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Items: 1 to 20 of 45


Chemical probing for examining the structure of modified RNAs and ligand binding to RNA.

Waduge P, Sakakibara Y, Chow CS.

Methods. 2018 Nov 2. pii: S1046-2023(18)30200-7. doi: 10.1016/j.ymeth.2018.10.015. [Epub ahead of print]


Exposure to multiple career pathways by biomedical doctoral students at a public research university.

Mathur A, Chow CS, Feig AL, Kenaga H, Moldenhauer JA, Muthunayake NS, Ouellett ML, Pence LE, Straub V.

PLoS One. 2018 Jun 22;13(6):e0199720. doi: 10.1371/journal.pone.0199720. eCollection 2018.


Redox-Inactive Peptide Disrupting Trx1-Ask1 Interaction for Selective Activation of Stress Signaling.

Kekulandara DN, Nagi S, Seo H, Chow CS, Ahn YH.

Biochemistry. 2018 Feb 6;57(5):772-780. doi: 10.1021/acs.biochem.7b01083. Epub 2018 Jan 5.


Pseudouridine modifications influence binding of aminoglycosides to helix 69 of bacterial ribosomes.

Sakakibara Y, Chow CS.

Org Biomol Chem. 2017 Oct 18;15(40):8535-8543. doi: 10.1039/c7ob02147j.


The development of peptide ligands that target helix 69 rRNA of bacterial ribosomes.

Dremann DN, Chow CS.

Bioorg Med Chem. 2016 Sep 15;24(18):4486-4491. doi: 10.1016/j.bmc.2016.07.050. Epub 2016 Jul 25.


Post-transcriptional Modifications Modulate rRNA Structure and Ligand Interactions.

Jiang J, Seo H, Chow CS.

Acc Chem Res. 2016 May 17;49(5):893-901. doi: 10.1021/acs.accounts.6b00014. Epub 2016 Apr 11.


Cisplatin Targeting of Bacterial Ribosomal RNA Hairpins.

Dedduwa-Mudalige GN, Chow CS.

Int J Mol Sci. 2015 Sep 7;16(9):21392-409. doi: 10.3390/ijms160921392.


Modulation of conformational changes in helix 69 mutants by pseudouridine modifications.

Jiang J, Kharel DN, Chow CS.

Biophys Chem. 2015 May-Jun;200-201:48-55. doi: 10.1016/j.bpc.2015.03.001. Epub 2015 Mar 11.


Amino acid-linked platinum(II) analogues have altered specificity for RNA compared to cisplatin.

Rijal K, Bao X, Chow CS.

Chem Commun (Camb). 2014 Apr 18;50(30):3918-20. doi: 10.1039/c3cc49035a. Epub 2014 Jan 13.


Structure modulation of helix 69 from Escherichia coli 23S ribosomal RNA by pseudouridylations.

Jiang J, Aduri R, Chow CS, SantaLucia J Jr.

Nucleic Acids Res. 2014 Apr;42(6):3971-81. doi: 10.1093/nar/gkt1329. Epub 2013 Dec 26.


Probing the stabilizing effects of modified nucleotides in the bacterial decoding region of 16S ribosomal RNA.

Mahto SK, Chow CS.

Bioorg Med Chem. 2013 May 15;21(10):2720-6. doi: 10.1016/j.bmc.2013.03.010. Epub 2013 Mar 21.


Selection of heptapeptides that bind helix 69 of bacterial 23S ribosomal RNA.

Kaur M, Rupasinghe CN, Klosi E, Spaller MR, Chow CS.

Bioorg Med Chem. 2013 Mar 1;21(5):1240-7. doi: 10.1016/j.bmc.2012.12.048. Epub 2013 Jan 10.


Ligand- and pH-induced conformational changes of RNA domain helix 69 revealed by 2-aminopurine fluorescence.

Sakakibara Y, Abeysirigunawardena SC, Duc AC, Dremann DN, Chow CS.

Angew Chem Int Ed Engl. 2012 Nov 26;51(48):12095-8. doi: 10.1002/anie.201206000. Epub 2012 Oct 24. No abstract available.


Role of pseudouridine in structural rearrangements of helix 69 during bacterial ribosome assembly.

Sakakibara Y, Chow CS.

ACS Chem Biol. 2012 May 18;7(5):871-8. doi: 10.1021/cb200497q. Epub 2012 Feb 24.


Comparison of solution conformations and stabilities of modified helix 69 rRNA analogs from bacteria and human.

Sumita M, Jiang J, SantaLucia J Jr, Chow CS.

Biopolymers. 2012 Feb;97(2):94-106. doi: 10.1002/bip.21706. Epub 2011 Aug 19.


Single-molecule FRET reveals a cooperative effect of two methyl group modifications in the folding of human mitochondrial tRNA(Lys).

Kobitski AY, Hengesbach M, Seidu-Larry S, Dammertz K, Chow CS, van Aerschot A, Nienhaus GU, Helm M.

Chem Biol. 2011 Jul 29;18(7):928-36. doi: 10.1016/j.chembiol.2011.03.016.


Probing conformational states of modified helix 69 in 50S ribosomes.

Sakakibara Y, Chow CS.

J Am Chem Soc. 2011 Jun 8;133(22):8396-9. doi: 10.1021/ja2005658. Epub 2011 May 16.


Selection of peptides targeting helix 31 of bacterial 16S ribosomal RNA by screening M13 phage-display libraries.

Lamichhane TN, Abeydeera ND, Duc AC, Cunningham PR, Chow CS.

Molecules. 2011 Jan 28;16(2):1211-39. doi: 10.3390/molecules16021211.


A modified fluorescent intercalator displacement assay for RNA ligand discovery.

Asare-Okai PN, Chow CS.

Anal Biochem. 2011 Jan 15;408(2):269-76. doi: 10.1016/j.ab.2010.09.020. Epub 2010 Sep 21.


Selection of peptides that target the aminoacyl-tRNA site of bacterial 16S ribosomal RNA.

Li M, Duc AC, Klosi E, Pattabiraman S, Spaller MR, Chow CS.

Biochemistry. 2009 Sep 8;48(35):8299-311. doi: 10.1021/bi900982t.

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