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Cryptotanshinone (Dsh-003) from Salvia miltiorrhiza Bunge inhibits prostaglandin E2-induced survival and invasion effects in HA22T hepatocellular carcinoma cells.

Chang JH, Lin CH, Shibu MA, Chou YC, Liu JY, Chou YH, Shen CY, Yeh YL, Viswanadha VP, Huang CY.

Environ Toxicol. 2018 Sep 12. doi: 10.1002/tox.22633. [Epub ahead of print]


Observing Solid-State Formation of Oriented Porous Functional Oxide Nanowire Heterostructures by in Situ TEM.

Ho JH, Ting YH, Chen JY, Huang CW, Tsai TC, Lin TY, Huang CY, Wu WW.

Nano Lett. 2018 Aug 27. doi: 10.1021/acs.nanolett.8b03021. [Epub ahead of print]


Inhibition of ERK-Drp1 signaling and mitochondria fragmentation alleviates IGF-IIR-induced mitochondria dysfunction during heart failure.

Huang CY, Lai CH, Kuo CH, Chiang SF, Pai PY, Lin JY, Chang CF, Viswanadha VP, Kuo WW, Huang CY.

J Mol Cell Cardiol. 2018 Sep;122:58-68. doi: 10.1016/j.yjmcc.2018.08.006. Epub 2018 Aug 9.


Bioactive Peptide Improves Diet-Induced Hepatic Fat Deposition and Hepatocyte Proinflammatory Response in SAMP8 Ageing Mice.

Dumeus S, Shibu MA, Lin WT, Wang MF, Lai CH, Shen CY, Lin YM, Viswanadha VP, Kuo WW, Huang CY.

Cell Physiol Biochem. 2018;48(5):1942-1952. doi: 10.1159/000492518. Epub 2018 Aug 9.


Pkcδ Activation is Involved in ROS-Mediated Mitochondrial Dysfunction and Apoptosis in Cardiomyocytes Exposed to Advanced Glycation End Products (Ages).

Yang YC, Tsai CY, Chen CL, Kuo CH, Hou CW, Cheng SY, Aneja R, Huang CY, Kuo WW.

Aging Dis. 2018 Aug 1;9(4):647-663. doi: 10.14336/AD.2017.0924. eCollection 2018 Aug.


HSP40 co-chaperone protein Tid1 suppresses metastasis of head and neck cancer by inhibiting Galectin-7-TCF3-MMP9 axis signaling.

Chen YS, Chang CW, Tsay YG, Huang LY, Wu YC, Cheng LH, Yang CC, Wu CH, Teo WH, Hung KF, Huang CY, Lee TC, Lo JF.

Theranostics. 2018 Jun 13;8(14):3841-3855. doi: 10.7150/thno.25784. eCollection 2018.


The Protective Effects of Clams on Hypercholesterolemia in Late-Stage Triple-Transgenic Alzheimer's Diseased Mice Hearts.

Hsieh YL, Teng HJ, Yeh YH, Hsieh CH, Huang CY.

Mar Drugs. 2018 Aug 1;16(8). pii: E263. doi: 10.3390/md16080263.


Eriobotrya japonica ameliorates cardiac hypertrophy in H9c2 cardiomyoblast and in spontaneously hypertensive rats.

Chiang JT, Badrealam KF, Shibu MA, Kuo CH, Huang CY, Chen BC, Lin YM, Viswanadha VP, Kuo WW, Huang CY.

Environ Toxicol. 2018 Jul 4. doi: 10.1002/tox.22589. [Epub ahead of print]


Aged cells in human skeletal muscle after resistance exercise.

Yang C, Jiao Y, Wei B, Yang Z, Wu JF, Jensen J, Jean WH, Huang CY, Kuo CH.

Aging (Albany NY). 2018 Jun 27;10(6):1356-1365. doi: 10.18632/aging.101472.


ERβ targets ZAK and attenuates cellular hypertrophy via SUMO-1 modification in H9c2 cells.

Pai P, Shibu MA, Chang RL, Yang JJ, Su CC, Lai CH, Liao HE, Viswanadha VP, Kuo WW, Huang CY.

J Cell Biochem. 2018 Jun 22. doi: 10.1002/jcb.27199. [Epub ahead of print]


Anti-Apoptosis and Anti-Fibrosis Effects of Eriobotrya Japonica in Spontaneously Hypertensive Rat Hearts.

