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Items: 9


CD28 Superagonistic Activation of T Cells Induces a Tumor Cell-Like Metabolic Program.

Thaventhiran T, Wong W, Alghanem AF, Alhumeed N, Aljasir MA, Ramsey S, Sethu S, Yeang HXA, Chadwick AE, Cross M, Webb SD, Djouhri L, Ball C, Stebbings R, Sathish JG.

Monoclon Antib Immunodiagn Immunother. 2019 Apr;38(2):60-69. doi: 10.1089/mab.2018.0042.


An ELISA method to estimate the mono ADP-ribosyltransferase activities: e.g in pertussis toxin and vaccines.

Asokanathan C, Tierney S, Ball CR, Buckle G, Day A, Tanley S, Bristow A, Markey K, Xing D, Yuen CT.

Anal Biochem. 2018 Jan 1;540-541:15-19. doi: 10.1016/j.ab.2017.10.025. Epub 2017 Nov 9.


An autologous endothelial cell:peripheral blood mononuclear cell assay that detects cytokine storm responses to biologics.

Reed DM, Paschalaki KE, Starke RD, Mohamed NA, Sharp G, Fox B, Eastwood D, Bristow A, Ball C, Vessillier S, Hansel TT, Thorpe SJ, Randi AM, Stebbings R, Mitchell JA.

FASEB J. 2015 Jun;29(6):2595-602. doi: 10.1096/fj.14-268144. Epub 2015 Mar 6.


Failure to upregulate cell surface PD-1 is associated with dysregulated stimulation of T cells by TGN1412-like CD28 superagonist.

Thaventhiran T, Alhumeed N, Yeang HX, Sethu S, Downey JS, Alghanem AF, Olayanju A, Smith EL, Cross MJ, Webb SD, Williams DP, Bristow A, Ball C, Stebbings R, Sathish JG.

MAbs. 2014;6(5):1290-9. doi: 10.4161/mabs.29758. Epub 2014 Oct 30.


The breadth of cross sub-type neutralisation activity of a single domain antibody to influenza hemagglutinin can be increased by antibody valency.

Hufton SE, Risley P, Ball CR, Major D, Engelhardt OG, Poole S.

PLoS One. 2014 Aug 1;9(8):e103294. doi: 10.1371/journal.pone.0103294. eCollection 2014.


Antibody C region influences TGN1412-like functional activity in vitro.

Ball C, Fox B, Hufton S, Sharp G, Poole S, Stebbings R, Eastwood D, Findlay L, Parren PW, Thorpe R, Bristow A, Thorpe SJ.

J Immunol. 2012 Dec 15;189(12):5831-40. doi: 10.4049/jimmunol.1201795. Epub 2012 Nov 12.


Comparison of novel methods for predicting the risk of pro-inflammatory clinical infusion reactions during monoclonal antibody therapy.

Findlay L, Eastwood D, Ball C, Robinson CJ, Bird C, Wadhwa M, Thorpe SJ, Thorpe R, Stebbings R, Poole S.

J Immunol Methods. 2011 Aug 31;371(1-2):134-42. doi: 10.1016/j.jim.2011.06.022. Epub 2011 Jun 30.


Endothelial cells co-stimulate peripheral blood mononuclear cell responses to monoclonal antibody TGN1412 in culture.

Findlay L, Sharp G, Fox B, Ball C, Robinson CJ, Bird C, Stebbings R, Eastwood D, Wadhwa M, Poole S, Thorpe R, Thorpe SJ.

Cytokine. 2011 Jul;55(1):141-51. doi: 10.1016/j.cyto.2011.03.019. Epub 2011 Apr 13.


Improved in vitro methods to predict the in vivo toxicity in man of therapeutic monoclonal antibodies including TGN1412.

Findlay L, Eastwood D, Stebbings R, Sharp G, Mistry Y, Ball C, Hood J, Thorpe R, Poole S.

J Immunol Methods. 2010 Jan 31;352(1-2):1-12. doi: 10.1016/j.jim.2009.10.013. Epub 2009 Nov 4.


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