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Items: 1 to 20 of 163


Transcriptionally elevation of miR-494 by new ChlA-F compound via a HuR/JunB axis inhibits human bladder cancer cell invasion.

Tian Z, Luo Y, Zhu J, Hua X, Xu J, Huang C, Jin H, Huang H, Huang C.

Biochim Biophys Acta Gene Regul Mech. 2019 Jun 2. pii: S1874-9399(19)30018-5. doi: 10.1016/j.bbagrm.2019.05.007. [Epub ahead of print]


MicroRNA-3648 Is Upregulated to Suppress TCF21, Resulting in Promotion of Invasion and Metastasis of Human Bladder Cancer.

Sun W, Li S, Yu Y, Jin H, Xie Q, Hua X, Wang S, Tian Z, Zhang H, Jiang G, Huang C, Huang H.

Mol Ther Nucleic Acids. 2019 Jun 7;16:519-530. doi: 10.1016/j.omtn.2019.04.006. Epub 2019 Apr 14.


ATG7 Promotes Bladder Cancer Invasion via Autophagy-Mediated Increased ARHGDIB mRNA Stability.

Zhu J, Tian Z, Li Y, Hua X, Zhang D, Li J, Jin H, Xu J, Chen W, Niu B, Wu XR, Comincini S, Huang H, Huang C.

Adv Sci (Weinh). 2019 Feb 22;6(8):1801927. doi: 10.1002/advs.201801927. eCollection 2019 Apr 17.


miR-3687 Overexpression Promotes Bladder Cancer Cell Growth by Inhibiting the Negative Effect of FOXP1 on Cyclin E2 Transcription.

Xie Q, Chen C, Li H, Xu J, Wu L, Yu Y, Ren S, Li H, Hua X, Yan H, Rao D, Zhang H, Jin H, Huang H, Huang C.

Mol Ther. 2019 May 8;27(5):1028-1038. doi: 10.1016/j.ymthe.2019.03.006. Epub 2019 Mar 15.


A Feedback Loop Formed by ATG7/Autophagy, FOXO3a/miR-145 and PD-L1 Regulates Stem-Like Properties and Invasion in Human Bladder Cancer.

Zhu J, Li Y, Luo Y, Xu J, Liufu H, Tian Z, Huang C, Li J, Huang C.

Cancers (Basel). 2019 Mar 12;11(3). pii: E349. doi: 10.3390/cancers11030349.


MEG3, as a Competing Endogenous RNA, Binds with miR-27a to Promote PHLPP2 Protein Translation and Impairs Bladder Cancer Invasion.

Huang C, Liao X, Jin H, Xie F, Zheng F, Li J, Zhou C, Jiang G, Wu XR, Huang C.

Mol Ther Nucleic Acids. 2019 Jun 7;16:51-62. doi: 10.1016/j.omtn.2019.01.014. Epub 2019 Feb 7.


Autophagy-mediated Mir6981 degradation exhibits CDKN1B promotion of PHLPP1 protein translation.

Peng M, Wang J, Tian Z, Zhang D, Jin H, Liu C, Xu J, Li J, Hua X, Xu J, Huang C, Huang C.

Autophagy. 2019 Mar 1:1-16. doi: 10.1080/15548627.2019.1586254. [Epub ahead of print]


The RING domain in the anti-apoptotic protein XIAP stabilizes c-Myc protein and preserves anchorage-independent growth of bladder cancer cells.

Jiang G, Huang C, Liao X, Li J, Wu XR, Zeng F, Huang C.

J Biol Chem. 2019 Apr 12;294(15):5935-5944. doi: 10.1074/jbc.RA118.005621. Epub 2019 Feb 28.


CD44s is a crucial ATG7 downstream regulator for stem-like property, invasion, and lung metastasis of human bladder cancer (BC) cells.

Zhu J, Huang G, Hua X, Li Y, Yan H, Che X, Tian Z, Liufu H, Huang C, Li J, Xu J, Dai W, Huang H, Huang C.

Oncogene. 2019 Apr;38(17):3301-3315. doi: 10.1038/s41388-018-0664-7. Epub 2019 Jan 11.


ISO, via Upregulating MiR-137 Transcription, Inhibits GSK3β-HSP70-MMP-2 Axis, Resulting in Attenuating Urothelial Cancer Invasion.

