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Items: 1 to 20 of 26

1.

Human Umbilical Cord Mesenchymal Stromal Cells Attenuate Systemic Sepsis in Part by Enhancing Peritoneal Macrophage Bacterial Killing via Heme Oxygenase-1 Induction in Rats.

Jerkic M, Gagnon S, Rabani R, Ward-Able T, Masterson C, Otulakowski G, Curley GF, Marshall J, Kavanagh BP, Laffey JG.

Anesthesiology. 2020 Jan;132(1):140-154. doi: 10.1097/ALN.0000000000003018.

PMID:
31764154
2.

Nebulized Mesenchymal Stem Cell Derived Conditioned Medium Retains Antibacterial Properties Against Clinical Pathogen Isolates.

McCarthy SD, Horgan E, Ali A, Masterson C, Laffey JG, MacLoughlin R, O'Toole D.

J Aerosol Med Pulm Drug Deliv. 2019 Nov 15. doi: 10.1089/jamp.2019.1542. [Epub ahead of print]

PMID:
31730399
3.

Modulating the distribution and fate of exogenously delivered MSCs to enhance therapeutic potential: knowns and unknowns.

Masterson CH, Curley GF, Laffey JG.

Intensive Care Med Exp. 2019 Jul 25;7(Suppl 1):41. doi: 10.1186/s40635-019-0235-4. Review.

4.

Demographics, management and outcome of females and males with acute respiratory distress syndrome in the LUNG SAFE prospective cohort study.

McNicholas BA, Madotto F, Pham T, Rezoagli E, Masterson CH, Horie S, Bellani G, Brochard L, Laffey JG; LUNG SAFE Investigators and the ESICM Trials Group.

Eur Respir J. 2019 Oct 17;54(4). pii: 1900609. doi: 10.1183/13993003.00609-2019. Print 2019 Oct.

PMID:
31346004
5.

Overexpression of IL-10 Enhances the Efficacy of Human Umbilical-Cord-Derived Mesenchymal Stromal Cells in E. coli Pneumosepsis.

Jerkic M, Masterson C, Ormesher L, Gagnon S, Goyal S, Rabani R, Otulakowski G, Zhang H, Kavanagh BP, Laffey JG.

J Clin Med. 2019 Jun 13;8(6). pii: E847. doi: 10.3390/jcm8060847.

6.

Extracellular Vesicles from Interferon-γ-primed Human Umbilical Cord Mesenchymal Stromal Cells Reduce Escherichia coli-induced Acute Lung Injury in Rats.

Varkouhi AK, Jerkic M, Ormesher L, Gagnon S, Goyal S, Rabani R, Masterson C, Spring C, Chen PZ, Gu FX, Dos Santos CC, Curley GF, Laffey JG.

Anesthesiology. 2019 May;130(5):778-790. doi: 10.1097/ALN.0000000000002655.

PMID:
30870158
7.

Cell therapy in acute respiratory distress syndrome.

Horie S, Gonzalez HE, Laffey JG, Masterson CH.

J Thorac Dis. 2018 Sep;10(9):5607-5620. doi: 10.21037/jtd.2018.08.28. Review.

8.

Sepsis: Therapeutic Potential of Immunosuppression versus Immunostimulation.

Rezoagli E, Masterson CH, McCarthy SD, Laffey JG.

Am J Respir Cell Mol Biol. 2019 Jan;60(1):128-130. doi: 10.1165/rcmb.2018-0284RO. No abstract available.

PMID:
30230345
9.

Syndecan-2-positive, Bone Marrow-derived Human Mesenchymal Stromal Cells Attenuate Bacterial-induced Acute Lung Injury and Enhance Resolution of Ventilator-induced Lung Injury in Rats.

Masterson C, Devaney J, Horie S, O'Flynn L, Deedigan L, Elliman S, Barry F, O'Brien T, O'Toole D, Laffey JG.

Anesthesiology. 2018 Sep;129(3):502-516. doi: 10.1097/ALN.0000000000002327.

PMID:
29979191
10.

Mesenchymal stem cells enhance NOX2-dependent reactive oxygen species production and bacterial killing in macrophages during sepsis.

