Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 35

1.

Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids.

Groveman BR, Foliaki ST, Orru CD, Zanusso G, Carroll JA, Race B, Haigh CL.

Acta Neuropathol Commun. 2019 Jun 14;7(1):90. doi: 10.1186/s40478-019-0742-2. Erratum in: Acta Neuropathol Commun. 2019 Aug 14;7(1):131.

2.

Association of Blood and Cerebrospinal Fluid Tau Level and Other Biomarkers With Survival Time in Sporadic Creutzfeldt-Jakob Disease.

Staffaroni AM, Kramer AO, Casey M, Kang H, Rojas JC, Orrú CD, Caughey B, Allen IE, Kramer JH, Rosen HJ, Blennow K, Zetterberg H, Geschwind MD.

JAMA Neurol. 2019 May 6. doi: 10.1001/jamaneurol.2019.1071. [Epub ahead of print]

PMID:
31058916
3.

Early and Pre-Clinical Detection of Prion Seeding Activity in Cerebrospinal Fluid of Goats using Real-Time Quaking-Induced Conversion Assay.

Favole A, Mazza M, Vallino Costassa E, D'Angelo A, Lombardi G, Marconi P, Crociara P, Berrone E, Gallo M, Palmitessa C, Orrù CD, Caughey B, Acutis PL, Caramelli M, Casalone C, Corona C.

Sci Rep. 2019 Apr 16;9(1):6173. doi: 10.1038/s41598-019-42449-7.

4.

Publisher Correction: Early preclinical detection of prions in the skin of prion-infected animals.

Wang Z, Manca M, Foutz A, Camacho MV, Raymond GJ, Race B, Orru CD, Yuan J, Shen P, Li B, Lang Y, Dang J, Adornato A, Williams K, Maurer NR, Gambetti P, Xu B, Surewicz W, Petersen RB, Dong X, Appleby BS, Caughey B, Cui L, Kong Q, Zou WQ.

Nat Commun. 2019 Feb 4;10(1):640. doi: 10.1038/s41467-019-08648-6.

5.

Early preclinical detection of prions in the skin of prion-infected animals.

Wang Z, Manca M, Foutz A, Camacho MV, Raymond GJ, Race B, Orru CD, Yuan J, Shen P, Li B, Lang Y, Dang J, Adornato A, Williams K, Maurer NR, Gambetti P, Xu B, Surewicz W, Petersen RB, Dong X, Appleby BS, Caughey B, Cui L, Kong Q, Zou WQ.

Nat Commun. 2019 Jan 16;10(1):247. doi: 10.1038/s41467-018-08130-9. Erratum in: Nat Commun. 2019 Feb 4;10(1):640.

6.

Prion Seeds Distribute throughout the Eyes of Sporadic Creutzfeldt-Jakob Disease Patients.

Orrù CD, Soldau K, Cordano C, Llibre-Guerra J, Green AJ, Sanchez H, Groveman BR, Edland SD, Safar JG, Lin JH, Caughey B, Geschwind MD, Sigurdson CJ.

mBio. 2018 Nov 20;9(6). pii: e02095-18. doi: 10.1128/mBio.02095-18.

7.

Ultrasensitive RT-QuIC Seed Amplification Assays for Disease-Associated Tau, α-Synuclein, and Prion Aggregates.

Saijo E, Groveman BR, Kraus A, Metrick M, Orrù CD, Hughson AG, Caughey B.

Methods Mol Biol. 2019;1873:19-37. doi: 10.1007/978-1-4939-8820-4_2.

PMID:
30341601
8.

Lack of Transmission of Chronic Wasting Disease to Cynomolgus Macaques.

Race B, Williams K, Orrú CD, Hughson AG, Lubke L, Chesebro B.

J Virol. 2018 Jun 29;92(14). pii: e00550-18. doi: 10.1128/JVI.00550-18. Print 2018 Jul 15.

9.

Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC.

Groveman BR, Orrù CD, Hughson AG, Raymond LD, Zanusso G, Ghetti B, Campbell KJ, Safar J, Galasko D, Caughey B.

Acta Neuropathol Commun. 2018 Feb 9;6(1):7. doi: 10.1186/s40478-018-0508-2.

10.

Prion seeding activity and infectivity in skin samples from patients with sporadic Creutzfeldt-Jakob disease.

Orrú CD, Yuan J, Appleby BS, Li B, Li Y, Winner D, Wang Z, Zhan YA, Rodgers M, Rarick J, Wyza RE, Joshi T, Wang GX, Cohen ML, Zhang S, Groveman BR, Petersen RB, Ironside JW, Quiñones-Mateu ME, Safar JG, Kong Q, Caughey B, Zou WQ.

