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Items: 17


Polyethers isolated from the marine actinobacterium Streptomyces cacaoi inhibit autophagy and induce apoptosis in cancer cells.

Khan N, Yılmaz S, Aksoy S, Uzel A, Tosun Ç, Kirmizibayrak PB, Bedir E.

Chem Biol Interact. 2019 Jul 1;307:167-178. doi: 10.1016/j.cbi.2019.04.035. Epub 2019 May 3.


Sur1-Trpm4 Cation Channel Expression in Human Cerebral Infarcts.

Mehta RI, Tosun C, Ivanova S, Tsymbalyuk N, Famakin BM, Kwon MS, Castellani RJ, Gerzanich V, Simard JM.

J Neuropathol Exp Neurol. 2015 Aug;74(8):835-49. doi: 10.1097/NEN.0000000000000223.


Angiogenesis induced by prenatal ischemia predisposes to periventricular hemorrhage during postnatal mechanical ventilation.

Tosun C, Hong C, Carusillo B, Ivanova S, Gerzanich V, Simard JM.

Pediatr Res. 2015 May;77(5):663-73. doi: 10.1038/pr.2015.34. Epub 2015 Feb 9.


Exposure of the thorax to a sublethal blast wave causes a hydrodynamic pulse that leads to perivenular inflammation in the brain.

Simard JM, Pampori A, Keledjian K, Tosun C, Schwartzbauer G, Ivanova S, Gerzanich V.

J Neurotrauma. 2014 Jul 15;31(14):1292-304. doi: 10.1089/neu.2013.3016. Epub 2014 Jun 3.


Biomarkers as outcome predictors in subarachnoid hemorrhage--a systematic review.

Hong CM, Tosun C, Kurland DB, Gerzanich V, Schreibman D, Simard JM.

Biomarkers. 2014 Mar;19(2):95-108. doi: 10.3109/1354750X.2014.881418. Epub 2014 Feb 5. Review.


Glibenclamide for the treatment of acute CNS injury.

Kurland DB, Tosun C, Pampori A, Karimy JK, Caffes NM, Gerzanich V, Simard JM.

Pharmaceuticals (Basel). 2013 Oct 11;6(10):1287-303. doi: 10.3390/ph6101287.


Inhibition of the Sur1-Trpm4 channel reduces neuroinflammation and cognitive impairment in subarachnoid hemorrhage.

Tosun C, Kurland DB, Mehta R, Castellani RJ, deJong JL, Kwon MS, Woo SK, Gerzanich V, Simard JM.

Stroke. 2013 Dec;44(12):3522-8. doi: 10.1161/STROKEAHA.113.002904. Epub 2013 Oct 10.


Sulfonylurea receptor 1 expression in human cerebral infarcts.

Mehta RI, Ivanova S, Tosun C, Castellani RJ, Gerzanich V, Simard JM.

J Neuropathol Exp Neurol. 2013 Sep;72(9):871-83. doi: 10.1097/NEN.0b013e3182a32e40.


The protective effect of glibenclamide in a model of hemorrhagic encephalopathy of prematurity.

Tosun C, Koltz MT, Kurland DB, Ijaz H, Gurakar M, Schwartzbauer G, Coksaygan T, Ivanova S, Gerzanich V, Simard JM.

Brain Sci. 2013 Mar 7;3(1):215-38. doi: 10.3390/brainsci3010215.


Heparin reduces neuroinflammation and transsynaptic neuronal apoptosis in a model of subarachnoid hemorrhage.

Simard JM, Tosun C, Ivanova S, Kurland DB, Hong C, Radecki L, Gisriel C, Mehta R, Schreibman D, Gerzanich V.

Transl Stroke Res. 2012 Jul;3(Suppl 1):155-65. doi: 10.1007/s12975-012-0166-9. Epub 2012 Apr 14.


Tandem insults of prenatal ischemia plus postnatal raised intrathoracic pressure in a novel rat model of encephalopathy of prematurity.

Koltz MT, Tosun C, Kurland DB, Coksaygan T, Castellani RJ, Ivanova S, Gerzanich V, Simard JM.

J Neurosurg Pediatr. 2011 Dec;8(6):628-39. doi: 10.3171/2011.9.PEDS11174.


Inflammation of the choroid plexus and ependymal layer of the ventricle following intraventricular hemorrhage.

Simard PF, Tosun C, Melnichenko L, Ivanova S, Gerzanich V, Simard JM.

Transl Stroke Res. 2011 Jun;2(2):227-31. doi: 10.1007/s12975-011-0070-8.


Rodent model of direct cranial blast injury.

Kuehn R, Simard PF, Driscoll I, Keledjian K, Ivanova S, Tosun C, Williams A, Bochicchio G, Gerzanich V, Simard JM.

J Neurotrauma. 2011 Oct;28(10):2155-69. doi: 10.1089/neu.2010.1532. Epub 2011 Aug 8.


Brief suppression of Abcc8 prevents autodestruction of spinal cord after trauma.

Simard JM, Woo SK, Norenberg MD, Tosun C, Chen Z, Ivanova S, Tsymbalyuk O, Bryan J, Landsman D, Gerzanich V.

Sci Transl Med. 2010 Apr 21;2(28):28ra29. doi: 10.1126/scitranslmed.3000522.


Novel model of frontal impact closed head injury in the rat.

Kilbourne M, Kuehn R, Tosun C, Caridi J, Keledjian K, Bochicchio G, Scalea T, Gerzanich V, Simard JM.

J Neurotrauma. 2009 Dec;26(12):2233-43. doi: 10.1089/neu.2009.0968.


Key role of sulfonylurea receptor 1 in progressive secondary hemorrhage after brain contusion.

Simard JM, Kilbourne M, Tsymbalyuk O, Tosun C, Caridi J, Ivanova S, Keledjian K, Bochicchio G, Gerzanich V.

J Neurotrauma. 2009 Dec;26(12):2257-67. doi: 10.1089/neu.2009.1021.


Glibenclamide reduces inflammation, vasogenic edema, and caspase-3 activation after subarachnoid hemorrhage.

Simard JM, Geng Z, Woo SK, Ivanova S, Tosun C, Melnichenko L, Gerzanich V.

J Cereb Blood Flow Metab. 2009 Feb;29(2):317-30. doi: 10.1038/jcbfm.2008.120. Epub 2008 Oct 15. Erratum in: J Cereb Blood Flow Metab. 2009 Apr;29(4):872.

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