER Proteostasis Control of Neuronal Physiology and Synaptic Function.

Martínez G, Khatiwada S, Costa-Mattioli M, Hetz C.

Trends Neurosci. 2018 Sep;41(9):610-624. doi: 10.1016/j.tins.2018.05.009. Epub 2018 Jun 23. Review.

PMID:
29945734
15.

Endoplasmic reticulum stress signalling and the pathogenesis of non-alcoholic fatty liver disease.

Lebeaupin C, Vallée D, Hazari Y, Hetz C, Chevet E, Bailly-Maitre B.

J Hepatol. 2018 Oct;69(4):927-947. doi: 10.1016/j.jhep.2018.06.008. Epub 2018 Jun 27. Review.

16.

ER stress sensing mechanism: Putting off the brake on UPR transducers.

Rojas-Rivera D, Rodriguez DA, Sepulveda D, Hetz C.

Oncotarget. 2018 Apr 13;9(28):19461-19462. doi: 10.18632/oncotarget.25114. eCollection 2018 Apr 13. No abstract available.

17.

Gene Therapy Strategies to Restore ER Proteostasis in Disease.

Valenzuela V, Jackson KL, Sardi SP, Hetz C.

Mol Ther. 2018 Jun 6;26(6):1404-1413. doi: 10.1016/j.ymthe.2018.04.004. Epub 2018 Apr 7. Review.

18.

Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral sclerosis.

Matamala JM, Arias-Carrasco R, Sanchez C, Uhrig M, Bargsted L, Matus S, Maracaja-Coutinho V, Abarzua S, van Zundert B, Verdugo R, Manque P, Hetz C.

Neurobiol Aging. 2018 Apr;64:123-138. doi: 10.1016/j.neurobiolaging.2017.12.020. Epub 2017 Dec 29.

PMID:
29458840
19.

Unraveling the role of motoneuron autophagy in ALS.

Valenzuela V, Nassif M, Hetz C.

Autophagy. 2018;14(4):733-737. doi: 10.1080/15548627.2018.1432327. Epub 2018 Mar 13. Review.

20.

Homeostatic interplay between FoxO proteins and ER proteostasis in cancer and other diseases.

González-Quiroz M, Urra H, Limia CM, Hetz C.

Semin Cancer Biol. 2018 Jun;50:42-52. doi: 10.1016/j.semcancer.2018.01.011. Epub 2018 Jan 31. Review.

PMID:
29369790

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