Sci Transl Med. 2017 Nov 22;9(417). pii: eaam7785. doi: 10.1126/scitranslmed.aam7785.

11.

Role of the central lysine cluster and scrapie templating in the transmissibility of synthetic prion protein aggregates.

Groveman BR, Raymond GJ, Campbell KJ, Race B, Raymond LD, Hughson AG, Orrú CD, Kraus A, Phillips K, Caughey B.

PLoS Pathog. 2017 Sep 14;13(9):e1006623. doi: 10.1371/journal.ppat.1006623. eCollection 2017 Sep.

12.

RT-QuIC Assays for Prion Disease Detection and Diagnostics.

Orrù CD, Groveman BR, Hughson AG, Manca M, Raymond LD, Raymond GJ, Campbell KJ, Anson KJ, Kraus A, Caughey B.

Methods Mol Biol. 2017;1658:185-203. doi: 10.1007/978-1-4939-7244-9_14.

PMID:
28861791
13.

Amplified Detection of Prions and Other Amyloids by RT-QuIC in Diagnostics and the Evaluation of Therapeutics and Disinfectants.

Caughey B, Orru CD, Groveman BR, Hughson AG, Manca M, Raymond LD, Raymond GJ, Race B, Saijo E, Kraus A.

Prog Mol Biol Transl Sci. 2017;150:375-388. doi: 10.1016/bs.pmbts.2017.06.003. Epub 2017 Jul 27. Review.

PMID:
28838670
14.

Self-propagating, protease-resistant, recombinant prion protein conformers with or without in vivo pathogenicity.

Wang F, Wang X, Orrú CD, Groveman BR, Surewicz K, Abskharon R, Imamura M, Yokoyama T, Kim YS, Vander Stel KJ, Sinniah K, Priola SA, Surewicz WK, Caughey B, Ma J.

PLoS Pathog. 2017 Jul 12;13(7):e1006491. doi: 10.1371/journal.ppat.1006491. eCollection 2017 Jul.

15.

Extended and direct evaluation of RT-QuIC assays for Creutzfeldt-Jakob disease diagnosis.

Groveman BR, Orrú CD, Hughson AG, Bongianni M, Fiorini M, Imperiale D, Ladogana A, Pocchiari M, Zanusso G, Caughey B.

Ann Clin Transl Neurol. 2016 Dec 27;4(2):139-144. doi: 10.1002/acn3.378. eCollection 2017 Feb.

16.

The real-time quaking-induced conversion assay for detection of human prion disease and study of other protein misfolding diseases.

Schmitz M, Cramm M, Llorens F, Müller-Cramm D, Collins S, Atarashi R, Satoh K, Orrù CD, Groveman BR, Zafar S, Schulz-Schaeffer WJ, Caughey B, Zerr I.

Nat Protoc. 2016 Nov;11(11):2233-2242. doi: 10.1038/nprot.2016.120. Epub 2016 Oct 13.

PMID:
27735933
17.

Factors That Improve RT-QuIC Detection of Prion Seeding Activity.

Orrú CD, Hughson AG, Groveman BR, Campbell KJ, Anson KJ, Manca M, Kraus A, Caughey B.

Viruses. 2016 May 23;8(5). pii: E140. doi: 10.3390/v8050140.

18.

Correction for Masujin et al., Detection of Atypical H-Type Bovine Spongiform Encephalopathy and Discrimination of Bovine Prion Strains by Real-Time Quaking-Induced Conversion.

Masujin K, Orrú CD, Miyazawa K, Groveman BR, Raymond LD, Hughson AG, Caughey B.

J Clin Microbiol. 2016 May;54(5):1407. doi: 10.1128/JCM.00472-16. No abstract available.

19.

Detection of Atypical H-Type Bovine Spongiform Encephalopathy and Discrimination of Bovine Prion Strains by Real-Time Quaking-Induced Conversion.

Masujin K, Orrú CD, Miyazawa K, Groveman BR, Raymond LD, Hughson AG, Caughey B.

J Clin Microbiol. 2016 Mar;54(3):676-86. doi: 10.1128/JCM.02731-15. Epub 2016 Jan 6. Erratum in: J Clin Microbiol. 2016 May;54(5):1407.

20.

Sensitive and specific detection of classical scrapie prions in the brains of goats by real-time quaking-induced conversion.

Dassanayake RP, Orrú CD, Hughson AG, Caughey B, Graça T, Zhuang D, Madsen-Bouterse SA, Knowles DP, Schneider DA.

J Gen Virol. 2016 Mar;97(3):803-812. doi: 10.1099/jgv.0.000367. Epub 2015 Dec 10.

Supplemental Content

Loading ...
Support Center