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Items: 1 to 20 of 35

1.

An integrated workflow for crosslinking mass spectrometry.

Mendes ML, Fischer L, Chen ZA, Barbon M, O'Reilly FJ, Giese SH, Bohlke-Schneider M, Belsom A, Dau T, Combe CW, Graham M, Eisele MR, Baumeister W, Speck C, Rappsilber J.

Mol Syst Biol. 2019 Sep;15(9):e8994. doi: 10.15252/msb.20198994.

2.

Chromosomal Sil system contributes to silver resistance in E. coli ATCC 8739.

Blanco Massani M, Klumpp J, Widmer M, Speck C, Nisple M, Lehmann R, Schuppler M.

Biometals. 2018 Dec;31(6):1101-1114. doi: 10.1007/s10534-018-0143-1. Epub 2018 Oct 4.

PMID:
30284644
3.

Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma.

Yu Y, Schleich K, Yue B, Ji S, Lohneis P, Kemper K, Silvis MR, Qutob N, van Rooijen E, Werner-Klein M, Li L, Dhawan D, Meierjohann S, Reimann M, Elkahloun A, Treitschke S, Dörken B, Speck C, Mallette FA, Zon LI, Holmen SL, Peeper DS, Samuels Y, Schmitt CA, Lee S.

Cancer Cell. 2018 Apr 9;33(4):785. doi: 10.1016/j.ccell.2018.03.009. No abstract available.

4.

Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma.

Yu Y, Schleich K, Yue B, Ji S, Lohneis P, Kemper K, Silvis MR, Qutob N, van Rooijen E, Werner-Klein M, Li L, Dhawan D, Meierjohann S, Reimann M, Elkahloun A, Treitschke S, Dörken B, Speck C, Mallette FA, Zon LI, Holmen SL, Peeper DS, Samuels Y, Schmitt CA, Lee S.

Cancer Cell. 2018 Feb 12;33(2):322-336.e8. doi: 10.1016/j.ccell.2018.01.002. Erratum in: Cancer Cell. 2018 Apr 9;33(4):785.

5.

Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model.

Noguchi Y, Yuan Z, Bai L, Schneider S, Zhao G, Stillman B, Speck C, Li H.

Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9529-E9538. doi: 10.1073/pnas.1712537114. Epub 2017 Oct 25.

6.

From structure to mechanism-understanding initiation of DNA replication.

Riera A, Barbon M, Noguchi Y, Reuter LM, Schneider S, Speck C.

Genes Dev. 2017 Jun 1;31(11):1073-1088. doi: 10.1101/gad.298232.117. Review.

7.

Metabolic Effects of Glucose-Fructose Co-Ingestion Compared to Glucose Alone during Exercise in Type 1 Diabetes.

Bally L, Kempf P, Zueger T, Speck C, Pasi N, Ciller C, Feller K, Loher H, Rosset R, Wilhelm M, Boesch C, Buehler T, Dokumaci AS, Tappy L, Stettler C.

Nutrients. 2017 Feb 21;9(2). pii: E164. doi: 10.3390/nu9020164.

8.

Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1.

Yuan Z, Riera A, Bai L, Sun J, Nandi S, Spanos C, Chen ZA, Barbon M, Rappsilber J, Stillman B, Speck C, Li H.

Nat Struct Mol Biol. 2017 Mar;24(3):316-324. doi: 10.1038/nsmb.3372. Epub 2017 Feb 13.

9.

Replicating repetitive DNA.

Tognetti S, Speck C.

Nat Cell Biol. 2016 May 27;18(6):593-4. doi: 10.1038/ncb3367.

10.

Exceeding the limits - Cdc45 overexpression turns bad.

Speck C.

Cell Cycle. 2016 Jul 17;15(14):1809-10. doi: 10.1080/15384101.2016.1184512. Epub 2016 May 6. No abstract available.

11.

Metabolic and hormonal response to intermittent high-intensity and continuous moderate intensity exercise in individuals with type 1 diabetes: a randomised crossover study.

Bally L, Zueger T, Buehler T, Dokumaci AS, Speck C, Pasi N, Ciller C, Paganini D, Feller K, Loher H, Rosset R, Wilhelm M, Tappy L, Boesch C, Stettler C.

Diabetologia. 2016 Apr;59(4):776-84. doi: 10.1007/s00125-015-3854-7. Epub 2016 Jan 6.

PMID:
26739816
12.

A reconstituted system reveals how activating and inhibitory interactions control DDK dependent assembly of the eukaryotic replicative helicase.

Herrera MC, Tognetti S, Riera A, Zech J, Clarke P, Fernández-Cid A, Speck C.

Nucleic Acids Res. 2015 Dec 2;43(21):10238-50. doi: 10.1093/nar/gkv881. Epub 2015 Sep 3.

13.

Cdc6 ATPase activity disengages Cdc6 from the pre-replicative complex to promote DNA replication.

Chang F, Riera A, Evrin C, Sun J, Li H, Speck C, Weinreich M.

Elife. 2015 Aug 25;4. doi: 10.7554/eLife.05795.

14.

Opening the gate to DNA replication.

Riera A, Speck C.

Cell Cycle. 2015;14(1):6-8. doi: 10.4161/15384101.2014.987624. No abstract available.

15.

The fidelity of synaptonemal complex assembly is regulated by a signaling mechanism that controls early meiotic progression.

Silva N, Ferrandiz N, Barroso C, Tognetti S, Lightfoot J, Telecan O, Encheva V, Faull P, Hanni S, Furger A, Snijders AP, Speck C, Martinez-Perez E.

Dev Cell. 2014 Nov 24;31(4):503-11. doi: 10.1016/j.devcel.2014.10.001. Epub 2014 Nov 6.

16.

Structural and mechanistic insights into Mcm2-7 double-hexamer assembly and function.

Sun J, Fernandez-Cid A, Riera A, Tognetti S, Yuan Z, Stillman B, Speck C, Li H.

Genes Dev. 2014 Oct 15;28(20):2291-303. doi: 10.1101/gad.242313.114.

17.

Switch on the engine: how the eukaryotic replicative helicase MCM2-7 becomes activated.

Tognetti S, Riera A, Speck C.

Chromosoma. 2015 Mar;124(1):13-26. doi: 10.1007/s00412-014-0489-2. Epub 2014 Oct 12. Review.

18.

A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2-7 onto DNA.

Samel SA, Fernández-Cid A, Sun J, Riera A, Tognetti S, Herrera MC, Li H, Speck C.

Genes Dev. 2014 Aug 1;28(15):1653-66. doi: 10.1101/gad.242404.114.

19.

Helicase loading: how to build a MCM2-7 double-hexamer.

Riera A, Tognetti S, Speck C.

Semin Cell Dev Biol. 2014 Jun;30:104-9. doi: 10.1016/j.semcdb.2014.03.008. Epub 2014 Mar 14. Review.

PMID:
24637008
20.

The ORC/Cdc6/MCM2-7 complex facilitates MCM2-7 dimerization during prereplicative complex formation.

Evrin C, Fernández-Cid A, Riera A, Zech J, Clarke P, Herrera MC, Tognetti S, Lurz R, Speck C.

Nucleic Acids Res. 2014 Feb;42(4):2257-69. doi: 10.1093/nar/gkt1148. Epub 2013 Nov 14.

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