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Items: 1 to 20 of 107


Media photo-degradation in pharmaceutical biotechnology - impact of ambient light on media quality, cell physiology, and IgG production in CHO cultures.

Neutsch L, Kroll P, Brunner M, Pansy A, Kovar M, Herwig C, Klein T.

J Chem Technol Biotechnol. 2018 Aug;93(8):2141-2151. doi: 10.1002/jctb.5643. Epub 2018 Jun 1.


Characterizing the effect of expression of an acetyl-CoA synthetase insensitive to acetylation on co-utilization of glucose and acetate in batch and continuous cultures of E. coli W.

Novak K, Flöckner L, Erian AM, Freitag P, Herwig C, Pflügl S.

Microb Cell Fact. 2018 Jul 9;17(1):109. doi: 10.1186/s12934-018-0955-2.


Increased poly-β-hydroxybutyrate production from carbon dioxide in randomly mutated cells of cyanobacterial strain Synechocystis sp. PCC 6714: Mutant generation and characterization.

Kamravamanesh D, Kovacs T, Pflügl S, Druzhinina I, Kroll P, Lackner M, Herwig C.

Bioresour Technol. 2018 Oct;266:34-44. doi: 10.1016/j.biortech.2018.06.057. Epub 2018 Jun 20.


Multivariate analytics of chromatographic data: Visual computing based on moving window factor models.

Steinwandter V, Šišmiš M, Sagmeister P, Bodenhofer U, Herwig C.

J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Aug 15;1092:179-190. doi: 10.1016/j.jchromb.2018.06.010. Epub 2018 Jun 5.


Lecithin is the key material attribute in soy bean oil affecting filamentous bioprocesses.

Hofer A, Herwig C, Spadiut O.

AMB Express. 2018 Jun 1;8(1):90. doi: 10.1186/s13568-018-0625-0.


Optimization of sample preparation for intact cell mass spectrometry (matrix-assisted laser desorption/ionization linear time-of-flight mass spectrometry) of endophytic Xylaria.

da Silva Amaral L, Rodrigues-Filho E, Kubicek CP, Herwig C, Marchetti-Deschmann M, Allmaier G.

Rapid Commun Mass Spectrom. 2018 May 30;32(10):815-823. doi: 10.1002/rcm.8098.


The filamentous fungal pellet-relationship between morphology and productivity.

Veiter L, Rajamanickam V, Herwig C.

Appl Microbiol Biotechnol. 2018 Apr;102(7):2997-3006. doi: 10.1007/s00253-018-8818-7. Epub 2018 Feb 22. Review.


Impact of Glycerol as Carbon Source onto Specific Sugar and Inducer Uptake Rates and Inclusion Body Productivity in E. coli BL21(DE3).

Kopp J, Slouka C, Ulonska S, Kager J, Fricke J, Spadiut O, Herwig C.

Bioengineering (Basel). 2017 Dec 21;5(1). pii: E1. doi: 10.3390/bioengineering5010001.


Prediction of filamentous process performance attributes by CSL quality assessment using mid-infrared spectroscopy and chemometrics.

Hofer A, Kamravamanesh D, Bona-Lovasz J, Limbeck A, Lendl B, Herwig C, Fricke J.

J Biotechnol. 2018 Jan 10;265:93-100. doi: 10.1016/j.jbiotec.2017.11.010. Epub 2017 Nov 23.


Model-Based Methods in the Biopharmaceutical Process Lifecycle.

Kroll P, Hofer A, Ulonska S, Kager J, Herwig C.

Pharm Res. 2017 Dec;34(12):2596-2613. doi: 10.1007/s11095-017-2308-y. Epub 2017 Nov 22.


Teaching an old pET new tricks: tuning of inclusion body formation and properties by a mixed feed system in E. coli.

Wurm DJ, Quehenberger J, Mildner J, Eggenreich B, Slouka C, Schwaighofer A, Wieland K, Lendl B, Rajamanickam V, Herwig C, Spadiut O.

Appl Microbiol Biotechnol. 2018 Jan;102(2):667-676. doi: 10.1007/s00253-017-8641-6. Epub 2017 Nov 20.


Workflow for Target-Oriented Parametrization of an Enhanced Mechanistic Cell Culture Model.

Ulonska S, Kroll P, Fricke J, Clemens C, Voges R, Müller MM, Herwig C.

Biotechnol J. 2018 Apr;13(4):e1700395. doi: 10.1002/biot.201700395. Epub 2017 Dec 8.


Integrated Process Modeling-A Process Validation Life Cycle Companion.

Zahel T, Hauer S, Mueller EM, Murphy P, Abad S, Vasilieva E, Maurer D, Brocard C, Reinisch D, Sagmeister P, Herwig C.

Bioengineering (Basel). 2017 Oct 17;4(4). pii: E86. doi: 10.3390/bioengineering4040086.


Workflow for Criticality Assessment Applied in Biopharmaceutical Process Validation Stage 1.

Zahel T, Marschall L, Abad S, Vasilieva E, Maurer D, Mueller EM, Murphy P, Natschläger T, Brocard C, Reinisch D, Sagmeister P, Herwig C.

Bioengineering (Basel). 2017 Oct 12;4(4). pii: E85. doi: 10.3390/bioengineering4040085.


Morphological analysis of the filamentous fungus Penicillium chrysogenum using flow cytometry-the fast alternative to microscopic image analysis.

Ehgartner D, Herwig C, Fricke J.

Appl Microbiol Biotechnol. 2017 Oct;101(20):7675-7688. doi: 10.1007/s00253-017-8475-2. Epub 2017 Sep 14.


Soft sensor for monitoring biomass subpopulations in mammalian cell culture processes.

Kroll P, Stelzer IV, Herwig C.

Biotechnol Lett. 2017 Nov;39(11):1667-1673. doi: 10.1007/s10529-017-2408-0. Epub 2017 Aug 7.


An automated data-driven DSP development approach for glycoproteins from yeast.

Rajamanickam V, Krippl M, Herwig C, Spadiut O.

Electrophoresis. 2017 Nov;38(22-23):2886-2891. doi: 10.1002/elps.201700229. Epub 2017 Sep 20.


Toward a Noninvasive, Label-Free Screening Method for Determining Spore Inoculum Quality of Penicillium chrysogenum Using Raman Spectroscopy.

Wieland K, Kuligowski J, Ehgartner D, Ramer G, Koch C, Ofner J, Herwig C, Lendl B.

Appl Spectrosc. 2017 Dec;71(12):2661-2669. doi: 10.1177/0003702817727728. Epub 2017 Sep 15.


A combination of HPLC and automated data analysis for monitoring the efficiency of high-pressure homogenization.

Eggenreich B, Rajamanickam V, Wurm DJ, Fricke J, Herwig C, Spadiut O.

Microb Cell Fact. 2017 Aug 1;16(1):134. doi: 10.1186/s12934-017-0749-y.


Automatic feed phase identification in multivariate bioprocess profiles by sequential binary classification.

Nikzad-Langerodi R, Lughofer E, Saminger-Platz S, Zahel T, Sagmeister P, Herwig C.

Anal Chim Acta. 2017 Aug 22;982:48-61. doi: 10.1016/j.aca.2017.05.034. Epub 2017 Jun 22.


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