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Items: 1 to 20 of 114


Cryo-EM structure of eastern equine encephalitis virus in complex with heparan sulfate analogues.

Chen CL, Hasan SS, Klose T, Sun Y, Buda G, Sun C, Klimstra WB, Rossmann MG.

Proc Natl Acad Sci U S A. 2020 Apr 3. pii: 201910670. doi: 10.1073/pnas.1910670117. [Epub ahead of print]


Arecoline suppresses RANKL-induced osteoclast differentiation in vitro and attenuates LPS-induced bone loss in vivo.

Liu FL, Chen CL, Lai CC, Lee CC, Chang DM.

Phytomedicine. 2020 Feb 22;69:153195. doi: 10.1016/j.phymed.2020.153195. [Epub ahead of print]


Single-Cell Proteomic Profiling Identifies Combined AXL and JAK1 Inhibition as a Novel Therapeutic Strategy for Lung Cancer.

Taverna JA, Hung CN, DeArmond DT, Chen M, Lin CL, Osmulski PA, Gaczynska ME, Wang CM, Lucio ND, Chou CW, Chen CL, Nazarullah A, Lampkin SR, Qiu L, Bearss DJ, Warner S, Whatcott CJ, Mouritsen L, Wade M, Weitman S, Mesa RA, Kirma NB, Chao WT, Huang TH.

Cancer Res. 2020 Apr 1;80(7):1551-1563. doi: 10.1158/0008-5472.CAN-19-3183. Epub 2020 Jan 28.


Attenuation of NAD[P]H:quinone oxidoreductase 1 aggravates prostate cancer and tumor cell plasticity through enhanced TGFβ signaling.

Thapa D, Huang SB, Muñoz AR, Yang X, Bedolla RG, Hung CN, Chen CL, Huang TH, Liss MA, Reddick RL, Miyamoto H, Kumar AP, Ghosh R.

Commun Biol. 2020 Jan 3;3(1):12. doi: 10.1038/s42003-019-0720-z.


Attenuation of NAD[P]H:quinone oxidoreductase 1 aggravates prostate cancer and tumor cell plasticity through enhanced TGFβ signaling.

Thapa D, Huang SB, Muñoz AR, Yang X, Bedolla RG, Hung CN, Chen CL, Huang TH, Liss MA, Reddick RL, Miyamoto H, Kumar AP, Ghosh R.

Commun Biol. 2020 Jan 3;3:12. doi: 10.1038/s42003-019-0720-z. eCollection 2020.


Spatial EGFR Dynamics and Metastatic Phenotypes Modulated by Upregulated EphB2 and Src Pathways in Advanced Prostate Cancer.

Liu YL, Horning AM, Lieberman B, Kim M, Lin CK, Hung CN, Chou CW, Wang CM, Lin CL, Kirma NB, Liss MA, Vasisht R, Perillo EP, Blocher K, Horng H, Taverna JA, Ruan J, Yankeelov TE, Dunn AK, Huang TH, Yeh HC, Chen CL.

Cancers (Basel). 2019 Dec 1;11(12). pii: E1910. doi: 10.3390/cancers11121910.


Molecular Subtyping of Clinically Localized Urothelial Carcinoma Reveals Lower Rates of Pathological Upstaging at Radical Cystectomy Among Luminal Tumors.

Lotan Y, Boorjian SA, Zhang J, Bivalacqua TJ, Porten SP, Wheeler T, Lerner SP, Hutchinson R, Francis F, Davicioni E, Svatek RS, Chen CL, Black PC, Gibb EA.

Eur Urol. 2019 Aug;76(2):200-206. doi: 10.1016/j.eururo.2019.04.036. Epub 2019 May 12.


Teicoplanin Reprogrammed with the N-Acyl-Glucosamine Pharmacophore at the Penultimate Residue of Aglycone Acquires Broad-Spectrum Antimicrobial Activities Effectively Killing Gram-Positive and -Negative Pathogens.

Huang CM, Lyu SY, Lin KH, Chen CL, Chen MH, Shih HW, Hsu NS, Lo IW, Wang YL, Li YS, Wu CJ, Li TL.

ACS Infect Dis. 2019 Mar 8;5(3):430-442. doi: 10.1021/acsinfecdis.8b00317. Epub 2019 Jan 11.


Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.

Hasan SS, Sun C, Kim AS, Watanabe Y, Chen CL, Klose T, Buda G, Crispin M, Diamond MS, Klimstra WB, Rossmann MG.

Cell Rep. 2018 Dec 11;25(11):3136-3147.e5. doi: 10.1016/j.celrep.2018.11.067.


Adipokines Deregulate Cellular Communication via Epigenetic Repression of Gap Junction Loci in Obese Endometrial Cancer.

