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Nandrolone induces a stem cell-like phenotype in human hepatocarcinoma-derived cell line inhibiting mitochondrial respiratory activity.

Agriesti F, Tataranni T, Pacelli C, Scrima R, Laurenzana I, Ruggieri V, Cela O, Mazzoccoli C, Salerno M, Sessa F, Sani G, Pomara C, Capitanio N, Piccoli C.

Sci Rep. 2020 Feb 10;10(1):2287. doi: 10.1038/s41598-020-58871-1.


A joint molecular networking study of a Smenospongia sponge and a cyanobacterial bloom revealed new antiproliferative chlorinated polyketides.

Teta R, Sala GD, Esposito G, Via CW, Mazzoccoli C, Piccoli C, Bertin MJ, Costantino V, Mangoni A.

Org Chem Front. 2019 Jun 7;6(11):1762-1774. doi: 10.1039/C9QO00074G. Epub 2019 Apr 11.


Dichloroacetate (DCA) and Cancer: An Overview towards Clinical Applications.

Tataranni T, Piccoli C.

Oxid Med Cell Longev. 2019 Nov 14;2019:8201079. doi: 10.1155/2019/8201079. eCollection 2019. Review.


In Vitro Antiproliferative Evaluation of Synthetic Meroterpenes Inspired by Marine Natural Products.

Imperatore C, Della Sala G, Casertano M, Luciano P, Aiello A, Laurenzana I, Piccoli C, Menna M.

Mar Drugs. 2019 Dec 5;17(12). pii: E684. doi: 10.3390/md17120684.


Gap Junction Intercellular Communication in the Carcinogenesis Hallmarks: Is This a Phenomenon or Epiphenomenon?

Zefferino R, Piccoli C, Gioia SD, Capitanio N, Conese M.

Cells. 2019 Aug 14;8(8). pii: E896. doi: 10.3390/cells8080896. Review.


Deferasirox drives ROS-mediated differentiation and induces interferon-stimulated gene expression in human healthy haematopoietic stem/progenitor cells and in leukemia cells.

Tataranni T, Mazzoccoli C, Agriesti F, De Luca L, Laurenzana I, Simeon V, Ruggieri V, Pacelli C, Della Sala G, Musto P, Capitanio N, Piccoli C.

Stem Cell Res Ther. 2019 Jun 13;10(1):171. doi: 10.1186/s13287-019-1293-y.


Parkin Mutation Affects Clock Gene-Dependent Energy Metabolism.

Pacelli C, Rotundo G, Lecce L, Menga M, Bidollari E, Scrima R, Cela O, Piccoli C, Cocco T, Vescovi AL, Mazzoccoli G, Rosati J, Capitanio N.

Int J Mol Sci. 2019 Jun 5;20(11). pii: E2772. doi: 10.3390/ijms20112772.


Dichloroacetate Affects Mitochondrial Function and Stemness-Associated Properties in Pancreatic Cancer Cell Lines.

Tataranni T, Agriesti F, Pacelli C, Ruggieri V, Laurenzana I, Mazzoccoli C, Sala GD, Panebianco C, Pazienza V, Capitanio N, Piccoli C.

Cells. 2019 May 18;8(5). pii: E478. doi: 10.3390/cells8050478.


Studying Werner syndrome to elucidate mechanisms and therapeutics of human aging and age-related diseases.

Lautrup S, Caponio D, Cheung HH, Piccoli C, Stevnsner T, Chan WY, Fang EF.

Biogerontology. 2019 Jun;20(3):255-269. doi: 10.1007/s10522-019-09798-2. Epub 2019 Jan 21. Review.


Clogging the Ubiquitin-Proteasome Machinery with Marine Natural Products: Last Decade Update.

Della Sala G, Agriesti F, Mazzoccoli C, Tataranni T, Costantino V, Piccoli C.

Mar Drugs. 2018 Nov 26;16(12). pii: E467. doi: 10.3390/md16120467. Review.


Mitochondria confirmed as drivers of HSC fate.

Piccoli C, Capitanio N.

Blood. 2018 Aug 30;132(9):878-880. doi: 10.1182/blood-2018-07-861708. No abstract available.


