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Items: 1 to 20 of 55

1.

Byrsonima intermedia A. Juss partitions promote gastroprotection against peptic ulcers and improve healing through antioxidant and anti-inflammatory activities.

de Cássia Dos Santos R, Bonamin F, Périco LL, Rodrigues VP, Zanatta AC, Rodrigues CM, Sannomiya M, Dos Santos Ramos MA, Bonifácio BV, Bauab TM, Tamashiro J, da Rocha LRM, Vilegas W, Hiruma-Lima CA.

Biomed Pharmacother. 2019 Mar;111:1112-1123. doi: 10.1016/j.biopha.2018.12.132. Epub 2019 Jan 12.

2.

Genotoxic effects induced by beta-myrcene following metabolism by liver HepG2/C3A human cells.

Orlando JB, Silva BO, Pires-Cunha CL, Hiruma-Lima CA, Gaivão IOM, Maistro EL.

J Toxicol Environ Health A. 2019;82(3):176-185. doi: 10.1080/15287394.2019.1577195. Epub 2019 Feb 26.

PMID:
30806179
3.

Can the gastric healing effect of Eugenia punicifolia be the same in male and female rats?

Périco LL, Rodrigues VP, Ohara R, Nunes VVA, da Rocha LRM, Vilegas W, Dos Santos C, Hiruma-Lima CA.

J Ethnopharmacol. 2019 May 10;235:268-278. doi: 10.1016/j.jep.2019.02.012. Epub 2019 Feb 11.

PMID:
30763697
4.

Chemical constituents and allelopathic activity of Machaerium eriocarpum Benth.

Bento CC, Tangerina MMP, Zanatta AC, Sartori ÂLB, Franco DM, Hiruma-Lima CA, Vilegas W, de Almeida LFR, Sannomiya M.

Nat Prod Res. 2018 Nov 20:1-5. doi: 10.1080/14786419.2018.1508136. [Epub ahead of print]

PMID:
30453777
5.

Sex-specific effects of Eugenia punicifolia extract on gastric ulcer healing in rats.

Périco LL, Rodrigues VP, Ohara R, Bueno G, Nunes VVA, Dos Santos RC, Camargo ACL, Justulin Júnior LA, de Andrade SF, Steimbach VMB, da Silva LM, da Rocha LRM, Vilegas W, Dos Santos C, Hiruma-Lima CA.

World J Gastroenterol. 2018 Oct 14;24(38):4369-4383. doi: 10.3748/wjg.v24.i38.4369.

6.

Multielement analysis of plant extracts with potential use in the treatment of peptic ulcers by synchrotron radiation total reflection X-ray fluorescence.

Vieira LD, da Silva KT, Giarola RS, Inocente GF, Kushima H, Hiruma Lima CA, Hormaza JM.

PeerJ. 2018 Sep 12;6:e5375. doi: 10.7717/peerj.5375. eCollection 2018.

7.

Involvement of Opioid System, TRPM8, and ASIC Receptors in Antinociceptive Effect of Arrabidaea brachypoda (DC) Bureau.

Rodrigues VP, Rocha CQD, Périco LL, Santos RCD, Ohara R, Nishijima CM, Ferreira Queiroz E, Wolfender JL, Rocha LRMD, Santos ARS, Vilegas W, Hiruma-Lima CA.

Int J Mol Sci. 2017 Nov 2;18(11). pii: E2304. doi: 10.3390/ijms18112304.

8.

Anti-inflammatory intestinal activity of Combretum duarteanum Cambess. in trinitrobenzene sulfonic acid colitis model.

de Morais Lima GR, Machado FD, Périco LL, de Faria FM, Luiz-Ferreira A, Souza Brito AR, Pellizzon CH, Hiruma-Lima CA, Tavares JF, Barbosa Filho JM, Batista LM.

World J Gastroenterol. 2017 Feb 28;23(8):1353-1366. doi: 10.3748/wjg.v23.i8.1353.

9.

Corrigendum to "New steroidal saponins and antiulcer activity from Solanum paniculatum L." [Food Chem. 186 (2015) 160-167].

Vieira Júnior GM, da Rocha CQ, Rodrigues TS, Hiruma-Lima CA, Vilegas W.

Food Chem. 2017 Jan 1;214:745. doi: 10.1016/j.foodchem.2016.08.001. Epub 2016 Aug 6. No abstract available.

PMID:
27507533
10.

Cissus sicyoides: Pharmacological Mechanisms Involved in the Anti-Inflammatory and Antidiarrheal Activities.

Beserra FP, Santos Rde C, Périco LL, Rodrigues VP, Kiguti LR, Saldanha LL, Pupo AS, da Rocha LR, Dokkedal AL, Vilegas W, Hiruma-Lima CA.

Int J Mol Sci. 2016 Jan 23;17(2). pii: E149. doi: 10.3390/ijms17020149.

11.

Ulcer healing and mechanism(s) of action involved in the gastroprotective activity of fractions obtained from Syngonanthus arthrotrichus and Syngonanthus bisulcatus.

