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Items: 1 to 20 of 76


Effects of tendon injury on uninjured regional tendons in the distal limb: An in-vivo study using an ovine tendinopathy model.

Tsang AS, Dart AJ, Biasutti SA, Jeffcott LB, Smith MM, Little CB.

PLoS One. 2019 Apr 23;14(4):e0215830. doi: 10.1371/journal.pone.0215830. eCollection 2019.


Stem Cell-Derived Extracellular Vesicles for Treating Joint Injury and Osteoarthritis.

Li JJ, Hosseini-Beheshti E, Grau GE, Zreiqat H, Little CB.

Nanomaterials (Basel). 2019 Feb 14;9(2). pii: E261. doi: 10.3390/nano9020261. Review.


Developing strategic priorities in osteoarthritis research: Proceedings and recommendations arising from the 2017 Australian Osteoarthritis Summit.

Hunter DJ, Nicolson PJA, Little CB, Robbins SR, Wang X, Bennell KL.

BMC Musculoskelet Disord. 2019 Feb 13;20(1):74. doi: 10.1186/s12891-019-2455-x.


Elevated hypertrophy, growth plate maturation, glycosaminoglycan deposition, and exostosis formation in the Hspg2 exon 3 null mouse intervertebral disc.

Shu CC, Smith SM, Little CB, Melrose J.

Biochem J. 2019 Jan 18;476(2):225-243. doi: 10.1042/BCJ20180695.


Identification of TGFβ-related genes regulated in murine osteoarthritis and chondrocyte hypertrophy by comparison of multiple microarray datasets.

de Kroon LMG, van den Akker GGH, Brachvogel B, Narcisi R, Belluoccio D, Jenner F, Bateman JF, Little CB, Brama PAJ, Blaney Davidson EN, van der Kraan PM, van Osch GJVM.

Bone. 2018 Nov;116:67-77. doi: 10.1016/j.bone.2018.07.008. Epub 2018 Jul 21.


Macrophage polarization contributes to local inflammation and structural change in the multifidus muscle after intervertebral disc injury.

James G, Sluka KA, Blomster L, Hall L, Schmid AB, Shu CC, Little CB, Melrose J, Hodges PW.

Eur Spine J. 2018 Aug;27(8):1744-1756. doi: 10.1007/s00586-018-5652-7. Epub 2018 Jun 12.


The role of fat and inflammation in the pathogenesis and management of osteoarthritis.

Urban H, Little CB.

Rheumatology (Oxford). 2018 May 1;57(suppl_4):iv10-iv21. doi: 10.1093/rheumatology/kex399. Review.


Comprehensive Expression Analysis of microRNAs and mRNAs in Synovial Tissue from a Mouse Model of Early Post-Traumatic Osteoarthritis.

Kung LHW, Ravi V, Rowley L, Bell KM, Little CB, Bateman JF.

Sci Rep. 2017 Dec 18;7(1):17701. doi: 10.1038/s41598-017-17545-1.


Cell Clusters Are Indicative of Stem Cell Activity in the Degenerate Intervertebral Disc: Can Their Properties Be Manipulated to Improve Intrinsic Repair of the Disc?

Brown S, Matta A, Erwin M, Roberts S, Gruber HE, Hanley EN Jr, Little CB, Melrose J.

Stem Cells Dev. 2018 Feb 1;27(3):147-165. doi: 10.1089/scd.2017.0213. Epub 2018 Jan 16. Review.


Cartilage MicroRNA Dysregulation During the Onset and Progression of Mouse Osteoarthritis Is Independent of Aggrecanolysis and Overlaps With Candidates From End-Stage Human Disease.

Kung LHW, Ravi V, Rowley L, Angelucci C, Fosang AJ, Bell KM, Little CB, Bateman JF.

Arthritis Rheumatol. 2018 Mar;70(3):383-395. doi: 10.1002/art.40378. Epub 2018 Feb 6.


Biomarkers for equine joint injury and osteoarthritis.

McIlwraith CW, Kawcak CE, Frisbie DD, Little CB, Clegg PD, Peffers MJ, Karsdal MA, Ekman S, Laverty S, Slayden RA, Sandell LJ, Lohmander LS, Kraus VB.

J Orthop Res. 2018 Mar;36(3):823-831. doi: 10.1002/jor.23738. Epub 2018 Jan 24.


Bioengineered Temporomandibular Joint Disk Implants: Study Protocol for a Two-Phase Exploratory Randomized Preclinical Pilot Trial in 18 Black Merino Sheep (TEMPOJIMS).

Ângelo DF, Monje FG, González-García R, Little CB, Mónico L, Pinho M, Santos FA, Carrapiço B, Gonçalves SC, Morouço P, Alves N, Moura C, Wang Y, Jeffries E, Gao J, Sousa R, Neto LL, Caldeira D, Salvado F.

JMIR Res Protoc. 2017 Mar 2;6(3):e37. doi: 10.2196/resprot.6779.


The biology of meniscal pathology in osteoarthritis and its contribution to joint disease: beyond simple mechanics.

Melrose J, Fuller ES, Little CB.

Connect Tissue Res. 2017 May - Jul;58(3-4):282-294. doi: 10.1080/03008207.2017.1284824. Epub 2017 Jan 25. Review.


Use of FGF-2 and FGF-18 to direct bone marrow stromal stem cells to chondrogenic and osteogenic lineages.

Shu C, Smith SM, Little CB, Melrose J.

Future Sci OA. 2016 Sep 22;2(4):FSO142. doi: 10.4155/fsoa-2016-0034. eCollection 2016 Dec.


Hyaluronan oligosaccharides stimulate matrix metalloproteinase and anabolic gene expression in vitro by intervertebral disc cells and annular repair in vivo.

Fuller ES, Shu C, Smith MM, Little CB, Melrose J.

J Tissue Eng Regen Med. 2018 Jan;12(1):e216-e226. doi: 10.1002/term.2319. Epub 2017 Mar 22.


Interleukin-1α induces focal degradation of biglycan and tissue degeneration in an in-vitro ovine meniscal model.

Fuller E, Little CB, Melrose J.

Exp Mol Pathol. 2016 Oct;101(2):214-220. doi: 10.1016/j.yexmp.2016.09.001. Epub 2016 Sep 9.


Joint loads resulting in ACL rupture: Effects of age, sex, and body mass on injury load and mode of failure in a mouse model.

Blaker CL, Little CB, Clarke EC.

J Orthop Res. 2017 Aug;35(8):1754-1763. doi: 10.1002/jor.23418. Epub 2016 Sep 19.

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