Targeting Endoplasmic Reticulum and/or Mitochondrial Ca2+ Fluxes as Therapeutic Strategy for HCV Infection.

Scrima R, Piccoli C, Moradpour D, Capitanio N.

Front Chem. 2018 Mar 21;6:73. doi: 10.3389/fchem.2018.00073. eCollection 2018.


Possible Mechanisms of Mercury Toxicity and Cancer Promotion: Involvement of Gap Junction Intercellular Communications and Inflammatory Cytokines.

Zefferino R, Piccoli C, Ricciardi N, Scrima R, Capitanio N.

Oxid Med Cell Longev. 2017;2017:7028583. doi: 10.1155/2017/7028583. Epub 2017 Dec 21. Review.


Febrile temperature reprograms by redox-mediated signaling the mitochondrial metabolic phenotype in monocyte-derived dendritic cells.

Menga M, Trotta R, Scrima R, Pacelli C, Silvestri V, Piccoli C, Capitanio N, Liso A.

Biochim Biophys Acta Mol Basis Dis. 2018 Mar;1864(3):685-699. doi: 10.1016/j.bbadis.2017.12.010. Epub 2017 Dec 12.


Para-hydroxyphenylpyruvate inhibits the pro-inflammatory stimulation of macrophage preventing LPS-mediated nitro-oxidative unbalance and immunometabolic shift.

Scrima R, Menga M, Pacelli C, Agriesti F, Cela O, Piccoli C, Cotoia A, De Gregorio A, Gefter JV, Cinnella G, Capitanio N.

PLoS One. 2017 Nov 27;12(11):e0188683. doi: 10.1371/journal.pone.0188683. eCollection 2017.


3-Aroyl-1,4-diarylpyrroles Inhibit Chronic Myeloid Leukemia Cell Growth through an Interaction with Tubulin.

La Regina G, Bai R, Coluccia A, Famiglini V, Passacantilli S, Naccarato V, Ortar G, Mazzoccoli C, Ruggieri V, Agriesti F, Piccoli C, Tataranni T, Nalli M, Brancale A, Vultaggio S, Mercurio C, Varasi M, Saponaro C, Sergio S, Maffia M, Coluccia AML, Hamel E, Silvestri R.

ACS Med Chem Lett. 2017 Apr 26;8(5):521-526. doi: 10.1021/acsmedchemlett.7b00022. eCollection 2017 May 11.


Rewiring carbohydrate catabolism differentially affects survival of pancreatic cancer cell lines with diverse metabolic profiles.

Tataranni T, Agriesti F, Ruggieri V, Mazzoccoli C, Simeon V, Laurenzana I, Scrima R, Pazienza V, Capitanio N, Piccoli C.

Oncotarget. 2017 Jun 20;8(25):41265-41281. doi: 10.18632/oncotarget.17172.


Ultrasound attenuation of lactobacilli and bifidobacteria: Effect on some technological and probiotic properties.

Racioppo A, Corbo MR, Piccoli C, Sinigaglia M, Speranza B, Bevilacqua A.

Int J Food Microbiol. 2017 Feb 21;243:78-83. doi: 10.1016/j.ijfoodmicro.2016.12.011. Epub 2016 Dec 21.


Clock-genes and mitochondrial respiratory activity: Evidence of a reciprocal interplay.

Scrima R, Cela O, Merla G, Augello B, Rubino R, Quarato G, Fugetto S, Menga M, Fuhr L, Relógio A, Piccoli C, Mazzoccoli G, Capitanio N.

Biochim Biophys Acta. 2016 Aug;1857(8):1344-1351. doi: 10.1016/j.bbabio.2016.03.035. Epub 2016 Apr 7.


N-acetylaspartate (NAA) induces neuronal differentiation of SH-SY5Y neuroblastoma cell line and sensitizes it to chemotherapeutic agents.

Mazzoccoli C, Ruggieri V, Tataranni T, Agriesti F, Laurenzana I, Fratello A, Capitanio N, Piccoli C.

Oncotarget. 2016 May 3;7(18):26235-46. doi: 10.18632/oncotarget.8454.

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