Batista LM, Lima GR, De Almeida AB, Magri Lde P, Calvo TR, Ferreira AL, Pellizzon CH, Hiruma-Lima CA, Vilegas W, Sano PT, Brito AR.

BMC Complement Altern Med. 2015 Oct 29;15:391. doi: 10.1186/s12906-015-0923-x.

12.

Effect of Himatanthus sucuuba in Maternal Reproductive Outcome and Fetal Anomaly Frequency in Rats.

de Sousa Soares T, Damasceno DC, Kempinas Wde G, Resende FM, Correa dos Santos MA, Hiruma-Lima CA, Volpato GT.

Birth Defects Res B Dev Reprod Toxicol. 2015 Oct;104(5):190-5. doi: 10.1002/bdrb.21152. Epub 2015 Sep 4.

PMID:
26339763
13.

Does the gastroprotective action of a medicinal plant ensure healing effects? An integrative study of the biological effects of Serjania marginata Casar. (Sapindaceae) in rats.

Périco LL, Heredia-Vieira SC, Beserra FP, de Cássia Dos Santos R, Weiss MB, Resende FA, Dos Santos Ramos MA, Bonifácio BV, Bauab TM, Varanda EA, de Gobbi JI, da Rocha LR, Vilegas W, Hiruma-Lima CA.

J Ethnopharmacol. 2015 Aug 22;172:312-24. doi: 10.1016/j.jep.2015.06.025. Epub 2015 Jun 20.

PMID:
26099637
14.

The Anti-Inflammatory Effects of the Methanolic Extract and Fractions from Davilla elliptica St. Hil. (Dilleniaceae) on Bothrops jararaca Envenomation.

Nishijima CM, Delella FK, Rodrigues CM, Rinaldo D, Lopes-Ferreira MV, da Rocha LR, Vilegas W, Felisbino SL, Hiruma-Lima CA.

Int J Mol Sci. 2015 Jun 2;16(6):12454-66. doi: 10.3390/ijms160612454.

15.

New steroidal saponin and antiulcer activity from Solanum paniculatum L.

Vieira Júnior GM, da Rocha CQ, de Souza Rodrigues T, Hiruma-Lima CA, Vilegas W.

Food Chem. 2015 Nov 1;186:160-7. doi: 10.1016/j.foodchem.2014.08.005. Epub 2014 Aug 17. Erratum in: Food Chem. 2017 Jan 1;214:745.

PMID:
25976806
16.

Terminalia catappa L.: a medicinal plant from the Caribbean pharmacopeia with anti-Helicobacter pylori and antiulcer action in experimental rodent models.

Pinheiro Silva L, Damacena de Angelis C, Bonamin F, Kushima H, José Mininel F, Campaner Dos Santos L, Karina Delella F, Luis Felisbino S, Vilegas W, Regina Machado da Rocha L, Aparecido Dos Santos Ramos M, Maria Bauab T, Toma W, Akiko Hiruma-Lima C.

J Ethnopharmacol. 2015 Jan 15;159:285-95. doi: 10.1016/j.jep.2014.11.025. Epub 2014 Nov 24.

17.

Geraniol-a flavoring agent with multifunctional effects in protecting the gastric and duodenal mucosa.

de Carvalho KI, Bonamin F, Dos Santos RC, Périco LL, Beserra FP, de Sousa DP, Filho JM, da Rocha LR, Hiruma-Lima CA.

Naunyn Schmiedebergs Arch Pharmacol. 2014 Apr;387(4):355-65. doi: 10.1007/s00210-013-0947-z. Epub 2013 Dec 17.

PMID:
24337826
18.

Healing actions of essential oils from Citrus aurantium and d-limonene in the gastric mucosa: the roles of VEGF, PCNA, and COX-2 in cell proliferation.

Moraes TM, Rozza AL, Kushima H, Pellizzon CH, Rocha LR, Hiruma-Lima CA.

J Med Food. 2013 Dec;16(12):1162-7. doi: 10.1089/jmf.2012.0259.

PMID:
24328705
19.

Gastroprotective effects (in rodents) of a flavonoid rich fraction obtained from Syngonanthus macrolepsis.

Batista LM, de Almeida AB, Lima GR, Falcão Hde S, Magri Lde P, Luiz-Ferreira A, dos Santos LC, Hiruma-Lima CA, Vilegas W, Brito AR.

J Pharm Pharmacol. 2014 Mar;66(3):445-52. doi: 10.1111/jphp.12175. Epub 2013 Nov 17.

PMID:
24237033
20.

Antidiarrheal and intestinal antiinflammatory activities of a methanolic extract of Qualea parviflora Mart. in experimental models.

Mazzolin LP, Kiguti LR, da Maia EO, Fernandes LT, da Rocha LR, Vilegas W, Pupo AS, Di Stasi LC, Hiruma-Lima CA.

J Ethnopharmacol. 2013 Dec 12;150(3):1016-23. doi: 10.1016/j.jep.2013.10.006. Epub 2013 Oct 21.

PMID:
24157378

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