Chiang JT, Badrealam KF, Shibu MA, Cheng SF, Shen CY, Chang CF, Lin YM, Viswanadha VP, Liao SC, Huang CY.

Int J Mol Sci. 2018 May 31;19(6). pii: E1638. doi: 10.3390/ijms19061638.


A minireview of E4BP4/NFIL3 in heart failure.

Velmurugan BK, Chang RL, Marthandam Asokan S, Chang CF, Day CH, Lin YM, Lin YC, Kuo WW, Huang CY.

J Cell Physiol. 2018 Jun 1. doi: 10.1002/jcp.26790. [Epub ahead of print] Review.


17β-Estradiol and/or estrogen receptor alpha signaling blocks protein phosphatase 1 mediated ISO induced cardiac hypertrophy.

Fang HY, Hung MY, Lin YM, Pandey S, Chang CC, Lin KH, Shen CY, Viswanadha VP, Kuo WW, Huang CY.

PLoS One. 2018 May 3;13(5):e0196569. doi: 10.1371/journal.pone.0196569. eCollection 2018.


GABA tea attenuates cardiac apoptosis in spontaneously hypertensive rats (SHR) by enhancing PI3K/Akt-mediated survival pathway and suppressing Bax/Bak dependent apoptotic pathway.

Chen BC, Hung MY, Wang HF, Yeh LJ, Pandey S, Chen RJ, Chang RL, Viswanadha VP, Lin KH, Huang CY.

Environ Toxicol. 2018 Jul;33(7):789-797. doi: 10.1002/tox.22565. Epub 2018 Apr 30.


Estrogen and/or Estrogen Receptor α Inhibits BNIP3-Induced Apoptosis and Autophagy in H9c2 Cardiomyoblast Cells.

Chen BC, Weng YJ, Shibu MA, Han CK, Chen YS, Shen CY, Lin YM, Viswanadha VP, Liang HY, Huang CY.

Int J Mol Sci. 2018 Apr 26;19(5). pii: E1298. doi: 10.3390/ijms19051298.


Overexpression of ZAKβ in human osteosarcoma cells enhances ZAKα expression, resulting in a synergistic apoptotic effect.

Fu CY, Tseng YS, Chen MC, Hsu HH, Yang JJ, Tu CC, Lin YM, Viswanadha VP, Ding K, Kuo WW, Huang CY.

Cell Biochem Funct. 2018 Jun;36(4):176-182. doi: 10.1002/cbf.3329. Epub 2018 Apr 13.


Protein supplementation enhances cerebral oxygenation during exercise in elite basketball players.

Ho CF, Jiao Y, Wei B, Yang Z, Wang HY, Wu YY, Yang C, Tseng KW, Huang CY, Chen CY, Kuo CH.

Nutrition. 2018 Sep;53:34-37. doi: 10.1016/j.nut.2018.01.015. Epub 2018 Feb 5.


Platycodin D Reverses Pathological Cardiac Hypertrophy and Fibrosis in Spontaneously Hypertensive Rats.

Lin YC, Lin YC, Kuo WW, Shen CY, Cheng YC, Lin YM, Chang RL, Padma VV, Huang CY, Huang CY.

Am J Chin Med. 2018;46(3):537-549. doi: 10.1142/S0192415X18500271. Epub 2018 Mar 29.


Fisetin mediated apoptotic cell death in parental and Oxaliplatin/irinotecan resistant colorectal cancer cells in vitro and in vivo.

Jeng LB, Kumar Velmurugan B, Chen MC, Hsu HH, Ho TJ, Day CH, Lin YM, Padma VV, Tu CC, Huang CY.

J Cell Physiol. 2018 Sep;233(9):7134-7142. doi: 10.1002/jcp.26532. Epub 2018 Mar 25.


Rab9-dependent autophagy is required for the IGF-IIR triggering mitophagy to eliminate damaged mitochondria.

Huang CY, Kuo WW, Ho TJ, Chiang SF, Pai PY, Lin JY, Lin DY, Kuo CH, Huang CY.

J Cell Physiol. 2018 Sep;233(9):7080-7091. doi: 10.1002/jcp.26346. Epub 2018 Mar 25.


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