Polusani SR, Huang YW, Huang G, Chen CW, Wang CM, Lin LL, Osmulski P, Lucio ND, Liu L, Hsu YT, Zhou Y, Lin CL, Aguilera-Barrantes I, Valente PT, Kost ER, Chen CL, Shim EY, Lee SE, Ruan J, Gaczynska ME, Yan P, Goodfellow PJ, Mutch DG, Jin VX, Nicholson BJ, Huang TH, Kirma NB.

Cancer Res. 2019 Jan 1;79(1):196-208. doi: 10.1158/0008-5472.CAN-18-1615. Epub 2018 Nov 2.


A new niclosamide derivatives-B17 can inhibit urological cancers growth through apoptosis-related pathway.

Wu CL, Chen CL, Huang HS, Yu DS.

Cancer Med. 2018 Aug;7(8):3945-3954. doi: 10.1002/cam4.1635. Epub 2018 Jun 28.


Recurrent RET Gene Rearrangements in Intraductal Carcinomas of Salivary Gland.

Weinreb I, Bishop JA, Chiosea SI, Seethala RR, Perez-Ordonez B, Zhang L, Sung YS, Chen CL, Assaad A, Oliai BR, Antonescu CR.

Am J Surg Pathol. 2018 Apr;42(4):442-452. doi: 10.1097/PAS.0000000000000952.


Single-Cell RNA-seq Reveals a Subpopulation of Prostate Cancer Cells with Enhanced Cell-Cycle-Related Transcription and Attenuated Androgen Response.

Horning AM, Wang Y, Lin CK, Louie AD, Jadhav RR, Hung CN, Wang CM, Lin CL, Kirma NB, Liss MA, Kumar AP, Sun L, Liu Z, Chao WT, Wang Q, Jin VX, Chen CL, Huang TH.

Cancer Res. 2018 Feb 15;78(4):853-864. doi: 10.1158/0008-5472.CAN-17-1924. Epub 2017 Dec 12.


Mevalonate 5-diphosphate mediates ATP binding to the mevalonate diphosphate decarboxylase from the bacterial pathogen Enterococcus faecalis.

Chen CL, Mermoud JC, Paul LN, Steussy CN, Stauffacher CV.

J Biol Chem. 2017 Dec 29;292(52):21340-21351. doi: 10.1074/jbc.M117.802223. Epub 2017 Oct 12.


The Simultaneous Inhibitory Effect of Niclosamide on RANKL-Induced Osteoclast Formation and Osteoblast Differentiation.

Liu FL, Chen CL, Lee CC, Wu CC, Hsu TH, Tsai CY, Huang HS, Chang DM.

Int J Med Sci. 2017 Jul 19;14(9):840-852. doi: 10.7150/ijms.19268. eCollection 2017.


Vibrio vulnificus MARTX cytotoxin causes inactivation of phagocytosis-related signaling molecules in macrophages.

Chen CL, Chien SC, Leu TH, Harn HI, Tang MJ, Hor LI.

J Biomed Sci. 2017 Aug 19;24(1):58. doi: 10.1186/s12929-017-0368-2.


Lrp, a global regulator, regulates the virulence of Vibrio vulnificus.

Ho YC, Hung FR, Weng CH, Li WT, Chuang TH, Liu TL, Lin CY, Lo CJ, Chen CL, Chen JW, Hashimoto M, Hor LI.

J Biomed Sci. 2017 Aug 11;24(1):54. doi: 10.1186/s12929-017-0361-9.


Application of transoral continuous intraoperative neuromonitoring in natural orifice transluminal endoscopic surgery for thyroid disease: a preliminary study.

Chen HK, Chen CL, Wen KS, Lin YF, Lin KY, Uen YH.

Surg Endosc. 2018 Jan;32(1):517-525. doi: 10.1007/s00464-017-5656-0. Epub 2017 Jun 22.


TFG-MET fusion in an infantile spindle cell sarcoma with neural features.

Flucke U, van Noesel MM, Wijnen M, Zhang L, Chen CL, Sung YS, Antonescu CR.

Genes Chromosomes Cancer. 2017 Sep;56(9):663-667. doi: 10.1002/gcc.22470. Epub 2017 Jun 27.


Integrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence.

Sunkel B, Wu D, Chen Z, Wang CM, Liu X, Ye Z, Horning AM, Liu J, Mahalingam D, Lopez-Nicora H, Lin CL, Goodfellow PJ, Clinton SK, Jin VX, Chen CL, Huang TH, Wang Q.

Nucleic Acids Res. 2017 Jun 20;45(11):6993. doi: 10.1093/nar/gkx282. No abstract available.

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