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Items: 1 to 20 of 46


Modulating Hinge Flexibility in the APP Transmembrane Domain Alters γ-Secretase Cleavage.

Götz A, Mylonas N, Högel P, Silber M, Heinel H, Menig S, Vogel A, Feyrer H, Huster D, Luy B, Langosch D, Scharnagl C, Muhle-Goll C, Kamp F, Steiner H.

Biophys J. 2019 Jun 4;116(11):2103-2120. doi: 10.1016/j.bpj.2019.04.030. Epub 2019 May 3.


Increased H-Bond Stability Relates to Altered ε-Cleavage Efficiency and Aβ Levels in the I45T Familial Alzheimer's Disease Mutant of APP.

Götz A, Högel P, Silber M, Chaitoglou I, Luy B, Muhle-Goll C, Scharnagl C, Langosch D.

Sci Rep. 2019 Mar 29;9(1):5321. doi: 10.1038/s41598-019-41766-1.


Efficient Extraction from Mice Feces for NMR Metabolomics Measurements with Special Emphasis on SCFAs.

Hauser A, Eisenmann P, Muhle-Goll C, Luy B, Dötsch A, Graf D, Tzvetkova P.

Metabolites. 2019 Mar 21;9(3). pii: E55. doi: 10.3390/metabo9030055.


Integrated Process for the Enzymatic Production of Fatty Acid Sugar Esters Completely Based on Lignocellulosic Substrates.

Siebenhaller S, Kirchhoff J, Kirschhöfer F, Brenner-Weiß G, Muhle-Goll C, Luy B, Haitz F, Hahn T, Zibek S, Syldatk C, Ochsenreither K.

Front Chem. 2018 Sep 13;6:421. doi: 10.3389/fchem.2018.00421. eCollection 2018.


Lipase-Catalyzed Synthesis of Sugar Esters in Honey and Agave Syrup.

Siebenhaller S, Gentes J, Infantes A, Muhle-Goll C, Kirschhöfer F, Brenner-Weiß G, Ochsenreither K, Syldatk C.

Front Chem. 2018 Feb 12;6:24. doi: 10.3389/fchem.2018.00024. eCollection 2018.


Development of Bag-1L as a therapeutic target in androgen receptor-dependent prostate cancer.

Cato L, Neeb A, Sharp A, Buzón V, Ficarro SB, Yang L, Muhle-Goll C, Kuznik NC, Riisnaes R, Nava Rodrigues D, Armant O, Gourain V, Adelmant G, Ntim EA, Westerling T, Dolling D, Rescigno P, Figueiredo I, Fauser F, Wu J, Rottenberg JT, Shatkina L, Ester C, Luy B, Puchta H, Troppmair J, Jung N, Bräse S, Strähle U, Marto JA, Nienhaus GU, Al-Lazikani B, Salvatella X, de Bono JS, Cato AC, Brown M.

Elife. 2017 Aug 10;6. pii: e27159. doi: 10.7554/eLife.27159.


Beechwood carbohydrates for enzymatic synthesis of sustainable glycolipids.

Siebenhaller S, Hajek T, Muhle-Goll C, Himmelsbach M, Luy B, Kirschhöfer F, Brenner-Weiß G, Hahn T, Zibek S, Syldatk C.

Bioresour Bioprocess. 2017;4(1):25. doi: 10.1186/s40643-017-0155-7. Epub 2017 Jun 7.


Untargeted NMR Spectroscopic Analysis of the Metabolic Variety of New Apple Cultivars.

Eisenmann P, Ehlers M, Weinert CH, Tzvetkova P, Silber M, Rist MJ, Luy B, Muhle-Goll C.

Metabolites. 2016 Sep 19;6(3). pii: E29. doi: 10.3390/metabo6030029.


Profiling human blood serum metabolites by nuclear magnetic resonance spectroscopy: a comprehensive tool for the evaluation of hemodialysis efficiency.

Kromke M, Palomino-Schätzlein M, Mayer H, Pfeffer S, Pineda-Lucena A, Luy B, Hausberg M, Muhle-Goll C.

Transl Res. 2016 May;171:71-82.e1-9. doi: 10.1016/j.trsl.2016.02.003. Epub 2016 Feb 10.


Glycolipids produced by Rouxiella sp. DSM 100043 and isolation of the biosurfactants via foam-fractionation.

Kügler JH, Muhle-Goll C, Hansen SH, Völp AR, Kirschhöfer F, Kühl B, Brenner-Weiss G, Luy B, Syldatk C, Hausmann R.