Guo X, Huang H, Jin H, Xu J, Risal S, Li J, Li X, Yan H, Zeng X, Xue L, Chen C, Huang C.

Mol Ther Nucleic Acids. 2018 Sep 7;12:337-349. doi: 10.1016/j.omtn.2018.05.017. Epub 2018 Jul 4.


New compound ChlA-F induces autophagy-dependent anti-cancer effect via upregulating Sestrin-2 in human bladder cancer.

Hua X, Xu J, Deng X, Xu J, Li J, Zhu DQ, Zhu J, Jin H, Tian Z, Huang H, Zhao QS, Huang C.

Cancer Lett. 2018 Nov 1;436:38-51. doi: 10.1016/j.canlet.2018.08.013. Epub 2018 Aug 16.


Decreased c-Myc mRNA Stability via the MicroRNA 141-3p/AUF1 Axis Is Crucial for p63α Inhibition of Cyclin D1 Gene Transcription and Bladder Cancer Cell Tumorigenicity.

Li X, Tian Z, Jin H, Xu J, Hua X, Yan H, Liufu H, Wang J, Li J, Zhu J, Huang H, Huang C.

Mol Cell Biol. 2018 Oct 15;38(21). pii: e00273-18. doi: 10.1128/MCB.00273-18. Print 2018 Nov 1.


PHLPP2 stabilization by p27 mediates its inhibition of bladder cancer invasion by promoting autophagic degradation of MMP2 protein.

Peng M, Wang J, Zhang D, Jin H, Li J, Wu XR, Huang C.

Oncogene. 2018 Jun 21. doi: 10.1038/s41388-018-0374-1. [Epub ahead of print]


MicroRNA-411 Downregulation Enhances Tumor Growth by Upregulating MLLT11 Expression in Human Bladder Cancer.

Jin H, Sun W, Zhang Y, Yan H, Liufu H, Wang S, Chen C, Gu J, Hua X, Zhou L, Jiang G, Rao D, Xie Q, Huang H, Huang C.

Mol Ther Nucleic Acids. 2018 Jun 1;11:312-322. doi: 10.1016/j.omtn.2018.03.003. Epub 2018 Mar 10.


Transcriptional and post-transcriptional upregulation of p27 mediates growth inhibition of isorhapontigenin (ISO) on human bladder cancer cells.

Jiang G, Huang C, Li J, Huang H, Wang J, Li Y, Xie F, Jin H, Zhu J, Huang C.

Carcinogenesis. 2018 Mar 8;39(3):482-492. doi: 10.1093/carcin/bgy015.


XIAP overexpression promotes bladder cancer invasion in vitro and lung metastasis in vivo via enhancing nucleolin-mediated Rho-GDIβ mRNA stability.

Yu Y, Jin H, Xu J, Gu J, Li X, Xie Q, Huang H, Li J, Tian Z, Jiang G, Chen C, He F, Wu XR, Huang C.

Int J Cancer. 2018 May 15;142(10):2040-2055. doi: 10.1002/ijc.31223. Epub 2017 Dec 28.


Mitochondrial catalase induces cells transformation through nucleolin-dependent Cox-2 mRNA stabilization.

Liao X, Huang C, Zhang D, Wang J, Li J, Jin H, Huang C.

Free Radic Biol Med. 2017 Dec;113:478-486. doi: 10.1016/j.freeradbiomed.2017.10.387. Epub 2017 Oct 31.


RhoGDIβ promotes Sp1/MMP-2 expression and bladder cancer invasion through perturbing miR-200c-targeted JNK2 protein translation.

Huang H, Jin H, Zhao H, Wang J, Li X, Yan H, Wang S, Guo X, Xue L, Li J, Peng M, Wang A, Zhu J, Wu XR, Chen C, Huang C.

Mol Oncol. 2017 Nov;11(11):1579-1594. doi: 10.1002/1878-0261.12132. Epub 2017 Sep 11.


p63α protein up-regulates heat shock protein 70 expression via E2F1 transcription factor 1, promoting Wasf3/Wave3/MMP9 signaling and bladder cancer invasion.

Jin H, Xie Q, Guo X, Xu J, Wang A, Li J, Zhu J, Wu XR, Huang H, Huang C.

J Biol Chem. 2017 Sep 22;292(38):15952-15963. doi: 10.1074/jbc.M117.792010. Epub 2017 Aug 9.

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