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Items: 1 to 20 of 41

1.

Performance Characteristics of a Novel Vibration Technique for the Densification of a Powder Bed within a Die of a Rotary Tablet Press - a Proof of Concept.

Kalies A, Özcoban H, Leopold CS.

AAPS PharmSciTech. 2019 Mar 20;20(4):148. doi: 10.1208/s12249-019-1351-x.

PMID:
30895389
2.
3.

In situ co-amorphisation in coated tablets - The combination of carvedilol with aspartic acid during immersion in an acidic medium.

Petry I, Löbmann K, Grohganz H, Rades T, Leopold CS.

Int J Pharm. 2019 Mar 10;558:357-366. doi: 10.1016/j.ijpharm.2018.12.091. Epub 2019 Jan 12.

PMID:
30641182
4.

In situ co-amorphisation of arginine with indomethacin or furosemide during immersion in an acidic medium - A proof of concept study.

Petry I, Löbmann K, Grohganz H, Rades T, Leopold CS.

Eur J Pharm Biopharm. 2018 Dec;133:151-160. doi: 10.1016/j.ejpb.2018.10.011. Epub 2018 Oct 16.

PMID:
30339888
5.

Factors influencing the properties and the stability of spray-dried Sennae fructus extracts.

Zier KI, Schultze W, Leopold CS.

Drug Dev Ind Pharm. 2018 Oct;44(10):1659-1667. doi: 10.1080/03639045.2018.1483397. Epub 2018 Aug 8.

PMID:
29954227
6.

Undesired co-amorphisation of indomethacin and arginine during combined storage at high humidity conditions.

Petry I, Löbmann K, Grohganz H, Rades T, Leopold CS.

Int J Pharm. 2018 Jun 10;544(1):172-180. doi: 10.1016/j.ijpharm.2018.04.026. Epub 2018 Apr 15.

PMID:
29669257
7.

A comparative study on the sticking tendency of ibuprofen and ibuprofen sodium dihydrate to differently coated tablet punches.

Al-Karawi C, Leopold CS.

Eur J Pharm Biopharm. 2018 Jul;128:107-118. doi: 10.1016/j.ejpb.2018.04.004. Epub 2018 Apr 7.

PMID:
29635014
8.

Investigation of the tableting behavior of Ibuprofen DC 85 W.

Al-Karawi C, Cech T, Bang F, Leopold CS.

Drug Dev Ind Pharm. 2018 Aug;44(8):1262-1272. doi: 10.1080/03639045.2018.1442846. Epub 2018 Mar 22.

PMID:
29499616
9.

A non-destructive method for quality control of the pellet distribution within a MUPS tablet by terahertz pulsed imaging.

Novikova A, Markl D, Zeitler JA, Rades T, Leopold CS.

Eur J Pharm Sci. 2018 Jan 1;111:549-555. doi: 10.1016/j.ejps.2017.10.029. Epub 2017 Oct 19.

10.

UV imaging of multiple unit pellet system (MUPS) tablets: A case study of acetylsalicylic acid stability.

Novikova A, Carstensen JM, Rades T, Leopold CS.

Eur J Pharm Biopharm. 2017 Oct;119:447-453. doi: 10.1016/j.ejpb.2017.08.002. Epub 2017 Aug 2.

PMID:
28780276
11.

A novel technique for the visualization of tablet punch surfaces: Characterization of surface modification, wear and sticking.

Al-Karawi C, Kaiser T, Leopold CS.

Int J Pharm. 2017 Sep 15;530(1-2):440-454. doi: 10.1016/j.ijpharm.2017.08.006. Epub 2017 Aug 3.

PMID:
28779987
12.

Solid state properties and drug release behavior of co-amorphous indomethacin-arginine tablets coated with Kollicoat® Protect.

Petry I, Löbmann K, Grohganz H, Rades T, Leopold CS.

Eur J Pharm Biopharm. 2017 Oct;119:150-160. doi: 10.1016/j.ejpb.2017.06.007. Epub 2017 Jun 8.

PMID:
28602869
13.

Improvement of the physicochemical properties of Co-amorphous naproxen-indomethacin by naproxen-sodium.

Beyer A, Grohganz H, Löbmann K, Rades T, Leopold CS.

Int J Pharm. 2017 Jun 30;526(1-2):88-94. doi: 10.1016/j.ijpharm.2017.04.011. Epub 2017 Apr 6.

PMID:
28392278
14.

Multispectral UV Imaging for Determination of the Tablet Coating Thickness.

Novikova A, Carstensen JM, Zeitler JA, Rades T, Leopold CS.

J Pharm Sci. 2017 Jun;106(6):1560-1569. doi: 10.1016/j.xphs.2017.02.016. Epub 2017 Mar 1.

PMID:
28259766
15.

Influence of the cooling rate and the blend ratio on the physical stability of co-amorphous naproxen/indomethacin.

Beyer A, Grohganz H, Löbmann K, Rades T, Leopold CS.

Eur J Pharm Biopharm. 2016 Dec;109:140-148. doi: 10.1016/j.ejpb.2016.10.002. Epub 2016 Oct 13.

PMID:
27746228
16.

Preparation and recrystallization behavior of spray-dried co-amorphous naproxen-indomethacin.

Beyer A, Radi L, Grohganz H, Löbmann K, Rades T, Leopold CS.

Eur J Pharm Biopharm. 2016 Jul;104:72-81. doi: 10.1016/j.ejpb.2016.04.019. Epub 2016 Apr 26.

PMID:
27130786
17.

Rapid Assessment of Tablet Film Coating Quality by Multispectral UV Imaging.

Klukkert M, Wu JX, Rantanen J, Rehder S, Carstensen JM, Rades T, Leopold CS.

AAPS PharmSciTech. 2016 Aug;17(4):958-67. doi: 10.1208/s12249-015-0414-x. Epub 2015 Oct 13.

PMID:
26729525
18.

Multispectral UV imaging for fast and non-destructive quality control of chemical and physical tablet attributes.

Klukkert M, Wu JX, Rantanen J, Carstensen JM, Rades T, Leopold CS.

Eur J Pharm Sci. 2016 Jul 30;90:85-95. doi: 10.1016/j.ejps.2015.12.004. Epub 2015 Dec 3.

PMID:
26657202
19.

Multivariate Quantification of the Solid State Phase Composition of Co-Amorphous Naproxen-Indomethacin.

Beyer A, Grohganz H, Löbmann K, Rades T, Leopold CS.

Molecules. 2015 Oct 27;20(10):19571-87. doi: 10.3390/molecules201019571.

20.

Influence of Tableting on the Conformation and Thermal Stability of Trypsin as a Model Protein.

Klukkert M, van de Weert M, Fanø M, Rades T, Leopold CS.

J Pharm Sci. 2015 Dec;104(12):4314-4321. doi: 10.1002/jps.24672. Epub 2015 Oct 13.

PMID:
26462015

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