AMB Express. 2015 Dec;5(1):82. doi: 10.1186/s13568-015-0167-7. Epub 2015 Dec 23.


Menthols as Chiral Auxiliaries for Asymmetric Cycloadditive Oligomerization: Syntheses and Studies of β-Proline Hexamers.

Kudryavtsev KV, Ivantcova PM, Muhle-Goll C, Churakov AV, Sokolov MN, Dyuba AV, Arutyunyan AM, Howard JA, Yu CC, Guh JH, Zefirov NS, Bräse S.

Org Lett. 2015 Dec 18;17(24):6178-81. doi: 10.1021/acs.orglett.5b03154. Epub 2015 Dec 1.


Extracellular aromatic biosurfactant produced by Tsukamurella pseudospumae and T. spumae during growth on n-hexadecane.

Kügler JH, Kraft A, Heißler S, Muhle-Goll C, Luy B, Schwack W, Syldatk C, Hausmann R.

J Biotechnol. 2015 Oct 10;211:107-14. doi: 10.1016/j.jbiotec.2015.06.424. Epub 2015 Jul 26.


Autoinduced catalysis and inverse equilibrium isotope effect in the frustrated Lewis pair catalyzed hydrogenation of imines.

Tussing S, Greb L, Tamke S, Schirmer B, Muhle-Goll C, Luy B, Paradies J.

Chemistry. 2015 May 26;21(22):8056-9. doi: 10.1002/chem.201500805. Epub 2015 Apr 15.


Dendrimer-type peptoid-decorated hexaphenylxylenes and tetraphenylmethanes: synthesis and structure in solution and in the gas phase.

Peschko K, Schade A, Vollrath SB, Schwarz U, Luy B, Muhle-Goll C, Weis P, Bräse S.

Chemistry. 2014 Dec 1;20(49):16273-8. doi: 10.1002/chem.201404024. Epub 2014 Oct 8.


Trehalose lipid biosurfactants produced by the actinomycetes Tsukamurella spumae and T. pseudospumae.

Kügler JH, Muhle-Goll C, Kühl B, Kraft A, Heinzler R, Kirschhöfer F, Henkel M, Wray V, Luy B, Brenner-Weiss G, Lang S, Syldatk C, Hausmann R.

Appl Microbiol Biotechnol. 2014 Nov;98(21):8905-15. doi: 10.1007/s00253-014-5972-4. Epub 2014 Aug 5.


Structure of the membrane anchor of pestivirus glycoprotein E(rns), a long tilted amphipathic helix.

Aberle D, Muhle-Goll C, Bürck J, Wolf M, Reißer S, Luy B, Wenzel W, Ulrich AS, Meyers G.

PLoS Pathog. 2014 Feb 27;10(2):e1003973. doi: 10.1371/journal.ppat.1003973. eCollection 2014 Feb.


Coregulator control of androgen receptor action by a novel nuclear receptor-binding motif.

Jehle K, Cato L, Neeb A, Muhle-Goll C, Jung N, Smith EW, Buzon V, Carbó LR, Estébanez-Perpiñá E, Schmitz K, Fruk L, Luy B, Chen Y, Cox MB, Bräse S, Brown M, Cato AC.

J Biol Chem. 2014 Mar 28;289(13):8839-51. doi: 10.1074/jbc.M113.534859. Epub 2014 Feb 12.


Alternating asymmetric self-induction in functionalized pyrrolidine oligomers.

Kudryavtsev KV, Ivantcova PM, Churakov AV, Wiedmann S, Luy B, Muhle-Goll C, Zefirov NS, Bräse S.

Angew Chem Int Ed Engl. 2013 Nov 25;52(48):12736-40. doi: 10.1002/anie.201302862. Epub 2013 Oct 10. No abstract available.


Influence of Freezing and Storage Procedure on Human Urine Samples in NMR-Based Metabolomics.

Rist MJ, Muhle-Goll C, Görling B, Bub A, Heissler S, Watzl B, Luy B.

Metabolites. 2013 Apr 9;3(2):243-58. doi: 10.3390/metabo3020243.


Structural characterization of a peptoid with lysine-like side chains and biological activity using NMR and computational methods.

Sternberg U, Birtalan E, Jakovkin I, Luy B, Schepers U, Bräse S, Muhle-Goll C.

Org Biomol Chem. 2013 Jan 28;11(4):640-7. doi: 10.1039/c2ob27039k. Epub 2012 Dec 5.


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