Rabani R, Volchuk A, Jerkic M, Ormesher L, Garces-Ramirez L, Canton J, Masterson C, Gagnon S, Tatham KC, Marshall J, Grinstein S, Laffey JG, Szaszi K, Curley GF.

Eur Respir J. 2018 Apr 26;51(4). pii: 1702021. doi: 10.1183/13993003.02021-2017. Print 2018 Apr.

11.

Mechanical Ventilation Induces Desensitization of Lung Axl Tyrosine Kinase Receptors.

Otulakowski G, Engelberts D, Post M, Masterson C, Kavanagh BP.

Anesthesiology. 2018 Jul;129(1):143-153. doi: 10.1097/ALN.0000000000002140.

PMID:
29474201
12.

Hypercapnic Acidosis Regulates Mer Tyrosine Kinase Receptor Shedding and Activity.

Otulakowski G, Engelberts D, Post M, Masterson C, Kavanagh BP.

Am J Respir Cell Mol Biol. 2018 Jan;58(1):132-134. doi: 10.1165/rcmb.2017-0316LE. No abstract available.

PMID:
29286859
13.

The authors reply.

Curley GF, Jerkic M, Hogan G, Masterson C, O'Toole D, Devaney J, Laffey JG.

Crit Care Med. 2017 Jul;45(7):e737-e738. doi: 10.1097/CCM.0000000000002480. No abstract available.

PMID:
28622234
14.

Cryopreserved, Xeno-Free Human Umbilical Cord Mesenchymal Stromal Cells Reduce Lung Injury Severity and Bacterial Burden in Rodent Escherichia coli-Induced Acute Respiratory Distress Syndrome.

Curley GF, Jerkic M, Dixon S, Hogan G, Masterson C, O'Toole D, Devaney J, Laffey JG.

Crit Care Med. 2017 Feb;45(2):e202-e212. doi: 10.1097/CCM.0000000000002073.

PMID:
27861182
15.

Hypercapnic acidosis attenuates pulmonary epithelial stretch-induced injury via inhibition of the canonical NF-κB pathway.

Horie S, Ansari B, Masterson C, Devaney J, Scully M, O'Toole D, Laffey JG.

Intensive Care Med Exp. 2016 Dec;4(1):8. doi: 10.1186/s40635-016-0081-6. Epub 2016 Mar 22.

16.

Stem cell therapy for acute respiratory distress syndrome: a promising future?

Horie S, Masterson C, Devaney J, Laffey JG.

Curr Opin Crit Care. 2016 Feb;22(1):14-20. doi: 10.1097/MCC.0000000000000276. Review.

PMID:
26645555
17.

Effects and Mechanisms by Which Hypercapnic Acidosis Inhibits Sepsis-Induced Canonical Nuclear Factor-κB Signaling in the Lung.

Masterson C, O'Toole D, Leo A, McHale P, Horie S, Devaney J, Laffey JG.

Crit Care Med. 2016 Apr;44(4):e207-17. doi: 10.1097/CCM.0000000000001376.

PMID:
26584194
18.

Mesenchymal stromal cells are more effective than the MSC secretome in diminishing injury and enhancing recovery following ventilator-induced lung injury.

Hayes M, Curley GF, Masterson C, Devaney J, O'Toole D, Laffey JG.

Intensive Care Med Exp. 2015 Dec;3(1):29. doi: 10.1186/s40635-015-0065-y. Epub 2015 Oct 15.

19.

Human mesenchymal stromal cells decrease the severity of acute lung injury induced by E. coli in the rat.

Devaney J, Horie S, Masterson C, Elliman S, Barry F, O'Brien T, Curley GF, O'Toole D, Laffey JG.

Thorax. 2015 Jul;70(7):625-35. doi: 10.1136/thoraxjnl-2015-206813. Epub 2015 May 18.

PMID:
25986435
20.

Hypercapnia: clinical relevance and mechanisms of action.

Masterson C, Otulakowski G, Kavanagh BP.

Curr Opin Crit Care. 2015 Feb;21(1):7-12. doi: 10.1097/MCC.0000000000000164. Review.

PMID:
25546531

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